Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Krzysztof Pawłowski"'
Autor:
Leticia Szadai, Aron Bartha, Indira Pla Parada, Alexandra I.T. Lakatos, Dorottya M.P. Pál, Anna Sára Lengyel, Natália Pinto de Almeida, Ágnes Judit Jánosi, Fábio Nogueira, Beata Szeitz, Viktória Doma, Nicole Woldmar, Jéssica Guedes, Zsuzsanna Ujfaludi, Zoltán Gábor Pahi, Tibor Pankotai, Yonghyo Kim, Balázs Győrffy, Bo Baldetorp, Charlotte Welinder, A. Marcell Szasz, Lazaro Betancourt, Jeovanis Gil, Roger Appelqvist, Ho Jeong Kwon, Sarolta Kárpáti, Magdalena Kuras, Jimmy Rodriguez Murillo, István Balázs Németh, Johan Malm, David Fenyö, Krzysztof Pawłowski, Peter Horvatovich, Elisabet Wieslander, Lajos V. Kemény, Gilberto Domont, György Marko-Varga, Aniel Sanchez
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionWhile Immune checkpoint inhibition (ICI) therapy shows significant efficacy in metastatic melanoma, only about 50% respond, lacking reliable predictive methods. We introduce a panel of six proteins aimed at predicting response to ICI ther
Externí odkaz:
https://doaj.org/article/fe95ef6a509c4265b300a1ff4e58f88f
Autor:
Jacek Klaudel, Piotr Radowski, Wojciech Trenkner, Michał Glaza, Krzysztof Pawłowski, Dariusz Surman, Włodzimierz Krasowski, Marek Szołkiewicz
Publikováno v:
Journal of Vascular Diseases, Vol 2, Iss 4, Pp 402-412 (2023)
Background: Coronary aneurysms are an infrequent finding in diagnostic angiography, with a reported incidence of 0.35–0.7% in the largest contemporary registries. At least half of them have an atherosclerotic etiology and as such they are often dia
Externí odkaz:
https://doaj.org/article/023d4a7018e2452daec36eae7d89aaf9
Autor:
Hayarpi Torosyan, Michael D. Paul, Antoine Forget, Megan Lo, Devan Diwanji, Krzysztof Pawłowski, Nevan J. Krogan, Natalia Jura, Kliment A. Verba
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract PEAK pseudokinases are molecular scaffolds which dimerize to regulate cell migration, morphology, and proliferation, as well as cancer progression. The mechanistic role dimerization plays in PEAK scaffolding remains unclear, as there are no
Externí odkaz:
https://doaj.org/article/85045834d2964cfea366be106c88604c
Autor:
Shashank Shekhar, Andrew T. Moehlman, Brenden Park, Michael Ewnetu, Charles Tracy, Iris Titos, Krzysztof Pawłowski, Vincent S. Tagliabracci, Helmut Krämer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract In nervous systems, retrograde signals are key for organizing circuit activity and maintaining neuronal homeostasis. We identify the conserved Allnighter (Aln) pseudokinase as a cell non-autonomous regulator of proteostasis responses necessa
Externí odkaz:
https://doaj.org/article/7b95dc1421884eb6be290afdee3302f1
Autor:
Marianna Krysińska, Bartosz Baranowski, Bartłomiej Deszcz, Krzysztof Pawłowski, Marcin Gradowski
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The pathogenic Legionella bacteria are notorious for delivering numerous effector proteins into the host cell with the aim of disturbing and hijacking cellular processes for their benefit. Despite intensive studies, many effectors remain unc
Externí odkaz:
https://doaj.org/article/80c4cbd7dfc94fb18f9f6b12d949008f
Publikováno v:
PeerJ, Vol 11, p e15715 (2023)
Background Functionally related genes are well known to be often grouped in close vicinity in the genomes, particularly in prokaryotes. Notwithstanding the diverse evolutionary mechanisms leading to this phenomenon, it can be used to predict function
Externí odkaz:
https://doaj.org/article/f7e02d2f39e2483087cd176d6c3a6e03
Publikováno v:
Advances in Interventional Cardiology, Vol 18, Iss 1, Pp 4-13 (2022)
The interventional treatment of acute ischemic stroke with large vessel occlusion has revolutionized patient care in recent years. The Mechanical Thrombectomy Pilot Program in Poland is due to end soon. It seems the right time to summarize the achiev
Externí odkaz:
https://doaj.org/article/fd24c7955ef2458ea3fa5fe98b577953
Publikováno v:
Advances in Interventional Cardiology, Vol 18, Iss 1, Pp 65-69 (2022)
Despite inconclusive and conflicting results of trials and meta-analyses assessing aspiration thrombectomy in ST-segment elevation myocardial infarction (STEMI), trends toward reduced mortality were observed in the high thrombus burden subgroup [1–
Externí odkaz:
https://doaj.org/article/29d25d688d954b50ac74acab255caefb
Autor:
Krzysztof Pawłowski
Publikováno v:
Budownictwo o Zoptymalizowanym Potencjale Energetycznym, Vol 10, Iss 2, Pp 23-30 (2021)
The article introduces selected aspects of creating material sets for an external wall connection with a balcony slab. The integral part of this work are calculations and analyses concerning the thermal quality of joints with balcony slabs produced
Externí odkaz:
https://doaj.org/article/708ba4f040ad49daa166d86bf239f0fa
Publikováno v:
Physical Review Research, Vol 5, Iss 2, p 023050 (2023)
We propose and benchmark a Gross-Pitaevskii-like equation for two-component Bose mixtures with competing interactions in 1D. Our approach follows the density functional theory with the energy functional based on the exact quantum Monte Carlo (QMC) si
Externí odkaz:
https://doaj.org/article/c51e86663f1447708b871776bfaefba4