Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Krzysztof M. Mrozik"'
Autor:
Natasha L. Friend, Duncan R. Hewett, Vasilios Panagopoulos, Jacqueline E. Noll, Kate Vandyke, Krzysztof M. Mrozik, Stephen Fitter, Andrew C.W. Zannettino
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 9, Pp 554-572 (2020)
Abstract The protein SAMSN1 was recently identified as a putative tumor suppressor in multiple myeloma, with re‐expression of Samsn1 in the 5TGM1/KaLwRij murine model of myeloma leading to a near complete abrogation of intramedullary tumor growth.
Externí odkaz:
https://doaj.org/article/156a98f254f24fe5bd74506dfb885296
Autor:
Krzysztof M. Mrozik, Chee M. Cheong, Duncan R. Hewett, Jacqueline E. Noll, Khatora S. Opperman, Alaknanda Adwal, Darryl L. Russell, Orest W. Blaschuk, Kate Vandyke, Andrew C. W. Zannettino
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 6, Pp 339-353 (2020)
Abstract N‐cadherin is a homophilic cell‐cell adhesion molecule that plays a critical role in maintaining vascular stability and modulating endothelial barrier permeability. Pre‐clinical studies have shown that the N‐cadherin antagonist pepti
Externí odkaz:
https://doaj.org/article/c6826197d1b54a479b78471d9ab82b5d
Autor:
Mara N. Zeissig, Duncan R. Hewett, Vasilios Panagopoulos, Krzysztof M. Mrozik, L. Bik To, Peter I. Croucher, Andrew C.W. Zannettino, Kate Vandyke
Publikováno v:
Haematologica, Vol 106, Iss 12 (2020)
Multiple myeloma (MM) disease progression is dependent on the ability of MM plasma cells (PC) to egress from the bone marrow (BM), enter the circulation and disseminate to distal BM sites. Expression of the chemokine CXCL12 by BM stromal cells is cru
Externí odkaz:
https://doaj.org/article/6d1b9b271dcc4ee990634f98c7077a89
Autor:
Kimberley C. Clark, Duncan R. Hewett, Vasilios Panagopoulos, Natalya Plakhova, Khatora S. Opperman, Alanah L. Bradey, Krzysztof M. Mrozik, Kate Vandyke, Siddhartha Mukherjee, Gareth C.G. Davies, Daniel L. Worthley, Andrew C.W. Zannettino
Publikováno v:
Cancers, Vol 12, Iss 8, p 2149 (2020)
In most instances, multiple myeloma (MM) plasma cells (PCs) are reliant on factors made by cells of the bone marrow (BM) stroma for their survival and growth. To date, the nature and cellular composition of the BM tumor microenvironment and the criti
Externí odkaz:
https://doaj.org/article/b4bf9c46db4b4baabdc516cddbd4332c
Autor:
Andrew C.W. Zannettino, Peter I. Croucher, Daniel J. Peet, Stan Gronthos, L. Bik To, Peter Diamond, Chee Man Cheong, Krzysztof M. Mrozik, Sally K. Martin, Duncan R. Hewett, Mara N. Zeissig, Kate Vandyke
Disease progression and relapse in multiple myeloma is dependent on the ability of the multiple myeloma plasma cells (PC) to reenter the circulation and disseminate throughout the bone marrow. Increased bone marrow hypoxia is associated with increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7becda77a17ee4d0f7f53c99a9f7db93
https://doi.org/10.1158/0008-5472.c.6509067.v1
https://doi.org/10.1158/0008-5472.c.6509067.v1
Autor:
Andrew C.W. Zannettino, Peter I. Croucher, Daniel J. Peet, Stan Gronthos, L. Bik To, Peter Diamond, Chee Man Cheong, Krzysztof M. Mrozik, Sally K. Martin, Duncan R. Hewett, Mara N. Zeissig, Kate Vandyke
Table of genes dysregulated with overexpression of HIF-2alpha in LP-1 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1748287a0abc55f9f56d92b93286e3c9
https://doi.org/10.1158/0008-5472.22414728.v1
https://doi.org/10.1158/0008-5472.22414728.v1
Autor:
Andrew C.W. Zannettino, Peter I. Croucher, Daniel J. Peet, Stan Gronthos, L. Bik To, Peter Diamond, Chee Man Cheong, Krzysztof M. Mrozik, Sally K. Martin, Duncan R. Hewett, Mara N. Zeissig, Kate Vandyke
Supplementary Figure Legends and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e9da169194aece84a84b17d52ede9d
https://doi.org/10.1158/0008-5472.22414731.v1
https://doi.org/10.1158/0008-5472.22414731.v1
Autor:
Andrew C.W. Zannettino, Peter I. Croucher, Daniel J. Peet, Stan Gronthos, L. Bik To, Peter Diamond, Chee Man Cheong, Krzysztof M. Mrozik, Sally K. Martin, Duncan R. Hewett, Mara N. Zeissig, Kate Vandyke
Supp. Figure 3. CCR1 expression is upregulated by hypoxia in human MM cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab4117931f9b2b3437db2c911888946
https://doi.org/10.1158/0008-5472.22414740
https://doi.org/10.1158/0008-5472.22414740
Autor:
Andrew C.W. Zannettino, Peter I. Croucher, Daniel J. Peet, Stan Gronthos, L. Bik To, Peter Diamond, Chee Man Cheong, Krzysztof M. Mrozik, Sally K. Martin, Duncan R. Hewett, Mara N. Zeissig, Kate Vandyke
GSEA for genes upregulated by overexpression of HIF-2alpha in LP-1 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb8b8e384868021dde3cdd3917cecac
https://doi.org/10.1158/0008-5472.22414725
https://doi.org/10.1158/0008-5472.22414725
Autor:
Andrew C.W. Zannettino, Peter I. Croucher, Daniel J. Peet, Stan Gronthos, L. Bik To, Peter Diamond, Chee Man Cheong, Krzysztof M. Mrozik, Sally K. Martin, Duncan R. Hewett, Mara N. Zeissig, Kate Vandyke
Supp. Figure 5. Cell surface expression of CXCR4 and CCR1 in newly diagnosed MM patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c402eb5d5caf29a46c1f29387b922f
https://doi.org/10.1158/0008-5472.22414734
https://doi.org/10.1158/0008-5472.22414734