Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ksenija Slavic-Obradovic"'
Autor:
Catarina Pinto, Ksenija Slavic-Obradovic, Daniela Fürweger, Barbara Thaler, Abdallah Souabni, Sebastian Carotta, Martin Aichinger, Ulrich Reiser, Maria Antonietta Impagnatiello, Iñigo Tirapu
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106381- (2023)
Summary: Small molecule IAP antagonists - SMAC mimetics (SM) - are being developed as an anticancer therapy. SM therapy was demonstrated not only to sensitize tumor cells to TNFα-mediated cell death but also to exert immunostimulatory properties. Th
Externí odkaz:
https://doaj.org/article/68266ad8652247818e6f91fc5012f708
Autor:
Daniel Gerlach, Markus Schaefer, Sabine Olt, Ulrike Tontsch-Grunt, Sebastian Carotta, Rebecca Langlois, Martin Aichinger, Sarah Rieser, Maria Antonietta Impagnatiello, Norbert Kraut, Johannes Zuber, Valeria Santoro, Andreas Wernitznig, Sabine Kallenda, Daniel Zach, Julian Jude, Martina Weissenboeck, Thomas Zichner, Melanie Talata De Almeida, Andrea Neudolt, Ksenija Slavic-Obradovic, Andreas Schlattl, Dirk Scharn, Martina Sykora, Markus Reschke, Michaela Fellner, Stefanie Ruhland, Florian Ebner, Juergen Moll, Carina Salomon
Publikováno v:
Cancer Research. 80:6221-6221
Background: Engagement of Tumor Necrosis Factor-α (TNF-α) with its receptor can lead to dramatically different cellular outcomes ranging from regulating cell survival and inflammation to induction of programmed forms of cell death. A critical proxi