Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kshatresh D. Dubey"'
Autor:
Savio Cardoza, Anirudh Singh, Souvik Sur, Mintu Singh, Kshatresh D. Dubey, Sintu Kumar Samanta, Ajay Mandal, Vibha Tandon
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36786- (2024)
Remdesivir, a C-nucleotide prodrug binds to the viral RNA-dependent-RNA polymerase (RdRp) and inhibits the viral replication by terminating RNA transcription prematurely. It is reported in literature that interaction between the C-1’β–CN moiety
Externí odkaz:
https://doaj.org/article/1b582576a4fe40eda6dbfc8e99660a2b
Autor:
Aitao Li, Binju Wang, Adriana Ilie, Kshatresh D. Dubey, Gert Bange, Ivan V. Korendovych, Sason Shaik, Manfred T. Reetz
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
The majority of enzymatic Kemp elimination reactions proceed via a well-established acid-base mechanism. Here, the authors show that cytochrome P450 is able to metabolize the leflunomide drug via a redox Kemp elimination, offering new insights into e
Externí odkaz:
https://doaj.org/article/aa51e79cc994447a82719af128acff74
Scientists are rigorously looking for an efficient vaccine against the current pandemic due to the SARS-CoV-2 virus. The reverse vaccinology approach may provide us with significant therapeutic leads in this direction and further determination of T-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0338285815b6bbfec9521d91808ecb3a
