Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kshitiz Singh"'
Publikováno v:
Journal of Orthopaedic Reports, Vol 2, Iss 3, Pp 100163- (2023)
Backround: Lipoma arborescens is a very uncommon benign intra-articular tumour of unknown etiology that is characterized by diffuse villous proliferation of the synovium and replacement of the sub-synovial tissue by mature adipocytes. Patients with l
Externí odkaz:
https://doaj.org/article/2013294044bf4dbcb3b5ec68121b0483
Autor:
Sourav K. Bose, Brandon M. White, Meghana V. Kashyap, Apeksha Dave, Felix R. De Bie, Haiying Li, Kshitiz Singh, Pallavi Menon, Tiankun Wang, Shiva Teerdhala, Vishal Swaminathan, Heather A. Hartman, Sowmya Jayachandran, Prashant Chandrasekaran, Kiran Musunuru, Rajan Jain, David B. Frank, Philip Zoltick, William H. Peranteau
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Lysosomal storage diseases like mucopolysaccharidosis type I (MPS I) cause pathology before birth and result in early morbidity and mortality. Here, the authors show that in utero base editing mediates multi-organ phenotypic and survival benefits in
Externí odkaz:
https://doaj.org/article/a932a6ec2ba7497281b8dba976e50d99
Autor:
Kshitiz Singh, Denis Furling, Sumitava Dastidar, Marinee Chuah, Thierry VandenDriessche, Debanjana Majumdar, Jaitip Tipanee, Arnaud F. Klein
Publikováno v:
Molecular Therapy
Molecular Therapy, Cell Press, 2021, 29 (11), ⟨10.1016/j.ymthe.2021.08.004⟩
Molecular Therapy, 2021, 29 (11), ⟨10.1016/j.ymthe.2021.08.004⟩
Molecular Therapy, Cell Press, 2021, 29 (11), ⟨10.1016/j.ymthe.2021.08.004⟩
Molecular Therapy, 2021, 29 (11), ⟨10.1016/j.ymthe.2021.08.004⟩
CTGrepeat expansion (CTGexp) is associated with aberrant alternate splicing that contributes to cardiac dysfunction in myotonic dystrophy type 1 (DM1). Excision of thisCTGexprepeat using CRISPR-Cas resulted in the disappearance of punctate ribonuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f587adb6edc9ad1dd712e72d4e19cdfe
https://doi.org/10.1016/j.ymthe.2021.08.004
https://doi.org/10.1016/j.ymthe.2021.08.004
Publikováno v:
Genes; Volume 13; Issue 11; Pages: 2020
Sandhoff disease (SD) is a fatal neurodegenerative disorder belonging to the family of diseases called GM2 Gangliosidosis. There is no curative treatment of SD. The molecular pathogenesis of SD is still unclear though it is clear that the pathology i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ff74d20bac6e41734332a6629e463a
https://pubmed.ncbi.nlm.nih.gov/36360256
https://pubmed.ncbi.nlm.nih.gov/36360256
Publikováno v:
Molecular Genetics and Metabolism. 138:107193
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b59513f8dd3c6676c4819b59a9ec42
https://doi.org/10.1016/j.ymgme.2022.107193
https://doi.org/10.1016/j.ymgme.2022.107193
Autor:
Vishal Swaminathan, Prashant Chandrasekaran, Sowmya Jayachandran, Kiran Musunuru, David B. Frank, Apeksha Dave, Tiankun Wang, Brandon White, Heather A. Hartman, Sourav Bose, Rajan Jain, Haiying Li, Felix De Bie, Meghana V. Kashyap, Philip W. Zoltick, William H. Peranteau, Pallavi Menon, Kshitiz Singh, Shiva S. Teerdhala
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
In utero base editing has the potential to correct disease-causing mutations before the onset of pathology. Mucopolysaccharidosis type I (MPS-IH, Hurler syndrome) is a lysosomal storage disease (LSD) affecting multiple organs, often leading to early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6f3e77c2cfd338eb9e98b94b10a46a
https://doi.org/10.1038/s41467-021-24443-8
https://doi.org/10.1038/s41467-021-24443-8
Publikováno v:
2020 2nd International Conference on Advances in Computing, Communication Control and Networking (ICACCCN).
Vehicular ad hoc networks (VANETs) is a class of Mobile ad hoc networks (MANETs). The vehicles move at a high speed; hence, the network topology continuously changes with time. It’s base work for the Intelligent Transport System is promising. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09e2e82943daf75849e783f35fe39415
https://doi.org/10.1109/icacccn51052.2020.9362947
https://doi.org/10.1109/icacccn51052.2020.9362947
Autor:
Marinee Chuah, Thierry VandenDriessche, Ermira Samara-Kuko, Nisha Nair, Kshitiz Singh, Shilpita Sarcar, Melvin Y Rincon, Hanneke Evens
Publikováno v:
Molecular Therapy
In vivo tissue-specific genome editing at the desired loci is still a challenge. Here, we report that AAV9-delivery of truncated guide RNAs (gRNAs) and Cas9 under the control of a computationally designed hepatocyte-specific promoter lead to liver-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68bdd7332251bfd63a523f51d2b5bc38
https://doi.org/10.1016/j.ymthe.2018.02.023
https://doi.org/10.1016/j.ymthe.2018.02.023
Autor:
Reddy Ravikanth, Jyotin Kshitiz Singh, Anegh Pavithran, Anoop Pilar, Anush Nagotu, Parthasarathi Sarkar, S Sandeep, Denver Steven Pinto, Mathew David, John Joshy, Manu Jacob Abraham, Ashok Alapati, Robert Patrick Selvam, Sunil Mathew
Publikováno v:
Apollo Medicine, Vol 15, Iss 2, Pp 79-87 (2018)
All sports come with a risk of injury, and in general, the more contact involved in the sports, the higher the risk of a more significant or traumatic injury. The most frequent types of sports injuries are sprains (ligament injuries), strains (muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::ea17847123974536335bc241f52b29a9
http://www.apollomedicine.org/article.asp?issn=0976-0016
http://www.apollomedicine.org/article.asp?issn=0976-0016
Autor:
Heather A. Hartman, Nicholas J. Ahn, Deepthi Alapati, Kiran Musunuru, Jeremy Katzen, Avery C. Rossidis, Hiaying Li, Michael F. Beers, Edward E. Morrisey, Yaniv Tomer, William J. Zacharias, William H. Peranteau, Su Zhou, Barbara E. Coons, Kshitiz Singh, John D. Stratigis, Alexandra C. Chadwick
Monogenic lung diseases that are caused by mutations in surfactant genes of the pulmonary epithelium are marked by perinatal lethal respiratory failure or chronic diffuse parenchymal lung disease with few therapeutic options. Using a CRISPR fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f962fe89ad5ef2b700d153b5cdf19ac9
https://europepmc.org/articles/PMC6822403/
https://europepmc.org/articles/PMC6822403/