Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ksenia S. Kudryashova"'
Autor:
George V. Sharonov, Oksana V. Nekrasova, Ksenia S. Kudryashova, Mikhail P. Kirpichnikov, Alexey V. Feofanov
Publikováno v:
Bioengineering, Vol 8, Iss 11, p 187 (2021)
Screening drug candidates for their affinity and selectivity for a certain binding site is a crucial step in developing targeted therapy. Here, we created a screening assay for receptor binding that can be easily scaled up and automated for the high
Externí odkaz:
https://doaj.org/article/d16d354f7ef944c1a6ecd7667f7027b7
Autor:
Oksana V. Nekrasova, Alexandra L. Primak, Anastasia A. Ignatova, Valery N. Novoseletsky, Olga V. Geras’kina, Ksenia S. Kudryashova, Sergey A. Yakimov, Mikhail P. Kirpichnikov, Alexander S. Arseniev, Alexey V. Feofanov
Publikováno v:
Toxins, Vol 12, Iss 12, p 802 (2020)
Recently developed fluorescent protein-scorpion toxin chimeras (FP-Tx) show blocking activities for potassium voltage-gated channels of Kv1 family and retain almost fully pharmacological profiles of the parental peptide toxins (Kuzmenkov et al., Sci
Externí odkaz:
https://doaj.org/article/6c6e8f2d8c2143f7a9303d4be758b138
Autor:
Ksenia S. Kudryashova, George V. Sharonov, Oksana V. Nekrasova, Mikhail P. Kirpichnikov, Alexey V. Feofanov
Publikováno v:
Bioengineering, Vol 8, Iss 187, p 187 (2021)
Bioengineering
Volume 8
Issue 11
Bioengineering
Volume 8
Issue 11
Screening drug candidates for their affinity and selectivity for a certain binding site is a crucial step in developing targeted therapy. Here, we created a screening assay for receptor binding that can be easily scaled up and automated for the high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb244e4f8202f10ad63f334d2d9bdf73
https://www.mdpi.com/2306-5354/8/11/187
https://www.mdpi.com/2306-5354/8/11/187
Autor:
Alexandra L Primak, Alexey V. Feofanov, V. N. Novoseletsky, S.A. Yakimov, Mikhail P. Kirpichnikov, Ksenia S Kudryashova, Oksana V. Nekrasova, Olga Geraskina, Alexander S. Arseniev, Anastasia A. Ignatova
Publikováno v:
Toxins
Toxins, Vol 12, Iss 802, p 802 (2020)
Volume 12
Issue 12
Toxins, Vol 12, Iss 802, p 802 (2020)
Volume 12
Issue 12
Recently developed fluorescent protein-scorpion toxin chimeras (FP-Tx) show blocking activities for potassium voltage-gated channels of Kv1 family and retain almost fully pharmacological profiles of the parental peptide toxins (Kuzmenkov et al., Sci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d89a78511213443432af2b490e2134bc
http://europepmc.org/articles/PMC7766132
http://europepmc.org/articles/PMC7766132
Publikováno v:
Proteomics. 20(5-6)
Aging results in various deleterious changes in the human body that may lead to loss of function and the manifestation of chronic diseases. While diseases can generally be reliably diagnosed, the aging process itself requires more sophisticated appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cbe1773c4cac45db455be3dfce17a9f
https://pubmed.ncbi.nlm.nih.gov/32084299
https://pubmed.ncbi.nlm.nih.gov/32084299
Publikováno v:
Ageing Research Reviews. 70:101410
Human aging is a multifactorial phenomenon that affects numerous organ systems and cellular processes, with the immune system being one of the most dysregulated. Immunosenescence, the gradual deterioration of the immune system, and inflammaging, a ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a706f303eb24514a3375cea75290bf3e
https://doi.org/10.1016/j.arr.2021.101410
https://doi.org/10.1016/j.arr.2021.101410
Publikováno v:
Biochemical Pharmacology. 190:114646
Chimeric potassium channels KcsA-Kv1, which are among the most intensively studied hybrid membrane proteins to date, were constructed by replacing a part of the pore domain of bacterial potassium channel KcsA (K channel of streptomyces A) with corres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035f0a603883d4613bac53f8c46f5a1d
https://doi.org/10.1016/j.bcp.2021.114646
https://doi.org/10.1016/j.bcp.2021.114646
Peptides from puff adder Bitis arietans venom, novel inhibitors of nicotinic acetylcholine receptors
Autor:
T. V. Andreeva, Marina V. Serebryakova, Vladislav G. Starkov, Maxim N. Zhmak, Catherine A. Vulfius, Nina V. Kopylova, Ekaterina N. Spirova, Yuri N. Utkin, Denis S. Kudryavtsev, Ksenia S. Kudryashova, Irina V. Shelukhina, Victor I. Tsetlin, Elena V. Kryukova, Igor Ivanov
Publikováno v:
Toxicon. 121:70-76
Phospholipase A2 (named bitanarin) possessing capability to block nicotinic acetylcholine receptors (nAChRs) was isolated earlier (Vulfius et al., 2011) from puff adder Bitis arietans venom. Further studies indicated that low molecular weight fractio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d82ff98b5422ed4b94660286fa7a40a
https://doi.org/10.1016/j.toxicon.2016.08.020
https://doi.org/10.1016/j.toxicon.2016.08.020