Výsledky vyhledávání - "Ksenia Shestakova"

Autor: Ksenia Shestakova

Publikováno v: Portraits of Women in International Law ISBN: 0198868456

Recent centenaries of equal women’s rights to practice law, equal voting rights, and the 1917 Russian Revolutions revived scholars’ interest in the early twentieth century. Helene Halperin-Ginsburg, the first woman international legal scholar in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec1b25b7367c842d18126912e5a68f09
https://doi.org/10.1093/oso/9780198868453.003.0041

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Pharmacokinetic Properties of the Novel Synthetic Cannabinoid 5F-APINAC and Its Influence on Metabolites Associated with Neurotransmission in Rabbit Plasma

Autor: Alex Brito, Pavel A. Markin, Natalia L. Bochkareva, Alexey Kukharenko, Andrey Anatolievich Nedorubov, Natalia V. Mesonzhnik, Roman M. Kuznetsov, Alexey V Lyundup, Natalia E. Moskaleva, Franco Tagliaro, Ksenia Shestakova, Elizaveta G Appolonova, Svetlana A. Appolonova

Publikováno v: Pharmaceuticals
Volume 14
Issue 7
Pharmaceuticals, Vol 14, Iss 668, p 668 (2021)

The strong psychoactive effects of synthetic cannabinoids raise the need for the deeper studying of their neurometabolic effects. The pharmacokinetic properties of 5F-APINAC and its influence on metabolomics profiles associated with neurotransmission

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0901362882ff60a448a3dacae924b8

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A novel low-cost approach for the semi-quantitative analysis of carbohydrate-deficient transferrin (CDT) based on fluorescence resonance energy transfer (FRET)

Autor: S. A. Savchuk, Federica Bortolotti, Franco Tagliaro, Ksenia Shestakova, Elio Franco De Palo, Giacomo Musile

Publikováno v: Clinica Chimica Acta. 495:556-561

The increase of the carbohydrate-deficient transferrin (CDT) as results of an heavy intake of alcohol for at least two weeks, is a well-known biochemical modification since the middle '70s. Notwithstanding the first commercial kit for the diagnosis o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234dfced48bceb2bf5d9f4426352c05d
https://doi.org/10.1016/j.cca.2019.06.003

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Development of a low cost gas diffusion device for ammonia detection in the vitreous humor and its preliminary application for estimation of the time since death

Autor: Giacomo Musile, Ksenia Shestakova, Franco Tagliaro, Elio Franco De Palo, Rossella Gottardo, Covadonga Palacio, Dario Raniero

Publikováno v: Forensic Science International. 295:150-156

A simple and low cost analytical device is described for the determination of ammonium in the vitreous humor suitable for inferring the post mortem interval in forensic cases. The device is based on ammonia formation from ammonium ion by means of NaO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502e51273c2581fcaa5cec188ba91ffd
https://doi.org/10.1016/j.forsciint.2018.12.012

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In Vivo Targeted Metabolomic Profiling of Prostanit, a Novel Anti-PAD NO-Donating Alprostadil-Based Drug

Autor: Igor V. Serkov, Igor I Lyubimov, Svetlana A. Appolonova, Natalia E. Moskaleva, Fomina-Ageeva Ev, Natalia V. Mesonzhnik, Alexey Kukharenko, Vladimir V. Bezuglov, M. G. Akimov, Ksenia Shestakova

Publikováno v: Molecules, Vol 25, Iss 5896, p 5896 (2020)
Molecules
Volume 25
Issue 24

Prostanit is a novel drug developed for the treatment of peripheral arterial diseases. It consists of a prostaglandin E1 (PGE1) moiety with two nitric oxide (NO) donor fragments, which provide a combined vasodilation effect on smooth muscles and vasc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b96b00f23caea462be464eb40f94ff3
https://www.mdpi.com/1420-3049/25/24/5896

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In vivo and in vitro metabolism of the novel synthetic cannabinoid 5F-APINAC

Autor: Pavel A. Markin, Dmitry Burmykin, S. A. Savchuk, Franco Tagliaro, Natalia V. Mesonzhnik, Covadonga Palacio, Alex Brito, Natalia L. Bochkareva, Roman M. Kuznetsov, Maxim Ovcharov, Svetlana A. Appolonova, Ksenia Shestakova, Giacomo Musile

New generations of synthetic cannabinoids (SCs) have recognized strong psychoactive effects, rapidly becoming potent drugs of abuse. Characterization of metabolites associated with SCs is useful for their subsequent detection in biological samples. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0149c328cb685dd5567b12d608b27719
http://hdl.handle.net/11562/1010193

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LC-MS/MS Identification and Structural Characterization of Main Biodegradation Products of Nitroproston - A Novel Prostaglandin-based Pharmaceutical Compound

Autor: Pavel A. Baranov, Igor I Lyubimov, Igor V. Serkov, Vladimir V. Bezuglov, Natalia V. Mesonzhnik, Ksenia Shestakova, Svetlana A. Appolonova, Ksenya O Kurynina, Natalia E. Moskaleva, Natalia Gretskaya

Publikováno v: Drug Metabolism Letters. 12:54-61

Background Nitroproston is a novel prostaglandin-based compound modified by NOdonating groups with potential application in obstructive respiratory diseases such as asthma and obstructive bronchitis. Nitroproston has been extensively studied using va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbdffba18612adc0e4d62029b87d076
https://doi.org/10.2174/1872312812666180309160927

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Procedure for setting control for the turnover of new, potentially hazardous psychoactive substances. Detection of metabolites of a new APINAC psychoactive compound in rat urine by gas and liquid chromatography with mass spectrometry detection

Autor: N. V. Samyshkina, S. A. Savchuk, Svetlana A. Appolonova, V. N. Unizhaev, O. S. Gorina, O. M. Kogdas, Ksenia Shestakova, L. N. Rizvanova

Publikováno v: Journal of Analytical Chemistry. 72:1193-1202

The appearance of a new APINAC compound (AKB-57, ACBL(N)-018, adamantan-1-yl-1-pentyl-1H-indazol-3-carboxylate) in the Russian market of psychoactive drugs led to the need in setting measures of state control over its turnover and in solving the prob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::88bdac21bb927c87ea571fee227ef0da
https://doi.org/10.1134/s1061934817110089

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In vivo metabolism of the new synthetic cannabinoid APINAC in rats by GC–MS and LC–QTOF-MS

Autor: Alexander Pechnikov, Ksenia Shestakova, Svetlana A. Appolonova, S. A. Savchuk, Franco Tagliaro, Liliay Rizvanova

Publikováno v: Forensic Toxicology. 35:359-368

The recent appearance of APINAC (AKB-57, ACBL(N)-018, adamantan-1-yl 1-pentyl-1H-indazole-3-carboxylate) in the market of the so-called novel psychoactive substances resulted in the need of defining its characteristics and searching its metabolites f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a44b51ce9e365bc8477c7847d0f31426
https://doi.org/10.1007/s11419-017-0364-y

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Thanatochemistry at the crime scene: a microfluidic paper-based device for ammonium analysis in the vitreous humor

Autor: Federica Bortolotti, Giacomo Musile, Franco Tagliaro, Ksenia Shestakova, Elio Franco De Palo, Yvane Agard

Publikováno v: Analytica chimica acta. 1083

Most of the on-site approaches for inferring of the post-mortem interval are still based on observative data from the direct body inspection, whereas, objective and quantitative analyses, such as potassium in the vitreous humor, are require laborator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750e873e85f75e7ec745d2061b4a4569
https://pubmed.ncbi.nlm.nih.gov/31493805

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