Variation in the gene encoding the co-inhibitory molecule BTLA is associated with survival in patients treated for clear cell renal carcinoma – results of a prospective cohort study

Autor: Krzysztof Tupikowski, Anna Partyka, Edyta A. Pawlak, Kuba Ptaszkowski, Romuald Zdrojowy, Irena Frydecka, Agnieszka Hałoń, Lidia Karabon

Publikováno v: Archives of Medical Science, Vol 19, Iss 5, Pp 1454-1462 (2021)

Introduction The successful introduction of immune checkpoint blockade approaches to renal-cell carcinoma (RCC) treatment indicates the importance of molecules regulating the T cell response to RCC risk and progression. Material and methods In this

Externí odkaz: https://doaj.org/article/0ae19a685cb54a849bf9549e8f411d69

Patient comfort during flexible and rigid cystourethroscopy

Autor: Wojciech Krajewski, Romuald Zdrojowy, Joanna Wojciechowska, Katarzyna Kościelska, Janusz Dembowski, Michał Matuszewski, Krzysztof Tupikowski, Bartosz Małkiewicz, Anna Kołodziej

Publikováno v: Videosurgery and Other Miniinvasive Techniques, Vol 11, Iss 2, Pp 94-97 (2016)

Introduction : Cystourethroscopy (CS) is an endoscopic method used to visualize the urethra and the bladder. Aim: In this study , we prospectively evaluated pain in men undergoing cyclic cystoscopic assessment with rigid and flexible instruments afte

Externí odkaz: https://doaj.org/article/d516f8e3f1264bc78d5b06ca338c5939

Treatment of muscle-invasive urothelial cancer with nivolumab (CheckMate 274 study): a plain language summary

Autor: Dean F Bajorin, J Alfred Witjes, Jürgen E Gschwend, Michael Schenker, Begoña P Valderrama, Yoshihiko Tomita, Aristotelis Bamias, Thierry Lebret, Shahrokh F. Shariat, Se Hoon Park, Dingwei Ye, Mads Agerbaek, Deborah Enting, Ray McDermott, Pablo Gajate, Avivit Peer, Matthew I Milowsky, Alexander Nosov, João Neif Antonio, Krzysztof Tupikowski, Laurence Toms, Bruce S Fischer, Anila Qureshi, Sandra Collette, Keziban Unsal-Kacmaz, Edward Broughton, Dimitrios Zardavas, Henry B Koon, Matthew D Galsky

Publikováno v: Future Oncology, 19, 6, pp. 413-426

What is this summary about? This is a summary of a paper published in a medical journal that describes the results of a study called CheckMate 274. This study looked at a new treatment for muscle-invasive urothelial cancer, a type of cancer found in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89349f1ec33b073c93793429d35634a8

Adjuvant Nivolumab versus Placebo in Muscle-Invasive Urothelial Carcinoma

Autor: Shahrokh F. Shariat, Alexander Nosov, Aristotelis Bamias, T. Lebret, Matthew I. Milowsky, Yoshihiko Tomita, Matthew D. Galsky, Dingwei Ye, Begoña P. Valderrama, Deborah Enting, Edward Broughton, Mads Agerbaek, João Neif Antonio, Michael Schenker, Dimitrios Zardavas, Pablo Gajate, Se Hoon Park, Henry B. Koon, Ray McDermott, Krzysztof Tupikowski, Avivit Peer, Bruce S. Fischer, Dean F Bajorin, Keziban Unsal-Kacmaz, J. Alfred Witjes, Laurence Toms, Sandra Collette, Anila Qureshi, Jürgen E. Gschwend

Publikováno v: The New England Journal of Medicine, 384, 22, pp. 2102-2114
New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2021, 384 (22), pp.2102-2114. ⟨10.1056/NEJMoa2034442⟩
N Engl J Med
Bajorin, D F, Witjes, J A, Gschwend, J E, Schenker, M, Valderrama, B P, Tomita, Y, Bamias, A, Lebret, T, Shariat, S F, Park, S H, Ye, D, Agerbaek, M, Enting, D, McDermott, R, Gajate, P, Peer, A, Milowsky, M I, Nosov, A, Antonio, J N, Tupikowski, K, Toms, L, Fischer, B S, Qureshi, A, Collette, S, Unsal-Kacmaz, K, Broughton, E, Zardavas, D, Koon, H B & Galsky, M D 2021, ' Adjuvant Nivolumab versus Placebo in Muscle-Invasive Urothelial Carcinoma ', New England Journal of Medicine, vol. 384, no. 22, pp. 2102-2114 . https://doi.org/10.1056/NEJMoa2034442
The New England Journal of Medicine, 384, 2102-2114

BACKGROUND: The role of adjuvant treatment in high-risk muscle-invasive urothelial carcinoma after radical surgery is not clear. METHODS: In a phase 3, multicenter, double-blind, randomized, controlled trial, we assigned patients with muscle-invasive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606457002294dbe1ff3243ad786b01e3
https://hdl.handle.net/2066/234161

The Variations’ in Genes Encoding TIM-3 and Its Ligand, Galectin-9, Influence on ccRCC Risk and Prognosis

Autor: Anna Andrzejczak, Krzysztof Tupikowski, Anna Tomkiewicz, Bartosz Małkiewicz, Kuba Ptaszkowski, Aleksandra Domin, Tomasz Szydełko, Lidia Karabon

Publikováno v: International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2042

Renal cell cancer is the most common type of kidney cancer in adults, and clear cell renal cell carcinoma (ccRCC) is the most diagnosed type. T cell immunoglobulin and mucin-domain-containing-3 (TIM-3) belongs to immunological checkpoints that are ke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed0cfbc7e048d5b09e3a0ce5e926951
https://doi.org/10.3390/ijms24032042