Zobrazeno 1 - 10
of 6 086
pro vyhledávání: '"Ks, Lee"'
Autor:
Gerard Pernes, Pooranee K Morgan, Kevin Huynh, Corey Giles, Sudip Paul, Adam Alexander T Smith, Natalie A Mellett, Camilla Bertuzzo Veiga, Thomas JC Collins, T Michael De Silva, Man KS Lee, Peter J Meikle, Graeme I Lancaster, Andrew J Murphy
The cellular lipidome is comprised of thousands of unique lipid species. This complexity underpins the many roles of lipids in cellular biology. How lipidome composition varies between cell types and how such differences contribute to cell-specific f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655ad93c6f4343317ce82a95c9c91bfb
https://doi.org/10.1101/2023.02.10.528075
https://doi.org/10.1101/2023.02.10.528075
Autor:
KS Lee, Su Hyung Park
Publikováno v:
Experimental & Molecular Medicine
Eukaryotic sliding clamp proliferating cell nuclear antigen (PCNA) plays a critical role as a processivity factor for DNA polymerases and as a binding and acting platform for many proteins. The ring-shaped PCNA homotrimer and the DNA damage checkpoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5e3a13a212732c716bd3756127fb93
http://europepmc.org/articles/PMC8080817
http://europepmc.org/articles/PMC8080817
Autor:
KS Lee, Shinseog Kim, Su Hyung Park, Minwoo Wie, Jun Hong Park, Seong-Jung Kim, Tae Moon Kim, Kyungjae Myung
Publikováno v:
Cell Cycle
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Centrosomes are the primary microtubule-organizing centers that are important for mitotic spindle assembly. Centrosome amplification is commonly observed in human cancer cells and contributes to genomic instability. However, it is not clear how centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340dba2d4c97d6aaf31b72507a4a77c8
https://doi.org/10.1080/15384101.2020.1785724
https://doi.org/10.1080/15384101.2020.1785724
Autor:
Jae Sun Ra, Min Woo Wie, Kyungjae Myung, Youyoung Kim, Mi-Sun Kang, Sukhyun Kang, KS Lee, Su Hyung Park
Publikováno v:
Nucleic Acids Research
Reactive oxygen species (ROS) generate oxidized bases and single-strand breaks (SSBs), which are fixed by base excision repair (BER) and SSB repair (SSBR), respectively. Although excision and repair of damaged bases have been extensively studied, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bcb7ed24abf600cc0e26922d1a903f
https://pubmed.ncbi.nlm.nih.gov/34718749
https://pubmed.ncbi.nlm.nih.gov/34718749
Publikováno v:
Age and Ageing. 48:iv34-iv39
Background Falls is a major public health concern. In the older population, it is a risk factor for disability, frailty and further disability. However, most data is focused in Nursing Home residence and non-Asian population. Furthermore, despite Ort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c5baee1dff80c7b95bc84406cd29893
https://doi.org/10.1093/ageing/afz164.146
https://doi.org/10.1093/ageing/afz164.146
Autor:
Su Hyung Park, Sungchul Hohng, Minwoo Wie, Sukhyun Kang, KS Lee, Deokjae Lee, Jun Hong Park, Jae Sun Ra, In Bae Park, Sunyoung Hwang, Eun-Ho Song, Kyungjae Myung, Jieun Park, Eun A. Lee, Nalae Kang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
Maintaining stability of replication forks is important for genomic integrity. However, it is not clear how replisome proteins contribute to fork stability under replication stress. Here, we report that ATAD5, a PCNA unloader, plays multiple function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d195193d86b9525d6ad23ad3d26d42d6
https://doaj.org/article/4ac4913c149c4dd78292e37f24a832b8
https://doaj.org/article/4ac4913c149c4dd78292e37f24a832b8
Autor:
T.S. Kim, L. Fan, Yi Chen, Rodolfo Ghirlando, KS Lee, J. Il Ahn, Eunjung Lee, J.M. Lim, Yun Xing Wang, Jeannie Park, Bo Yeon Kim, Lisa Zhang, L. Meng, J.K. Bang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
The cell is constructed by higher-order structures and organelles through complex interactions among distinct structural constituents. The centrosome is a membraneless organelle composed of two microtubule-derived structures called centrioles and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573aade61ade455dfa369d205bea72b3
http://link.springer.com/article/10.1038/s41467-019-08838-2
http://link.springer.com/article/10.1038/s41467-019-08838-2
Autor:
Jungsil Ro, J-H Ahn, KS Lee, S-B Kim, K-H Lee, In Hae Park, KH Park, Y.S. Chae, Young-Ae Park, Sung Hoon Sim, S Lee, Jung Ho Sohn, KH Jung, Y-H Im, Hj. Kim, B-H Nam, S-A Im, Y. Kim
Publikováno v:
Cancer Research. 79:P6-17
Background The continuum of anti-HER2 agents is regarded as a standard strategy for HER2 positive metastatic breast cancer patients who had progressed disease with anti-HER2 agent- containing treatments. However, there has been lack of data on which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf4aabac4316b9f75d1bd7ab4af85c5c
https://doi.org/10.1158/1538-7445.sabcs18-p6-17-23
https://doi.org/10.1158/1538-7445.sabcs18-p6-17-23
Autor:
R-M Espadero, Joop P. W. van den Bergh, Jose Alejandro Perez-Fidalgo, A. Gonçalves, Serafin Morales, Peter Schmid, D Adamson, KS Lee, Aleix Prat, Patrick Neven, Noelia Martínez, G. Jerusalem, Y-S Lu, S-A Im, J. Cortés, J.P. Crown, L Schlieker, Thomas Bogenrieder, D Chin-Lun Huang, M.P. Sablin
Publikováno v:
Cancer Research. 79:P6-21
Background: Xentuzumab (Xen), an IGF-1/-2-neutralizing Ab, binds IGF-1 and IGF-2, inhibits their growth-promoting signaling, and suppresses AKT activation by everolimus (Ev). This Phase 1b/2 trial evaluates Xen in combination with Ev and exemestane (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e8374df546edd4ff7db37d80ba9c6a9
https://doi.org/10.1158/1538-7445.sabcs18-p6-21-01
https://doi.org/10.1158/1538-7445.sabcs18-p6-21-01
Autor:
T-Y Kim, K.H. Lee, J-H Ahn, J.H. Kim, KH Park, S-A Im, Young-Ae Park, KH Jung, IH Park, S-B Kim, Hye-Suk Han, K-H Lee, SH Sohn, KS Lee, Songhui Kim, Y.S. Chae, Eui Jin Lee, Y-H Im, J-Y Kim, S.J. Lee, Gun Min Kim
Publikováno v:
Cancer Research. 79:P3-11
Introduction : A phase II, multicenter, randomized clinical trial of the comparison between eribulin plus gemcitabine (EG) and paclitaxel plus gemcitabine (PG) as first-line chemotherapy for patients with human epidermal growth factor receptor 2 (HER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9377cc23cea3f3b6f01cabde683c570
https://doi.org/10.1158/1538-7445.sabcs18-p3-11-07
https://doi.org/10.1158/1538-7445.sabcs18-p3-11-07