Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Ksenija, Nesic"'
Autor:
Ksenija Nesic, John J. Krais, Yifan Wang, Cassandra J. Vandenberg, Pooja Patel, Kathy Q. Cai, Tanya Kwan, Elizabeth Lieschke, Gwo-Yaw Ho, Holly E. Barker, Justin Bedo, Silvia Casadei, Andrew Farrell, Marc Radke, Kristy Shield-Artin, Jocelyn S. Penington, Franziska Geissler, Elizabeth Kyran, Robert Betsch, Lijun Xu, Fan Zhang, Alexander Dobrovic, Inger Olesen, Rebecca Kristeleit, Amit Oza, Iain McNeish, Gayanie Ratnayake, Nadia Traficante, Australian Ovarian Cancer Study, Anna DeFazio, David D. L. Bowtell, Thomas C. Harding, Kevin Lin, Elizabeth M. Swisher, Olga Kondrashova, Clare L. Scott, Neil Johnson, Matthew J. Wakefield
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract PARP inhibitor (PARPi) therapy has transformed outcomes for patients with homologous recombination DNA repair (HRR) deficient ovarian cancers, for example those with BRCA1 or BRCA2 gene defects. Unfortunately, PARPi resistance is common. Mul
Externí odkaz:
https://doaj.org/article/8f0a9b712db94dd79db01d43d570add9
Autor:
Franziska Geissler, Ksenija Nesic, Olga Kondrashova, Alexander Dobrovic, Elizabeth M. Swisher, Clare L. Scott, Matthew J. Wakefield
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Epigenetic alterations, including aberrant DNA methylation, are now recognized as bone fide hallmarks of cancer, which can contribute to cancer initiation, progression, therapy responses and therapy resistance. Methylation of gene promoters can have
Externí odkaz:
https://doaj.org/article/149fbe6f4eb449958647e023e6a32ed0
Autor:
Genevieve Dall, Cassandra J. Vandenberg, Ksenija Nesic, Gayanie Ratnayake, Wenying Zhu, Joseph H. A. Vissers, Justin Bedő, Jocelyn Penington, Matthew J. Wakefield, Damien Kee, Amandine Carmagnac, Ratana Lim, Kristy Shield-Artin, Briony Milesi, Amanda Lobley, Elizabeth L. Kyran, Emily O’Grady, Joshua Tram, Warren Zhou, Devindee Nugawela, Kym Pham Stewart, Reece Caldwell, Lia Papadopoulos, Ashley P. Ng, Alexander Dobrovic, Stephen B. Fox, Orla McNally, Jeremy D. Power, Tarek Meniawy, Teng Han Tan, Ian M. Collins, Oliver Klein, Stephen Barnett, Inger Olesen, Anne Hamilton, Oliver Hofmann, Sean Grimmond, Anthony T. Papenfuss, Clare L. Scott, Holly E. Barker
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)
Abstract Background Uterine leiomyosarcoma (uLMS) is a rare and aggressive gynaecological malignancy, with individuals with advanced uLMS having a five-year survival of 0.2) but only two samples had a CHORD score > 50%, one of which had a homozygous
Externí odkaz:
https://doaj.org/article/90697e9e0fe04ca583a35a4167337ba8
Autor:
Gwo Yaw Ho, Cassandra J. Vandenberg, Ratana Lim, Elizabeth L. Christie, Dale W. Garsed, Elizabeth Lieschke, Ksenija Nesic, Olga Kondrashova, Gayanie Ratnayake, Marc Radke, Jocelyn S. Penington, Amandine Carmagnac, Valerie Heong, Elizabeth L. Kyran, Fan Zhang, Nadia Traficante, Ruby Huang, Alexander Dobrovic, Elizabeth M. Swisher, Orla McNally, Damien Kee, Matthew J. Wakefield, Anthony T. Papenfuss, David D. L. Bowtell, Holly E. Barker, Clare L. Scott
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: Despite initial response to platinum-based chemotherapy and PARP inhibitor therapy (PARPi), nearly all recurrent high-grade serous ovarian cancer (HGSC) will acquire lethal drug resistance; indeed, ~15% of individuals have de novo platinu
Externí odkaz:
https://doaj.org/article/acfd52763fdb4a6092abd9806478e071
Publikováno v:
Archives of Veterinary Medicine, Vol 16, Iss 1 (2023)
Corn wet distillers grains with solubles (WDGS) included up to 25% in the diet of 16 Simmental dairy cows, 27 to 72 months old, during three weeks, negatively affected rumen function monitored by non-invasive parameters, such as fecal consistency, an
Externí odkaz:
https://doaj.org/article/ca1bc27612d345a0b5e10df8b284795e
Autor:
Bozidar Savic, Oliver Radanovic, Vesna Milicevic, Branislav Kureljusic, Nemanja Zdravkovic, Ksenija Nesic, Ognjen Stevancevic
Publikováno v:
Veterinární Medicína, Vol 65, Iss 11, Pp 480-486 (2020)
There are limited data available in the literature about the frequency and distribution of endocarditis in suckling and weaned piglets. The goal of this study was to investigate the frequency and distribution of lesions from cases of spontaneous valv
Externí odkaz:
https://doaj.org/article/9f277b58962b4fbdbc7c855fe4ffc460
Autor:
Ksenija Nesic, Sandra Jaksic, Nenad Popov, Milica Zivkov-Balos, Marko Pajic, Bojan Zloh, Vladimir Polacek
Publikováno v:
Archives of Veterinary Medicine, Vol 13, Iss 1 (2020)
The contamination of animal feed with mycotoxins is a worldwide problem in the animal husbandry, but it also represents a serious threat for the whole food chain. The health of both animals and humans is potentially endangered. From this point of vie
Externí odkaz:
https://doaj.org/article/302f30680ba249e69ba14843342726ce
Autor:
Olga Kondrashova, Monique Topp, Ksenija Nesic, Elizabeth Lieschke, Gwo-Yaw Ho, Maria I. Harrell, Giada V. Zapparoli, Alison Hadley, Robert Holian, Emma Boehm, Valerie Heong, Elaine Sanij, Richard B. Pearson, John J. Krais, Neil Johnson, Orla McNally, Sumitra Ananda, Kathryn Alsop, Karla J. Hutt, Scott H. Kaufmann, Kevin K. Lin, Thomas C. Harding, Nadia Traficante, Australian Ovarian Cancer Study (AOCS), Anna deFazio, Iain A. McNeish, David D. Bowtell, Elizabeth M. Swisher, Alexander Dobrovic, Matthew J. Wakefield, Clare L. Scott
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Around 10% of high-grade serous ovarian carcinomas (HGSOC) harbor BRCA1 promoter methylation, but it is uncertain how it predicts response to PARP inhibition. Here, the authors show that homozygous BRCA1 methylation predicts response to rucaparib whi
Externí odkaz:
https://doaj.org/article/daa72fc740814394b7993401524f3f72
Autor:
Clare L. Scott, Matthew J. Wakefield, Alexander Dobrovic, Scott H. Kaufmann, Nicola Waddell, Katia Nones, S. John Weroha, Elizabeth M. Swisher, David D.L. Bowtell, Anna DeFazio, Australian Ovarian Cancer Study, Nadia Traficante, Orla McNally, Inger Olesen, Damien Kee, Maria I. Harrell, Mohammad Reza Eftekhariyan Ghamsari, Zi Qing Chai, Ashan Musafer, Marc Radke, Kristy Shield-Artin, Nirashaa Bound, Genevieve Dall, Elizabeth Lieschke, Gwo-Yaw Ho, Cassandra J. Vandenberg, Cordelia D. McGehee, Rachel M. Hurley, Olga Kondrashova, Ksenija Nesic
In high-grade serous ovarian carcinoma (HGSC), deleterious mutations in DNA repair gene RAD51C are established drivers of defective homologous recombination and are emerging biomarkers of PARP inhibitor (PARPi) sensitivity. RAD51C promoter methylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e56ea8d4ae85dde3e5f8a4e6285a8fd
https://doi.org/10.1158/0008-5472.c.6513498
https://doi.org/10.1158/0008-5472.c.6513498
Autor:
Clare L. Scott, Matthew J. Wakefield, Alexander Dobrovic, Scott H. Kaufmann, Nicola Waddell, Katia Nones, S. John Weroha, Elizabeth M. Swisher, David D.L. Bowtell, Anna DeFazio, Australian Ovarian Cancer Study, Nadia Traficante, Orla McNally, Inger Olesen, Damien Kee, Maria I. Harrell, Mohammad Reza Eftekhariyan Ghamsari, Zi Qing Chai, Ashan Musafer, Marc Radke, Kristy Shield-Artin, Nirashaa Bound, Genevieve Dall, Elizabeth Lieschke, Gwo-Yaw Ho, Cassandra J. Vandenberg, Cordelia D. McGehee, Rachel M. Hurley, Olga Kondrashova, Ksenija Nesic
All Supplementary Methods for the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72057a47e3c29c834e15f851c84579c8
https://doi.org/10.1158/0008-5472.22429956
https://doi.org/10.1158/0008-5472.22429956