Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kshitiz Chaudhary"'
Autor:
Joyce C Yang, Ramana Madupu, A Scott Durkin, Nathan A Ekborg, Chandra S Pedamallu, Jessica B Hostetler, Diana Radune, Bradley S Toms, Bernard Henrissat, Pedro M Coutinho, Sandra Schwarz, Lauren Field, Amaro E Trindade-Silva, Carlos A G Soares, Sherif Elshahawi, Amro Hanora, Eric W Schmidt, Margo G Haygood, Janos Posfai, Jack Benner, Catherine Madinger, John Nove, Brian Anton, Kshitiz Chaudhary, Jeremy Foster, Alex Holman, Sanjay Kumar, Philip A Lessard, Yvette A Luyten, Barton Slatko, Nicole Wood, Bo Wu, Max Teplitski, Joseph D Mougous, Naomi Ward, Jonathan A Eisen, Jonathan H Badger, Daniel L Distel
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6085 (2009)
Here we report the complete genome sequence of Teredinibacter turnerae T7901. T. turnerae is a marine gamma proteobacterium that occurs as an intracellular endosymbiont in the gills of wood-boring marine bivalves of the family Teredinidae (shipworms)
Externí odkaz:
https://doaj.org/article/5907ccecd73a42778790741821df937f
Autor:
Sanjay Kumar, Kshitiz Chaudhary, Jeremy M Foster, Jacopo F Novelli, Yinhua Zhang, Shiliang Wang, David Spiro, Elodie Ghedin, Clotilde K S Carlow
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1189 (2007)
We report results from the first genome-wide application of a rational drug target selection methodology to a metazoan pathogen genome, the completed draft sequence of Brugia malayi, a parasitic nematode responsible for human lymphatic filariasis. Mo
Externí odkaz:
https://doaj.org/article/1ecfd8f6c9a14b828ce7f8c686abce52
Autor:
Julie Canovas, Clotilde K. S. Carlow, Catherine L. Madinger, Kshitiz Chaudhary, Paul Kelly, Jack S. Benner, Jonathan Hodgkin, Jacopo F. Novelli
Publikováno v:
Developmental Biology. 335:340-355
Galactofuranose (Galf), the furanoic form of d -galactose produced by UDP-galactopyranose mutases (UGMs), is present in surface glycans of some prokaryotes and lower eukaryotes. Absence of the Galf biosynthetic pathway in vertebrates and its importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575855e44e0e7e04bc0ffa386a9df764
https://doi.org/10.1016/j.ydbio.2009.09.010
https://doi.org/10.1016/j.ydbio.2009.09.010
Publikováno v:
Journal of Biological Chemistry. 281:25652-25658
Purine nucleoside phosphorylase (PNP) is an important component of the nucleotide salvage pathway in apicomplexan parasites and a potential target for drug development. The intracellular pathogen Toxoplasma gondii was therefore tested for sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd6dd97ec40cb36e7e8e9239c06f986
https://doi.org/10.1074/jbc.m602624200
https://doi.org/10.1074/jbc.m602624200
Autor:
Buddy Ullman, David S. Roos, Kshitiz Chaudhary, Robert G. K. Donald, Darrick Carter, Manami Nishi
Publikováno v:
Journal of Biological Chemistry. 280:22053-22059
A unique feature of the Toxoplasma gondii purine salvage pathway is the expression of two isoforms of the hypoxanthine-xanthine-guanine phosophoribosyltransferase (HXGPRT) of the parasite encoded by a single genetic locus. These isoforms differ in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9b0c76852dcc99c895457d0dd565e1
https://doi.org/10.1074/jbc.m503178200
https://doi.org/10.1074/jbc.m503178200
Autor:
E. R. Pfefferkorn, Buddy Ullman, John A. Darling, David S. Roos, Leah M. Fohl, Robert G. K. Donald, William J. Sullivan, Kshitiz Chaudhary
Publikováno v:
Journal of Biological Chemistry. 279:31221-31227
We have exploited a variety of molecular genetic, biochemical, and genomic techniques to investigate the roles of purine salvage enzymes in the protozoan parasite Toxoplasma gondii. The ability to generate defined genetic knockouts and target transge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6846ad896832f5eca0335ad973d047
https://doi.org/10.1074/jbc.m404232200
https://doi.org/10.1074/jbc.m404232200
Publikováno v:
International Journal for Parasitology. 33:1537-1544
A forkhead transcription factor gene, fktf-1, which we propose to be orthologous to the Caenorhabditis elegans dauer-regulatory gene daf-16 has been discovered in the parasitic nematode Strongyloides stercoralis. Genomic and cDNA sequences from both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be39036d1b06d978cc8efbeca400cb3d
https://doi.org/10.1016/s0020-7519(03)00205-4
https://doi.org/10.1016/s0020-7519(03)00205-4
As obligate intracellular parasites, the Apicomplexa must acquire nutrients from their hosts. Amongst the most important nutrients are purines and pyrimidines that form the essential building blocks for nucleic acids and molecules required for energy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e2eeea285079566061a162f7b98d2bc
https://doi.org/10.1016/b978-0-12-396481-6.00020-9
https://doi.org/10.1016/b978-0-12-396481-6.00020-9
Autor:
James W. Ajioka, Daniel Ajzenberg, James Alexander, Takashi Asai, Matthew Bogyo, John C. Boothroyd, Barbara A. Butcher, David J. Bzik, Vern B. Carruthers, Marie-France Cesbron-Delauw, Kshitiz Chaudhary, Isabelle Coppens, Marie-Laure Dardé, Eric Y. Denkers, Jitender P. Dubey, Jean-François Dubremetz, Jean E. Feagin, David J.P. Ferguson, Barbara A. Fox, Ricardo T. Gazzinelli, Uwe Gross, Marc-Jan Gubbels, Sandra K. Halonen, Omar S. Harb, Fiona L. Henriquez, Andrea Honda, Christopher A. Hunter, Damien Jacot, Farzana Khaliq, Imtiaz A. Khan, Kami Kim, Laura J. Knoll, Paul Latkany, Maryse Lebrun, David S. Lindsay, Carsten G.K. Lüder, Rima McLeod, Markus Meissner, José G. Montoya, Dana G. Mordue, Silvia N.J. Moreno, Naomi Morrissette, Jeremi Mullins, Eri Ochiai, Douglas A. Pace, Marilyn Parsons, Lucas Borges Pereira, Eskild Petersen, Sheela Prasad, Joshua B. Radke, Michael L. Reese, Utz Reichard, Craig W. Roberts, David S. Roos, Qila Sa, Frank Seeber, Lilach Sheiner, L. David Sibley, Anthony P. Sinai, Dominique Soldati-Favre, Boris Striepen, Emily Su, Chunlei Su, William J. Sullivan, Yasuhiro Suzuki, Stanislas Tomavo, Tadakimi Tomita, Christine Van Tubbergen, Gary Ward, Jonathan M. Wastling, Louis M. Weiss, Michael W. White, Dong Xia, Robert Yolken
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45d0d921cc429537b50463f91c2702bf
https://doi.org/10.1016/b978-0-12-396481-6.01002-3
https://doi.org/10.1016/b978-0-12-396481-6.01002-3
Autor:
David S. Roos, Kshitiz Chaudhary
Publikováno v:
Nature Biotechnology
Comparing the metabolic pathways of parasites and their hosts facilitates the identification of new drug targets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e9c3451b86905e6aee4c882a946540
https://doi.org/10.1038/nbt0905-1089
https://doi.org/10.1038/nbt0905-1089