Stereotactic body radiation therapy (SBRT) for early stage lung cancer delivers clinically significant radiation to the draining lymph nodes

Autor: Bhupesh, Parashar, Prabhsimranjot, Singh, Paul, Christos, Shruthi, Arora, Prashant, Desai, A Gabriella, Wernicke, Marylynn, Delamerced, Dustin, Boothe, Dattatreyudu, Nori, Ksc, Chao

Publikováno v: Journal of radiosurgery and SBRT. 2(4)

To evaluate clinically significant radiotherapy (RT) dose to draining lymph nodes (LN) in patients treated with SBRT.Early stage non-small cell lung cancer patients treated with SBRT were selected for analysis. Patients received SBRT if they were not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::19c12c3f8163043898a1b27303fb5d69
https://pubmed.ncbi.nlm.nih.gov/29296376

Inhibition of DNMTs increases neoantigen-reactive T-cell toxicity against microsatellite-stable colorectal cancer in combination with radiotherapy.

Autor: Huang KC; Department of Biomedical Imaging and Radiological Science, China Medical University, Taiwan; Translation Research Core, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan; Cancer Biology and Precision Therapeutics Center, China Medical University, Taichung 40402, Taiwan. Electronic address: chihyang0425@mail.cmu.edu.tw., Ke TW; School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan; Department of Colorectal Surgery, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan., Lai CY; Translation Research Core, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan; Center of Proton therapy and Science, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan., Hong WZ; Translation Research Core, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan; Center of Proton therapy and Science, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan., Chang HY; Translation Research Core, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan; Center of Proton therapy and Science, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan., Lee CY; Innovation Frontier Institute of Research for Science and Technology, National Taipei University of Technology, Taipei 106344, Taiwan; Department of Electrical Engineering, National Taipei University of Technology, Taipei 106344, Taiwan., Wu CH; Center of Proton therapy and Science, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan; Bioinformatics and Biostatistics Core, Centers of Genomic and Precision Medicine, National Taiwan University, Taipei 10055, Taiwan., Chiang SF; Lab of Precision Medicine, Feng-Yuan Hospital, Taichung 42055, Taiwan., Liang JA; Department of Radiation Oncology, School of Medicine, China Medical University, Taichung 40402, Taiwan; Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan., Chen JY; Department of Biomedical Imaging and Radiological Science, China Medical University, Taiwan; Translation Research Core, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan., Yang PC; Center of Proton therapy and Science, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan., Chen WT; Department of Colorectal Surgery, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan; Department of Surgery, School of Medicine, China Medical University, Taichung 40402, Taiwan; Department of Colorectal Surgery, China Medical University HsinChu Hospital, China Medical University, Hsinchu 302, Taiwan., Chuang EY; Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan; Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu, Taiwan., Chao KSC; Center of Proton therapy and Science, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan; Department of Radiation Oncology, School of Medicine, China Medical University, Taichung 40402, Taiwan; Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan. Electronic address: biotechgateway@gmail.com.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Aug; Vol. 177, pp. 116958. Date of Electronic Publication: 2024 Jun 24.

Colorectal cancer-specific IFNβ delivery overcomes dysfunctional dsRNA-mediated type I interferon signaling to increase the abscopal effect of radiotherapy.

Autor: Huang KC; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan flylerd0425@gmail.com d94032@mail.cmuh.org.tw.; Translation Research Core, China Medical University Hospital, Taichung, Taiwan.; Cancer Biology and Precision Therapeutics Center, China Medical University, Taichung, Taiwan., Chiang SF; Lab of Precision Medicine, Feng-Yuan Hospital Ministry of Health and Welfare, Taichung, Taiwan., Chang HY; Translation Research Core, China Medical University Hospital, Taichung, Taiwan.; Proton Cancer, China Medical University Hospital, Taichung, Taiwan., Hong WZ; Proton Cancer, China Medical University Hospital, Taichung, Taiwan., Chen JY; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan.; Translation Research Core, China Medical University Hospital, Taichung, Taiwan.; Proton Cancer, China Medical University Hospital, Taichung, Taiwan., Lee PC; Cancer Biology and Precision Therapeutics Center, China Medical University, Taichung, Taiwan.; Graduate Institute of Biomedical Science, China Medical University, Taichung, Taiwan., Liang JA; Department of Radiation Oncology, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, China Medical University, Taichung, Taiwan., Ke TW; Department of Colorectal Cancer, China Medical University Hospital, Taichung, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan., Peng SL; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan., Shiau AC; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan.; Proton Cancer, China Medical University Hospital, Taichung, Taiwan.; Department of Radiation Oncology, China Medical University Hospital, Taichung, Taiwan., Chen TW; Department of Pathology, Asia University, Taichung, Taiwan., Yang PC; Proton Cancer, China Medical University Hospital, Taichung, Taiwan., Chen WT; School of Medicine, China Medical University, Taichung, Taiwan.; Department of Colorectal Cancer, China Medical University Hospital, Taichung, Taiwan.; Department of Colorectal Surgery, China Medical University HsinChu Hospital, China Medical University Hospital, HsinChu, Taiwan., Chao KSC; Proton Cancer, China Medical University Hospital, Taichung, Taiwan flylerd0425@gmail.com d94032@mail.cmuh.org.tw.; Department of Radiation Oncology, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, China Medical University, Taichung, Taiwan.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2024 May 15; Vol. 12 (5). Date of Electronic Publication: 2024 May 15.

Dual Inhibition of B7-H3 and EGFR Overcomes Acquired Chemoresistance in Colon Adenocarcinoma.

Autor: Chen LC; Department of Pathology, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan., Yang PC; Proton Therapy and Science Center, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan., Chen CY; Proton Therapy and Science Center, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan., Chiang SF; Lab of Precision Medicine, Feng-Yuan Hospital, Ministry of Health and Welfare, Taichung 42055, Taiwan., Chen TW; Department of Pathology, Asia University Hospital, Asia University, Taichung 41354, Taiwan., Chen WT; Department of Colorectal Surgery, China Medical University HsinChu Hospital, China Medical University, HsinChu 302, Taiwan.; Department of Colorectal Surgery, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan.; Department of Surgery, School of Medicine, China Medical University, Taichung 40402, Taiwan., Ke TW; Department of Colorectal Surgery, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan.; School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan., Liang JA; Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Department of Radiotherapy, School of Medicine, China Medical University, Taichung 40402, Taiwan., Shiau AC; Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung 40402, Taiwan., Chao KSC; Proton Therapy and Science Center, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan.; Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Department of Radiotherapy, School of Medicine, China Medical University, Taichung 40402, Taiwan., Huang KC; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung 40402, Taiwan.; Translation Research Core, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan.; Cancer Biology and Precision Therapeutics Center, China Medical University, Taichung 40402, Taiwan.

Publikováno v: Journal of Cancer [J Cancer] 2024 Feb 04; Vol. 15 (6), pp. 1750-1761. Date of Electronic Publication: 2024 Feb 04 (Print Publication: 2024).

TNFα modulates PANX1 activation to promote ATP release and enhance P2RX7-mediated antitumor immune responses after chemotherapy in colorectal cancer.

Autor: Huang KC; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, 40402, Taiwan, ROC. chihyang0425@mail.cmu.edu.tw.; Translation Research Core, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan, ROC. chihyang0425@mail.cmu.edu.tw.; Cancer Biology and Precision Therapeutics Center, China Medical University, Taichung, 40402, Taiwan, ROC. chihyang0425@mail.cmu.edu.tw., Chiang SF; Lab of Precision Medicine, Feng-Yuan Hospital, Ministry of Health and Welfare, Taichung, 42055, Taiwan, ROC., Lin PC; Proton Therapy and Science Center, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan, ROC., Hong WZ; Proton Therapy and Science Center, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan, ROC., Yang PC; Proton Therapy and Science Center, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan, ROC., Chang HP; Proton Therapy and Science Center, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan, ROC., Peng SL; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, 40402, Taiwan, ROC., Chen TW; Department of Pathology, Asia University Hospital, Asia University, Taichung, 41354, Taiwan, ROC., Ke TW; School of Chinese Medicine and Graduate Institute of Chinese Medicine, China Medical University, Taichung, 40402, Taiwan, ROC.; Department of Colorectal Surgery, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan, ROC., Liang JA; Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan, ROC.; Department of Radiotherapy, School of Medicine, China Medical University, Taichung, 40402, Taiwan, ROC., Chen WT; Department of Colorectal Surgery, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan, ROC.; Department of Colorectal Surgery, China Medical University HsinChu Hospital, China Medical University, HsinChu, 302, Taiwan, ROC.; School of Medicine, China Medical University, Taichung, 40402, Taiwan, ROC., Chao KSC; Proton Therapy and Science Center, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan, ROC. d94032@mail.cmuh.org.tw.; Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan, ROC. d94032@mail.cmuh.org.tw.; Department of Radiotherapy, School of Medicine, China Medical University, Taichung, 40402, Taiwan, ROC. d94032@mail.cmuh.org.tw.

Publikováno v: Cell death & disease [Cell Death Dis] 2024 Jan 09; Vol. 15 (1), pp. 24. Date of Electronic Publication: 2024 Jan 09.