Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kshitija, Dhuna"'
Publikováno v:
Purinergic Signalling.
The activation of P2X7 is a well-known stimulus for the NLRP3-caspase 1 inflammasome and subsequent rapid IL-1β secretion from monocytes and macrophages. Here we show that positive allosteric modulators of P2X7, ginsenosides, can enhance the release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a06cc3d170d21db0a2e9e82c69e5b4
https://doi.org/10.1007/s11302-023-09935-0
https://doi.org/10.1007/s11302-023-09935-0
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Adenosine 5′-triphosphate is a well-known extracellular signaling molecule and neurotransmitter known to activate purinergic P2X receptors. Information has been elucidated about the structure and gating of P2X channels following the determination o
Externí odkaz:
https://doaj.org/article/f86b15d565184928947460be9f6f3e84
Autor:
Vikram, Dhuna, Kshitija, Dhuna, Jatinder, Singh, Kumar, Saxena Ajit, Kumar, Agrawal Satyam, Singh, Kamboj Sukhdev
Publikováno v:
In Pharmacognosy Journal May 2010 2(9):266-277
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 12, Pp 1-16 (2019)
Cell Death and Disease, Vol 10, Iss 12, Pp 1-16 (2019)
P2X7 is an ATP-gated ion channel that is highly expressed by leukocytes, such as macrophages. Here, P2X7 has been demonstrated to be involved in the regulation of various cell death pathways; including apoptosis, pyroptosis, necrosis, and autophagy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a3e7f3a455f594d8db670dc3643bc1
https://pubmed.ncbi.nlm.nih.gov/31767863
https://pubmed.ncbi.nlm.nih.gov/31767863
Autor:
Vikram Dhuna, Muhammad Monim-ul-Mehboob, Kshitija Dhuna, L. Li, Anvarhusein A. Isab, Manzar Sohail, Mohammed I.M. Wazeer, Adam A.A. Seliman, Gaurav Bhatia, Muhammad Altaf
Publikováno v:
European Journal of Medicinal Chemistry. 95:464-472
Two new gold(I) complexes that contain tri-ter-butylphosphine and dialkyl dithiocarbamate ligands were synthesized and characterized by FTIR, NMR spectroscopy, Cyclic voltammetry, elemental analysis and X-ray diffraction. The in vitro cytotoxicity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91f63ecd8fd9a611adae0e017529b26
https://doi.org/10.1016/j.ejmech.2015.03.019
https://doi.org/10.1016/j.ejmech.2015.03.019
Autor:
Charlie Xue, Ji-Ming Ye, Ray Helliwell, Charlene ShioukHuey, Juan C. Molero, Leanne Stokes, Kshitija Dhuna
Publikováno v:
British Journal of Pharmacology. 172:3326-3340
Background and Purpose The P2X7 receptor is an ATP-gated ion channel predominantly expressed in immune cells and plays a key role in inflammatory processes. Ginseng is a well-known Chinese herb with both pro- and anti-inflammatory properties and many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e31034b41f1ec0b6ea8800558d64b0e
https://doi.org/10.1111/bph.13123
https://doi.org/10.1111/bph.13123
Autor:
Anvarhusein A. Isab, Muhammad Altaf, Vikram Dhuna, Kshitija Dhuna, Gaurav Bhatia, Saleh Altuwaijri, Muhammad Monim-ul-Mehboob
Publikováno v:
New Journal of Chemistry. 39:377-385
A new series of mononuclear [t-Bu3PAuS2CN(C7H7)2] (1), and binuclear [(DPPM)Au2(S2CN(CH3)2)2] (2), [(DPPM)Au2(S2CN(C2H5)2)2] (3) and [(DPPM)Au2(S2CN(C7H7)2)2] (4) [where DPPM = 1,1-bis(diphenylphosphino)methane, S2CN(CH3)2 = dimethyldithiocarbamate,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e05c01e712b9b832596ef85a58f88cf
https://doi.org/10.1039/c4nj00747f
https://doi.org/10.1039/c4nj00747f
Autor:
Leanne Stokes, Luba Sominsky, Kshitija Dhuna, Sarah J. Spencer, Ilvana Ziko, S.N. De Luca, Mary Tolcos
Publikováno v:
Journal of neuroendocrinology. 29(11)
The early-life period is extremely vulnerable to programming effects from the environment, many of which persist into adulthood. We have previously demonstrated that adult rats overfed as neonates have hypothalamic microglia that are hyper-responsive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db412630ae5c5804240136c2c031fcdc
https://pubmed.ncbi.nlm.nih.gov/28983991
https://pubmed.ncbi.nlm.nih.gov/28983991
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 8 (2017)
Frontiers in Pharmacology, Vol 8 (2017)
Adenosine 5′-triphosphate is a well-known extracellular signaling molecule and neurotransmitter known to activate purinergic P2X receptors. Information has been elucidated about the structure and gating of P2X channels following the determination o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d76df2f3ddc6994166340df22c7756
https://doi.org/10.3389/fphar.2017.00291
https://doi.org/10.3389/fphar.2017.00291
Autor:
Muhammad Monim-ul-Mehboob, Vikram Dhuna, Muhammad Altaf, Kshitija Dhuna, Adam A.A. Seliman, Gaurav Bhatia, Anvarhusein A. Isab
Publikováno v:
Journal of Organometallic Chemistry. 765:68-79
Three new linear gold(I) complexes of the formulas [(Ipr)Au(S2CN(CH3)2)] (1), [(Ipr)Au (S2CN(C2H5)2)] (2) and [(Ipr)Au(S2CN(C7H7)2)] (3) [where Ipr = 1,3-bis(2,6-di-isopropylphenyl)imidazol-2-ylidenegold] have been prepared by the reaction of equimol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82b04489891fdd034d4786a4fa74f2cc
https://doi.org/10.1016/j.jorganchem.2014.04.029
https://doi.org/10.1016/j.jorganchem.2014.04.029