Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ksenia Krupina"'
Autor:
Ksenia Krupina, Charlotte Kleiss, Sushil Awal, Irene Rodriguez-Hernandez, Victoria Sanz-Moreno, Izabela Sumara
Publikováno v:
Molecular & Cellular Oncology, Vol 5, Iss 2 (2018)
Defects in mitosis can lead to aneuploidy, which is a common feature of human cancers. Spindle Assembly Checkpoint (SAC) controls fidelity of chromosome segregation in mitosis to prevent aneuploidy. The ubiquitin receptor protein Ubiquitin Associated
Externí odkaz:
https://doaj.org/article/503b78700e874f51816d6fd8cb5ca472
Publikováno v:
Curr Opin Cell Biol
Micronuclei are small membrane-bounded compartments with a DNA content encapsulated by a nuclear envelope and spatially separated from the primary nucleus. Micronuclei have long been linked to chromosome instability, genome rearrangements, and mutage
Autor:
Nicodème Paul, Kay Hofmann, Charlotte Kleiss, Ksenia Krupina, Sadek Fournane, Izabela Sumara, Thibaud Metzger, Jason R. Swedlow, Olivier Poch, Laurent Brino, Benoit Fischer, Wolfgang Raffelsberger, Iain M. Porter, Stephane Schmucker
Publikováno v:
Developmental Cell
Developmental Cell, Elsevier, 2016, 36 (1), pp.63-78. ⟨10.1016/j.devcel.2015.12.017⟩
Developmental cell
Developmental Cell, Elsevier, 2016, 36 (1), pp.63-78. ⟨10.1016/j.devcel.2015.12.017⟩
Developmental cell
SummaryMitosis ensures equal segregation of the genome and is controlled by a variety of ubiquitylation signals on substrate proteins. However, it remains unexplored how the versatile ubiquitin code is read out during mitotic progression. Here, we id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a284c2b563ef59b8645b30e8f68c3203
https://hal.archives-ouvertes.fr/hal-03080547
https://hal.archives-ouvertes.fr/hal-03080547
Autor:
Pascal Kessler, Carmine Settembre, Izabela Sumara, Michael Mihlan, Eric Erbs, Laura Cinque, Alexander Goginashvili, Yannick Schwab, Joëlle Morvan, Romeo Ricci, Coralie Spiegelhalter, Adrien Pasquier, Zhirong Zhang, Nicole L. Schieber, Ksenia Krupina
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2015, 347 (6224), pp.878-882. ⟨10.1126/science.aaa2628⟩
Science, American Association for the Advancement of Science, 2015, 347 (6224), pp.878-882. ⟨10.1126/science.aaa2628⟩
Pancreatic β cells lower insulin release in response to nutrient depletion. The question of whether starved β cells induce macroautophagy, a predominant mechanism maintaining energy homeostasis, remains poorly explored. We found that, in contrast t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c6ebff630836e78785c98e0c372280
https://hal.archives-ouvertes.fr/hal-03080550
https://hal.archives-ouvertes.fr/hal-03080550
Publikováno v:
Genes and Cancer
Genes and Cancer, SAGE Publications, 2013, 3 (11-12), pp.697-711. ⟨10.1177/1947601912473477⟩
Genes and Cancer, SAGE Publications, 2013, 3 (11-12), pp.697-711. ⟨10.1177/1947601912473477⟩
Conjugation of ubiquitin (ubiquitination) to substrate proteins is a widespread modification that ensures fidelity of many cellular processes. During mitosis, different dynamic morphological transitions have to be coordinated in a temporal and spatia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed57119752a7b892074166abcdc156e
https://hal.archives-ouvertes.fr/hal-03080558
https://hal.archives-ouvertes.fr/hal-03080558
Autor:
Peter Horvath, Katja Beck, Eva Laurell, Ulrike Kutay, Ruedi Aebersold, Wolfram Antonin, Gandhi Theerthagiri, Ksenia Krupina, Bernd Bodenmiller
Publikováno v:
Cell. (4):539-550
SummaryDisassembly of nuclear pore complexes (NPCs) is a decisive event during mitotic entry in cells undergoing open mitosis, yet the molecular mechanisms underlying NPC disassembly are unknown. Using chemical inhibition and depletion experiments we