Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Krzysztof Ginalski"'
Autor:
Michalina Wężyk, Mariusz Berdyński, Adam Figarski, Magdalena Skrzypczak, Krzysztof Ginalski, Marzena Zboch, Izabela Winkel, Cezary Żekanowski
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16999 (2023)
Presenilin 1 (PS1) forms, via its large cytosolic loop, a trimeric complex with N-cadherin and β-catenin, which is a key component of Wnt signaling. PS1 undergoes phosphorylation at 353 and 357 serines upon enhanced activity and elevated levels of t
Externí odkaz:
https://doaj.org/article/3fe44ada59de48ddbcb563865499d60a
Autor:
Alexy Promonet, Ismaël Padioleau, Yaqun Liu, Lionel Sanz, Anna Biernacka, Anne-Lyne Schmitz, Magdalena Skrzypczak, Amélie Sarrazin, Clément Mettling, Maga Rowicka, Krzysztof Ginalski, Frédéric Chedin, Chun-Long Chen, Yea-Lih Lin, Philippe Pasero
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
While R-loops can alter cell homeostasis, it is unclear what determines their toxicity. Here, the authors, by using Top1 knockdown as a tool to enhance the formation of R-loops at certain genomic sites, reveal and characterize a proportion of R-loops
Externí odkaz:
https://doaj.org/article/bd1932962b864455ac3b032015f1a0ac
Autor:
Yingjie Zhu, Anna Biernacka, Benjamin Pardo, Norbert Dojer, Romain Forey, Magdalena Skrzypczak, Bernard Fongang, Jules Nde, Razie Yousefi, Philippe Pasero, Krzysztof Ginalski, Maga Rowicka
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Measuring relative frequencies of DNA double-strand breaks between loci does not provide the full physiological relevance of those breaks. Here Rowicka and colleagues present qDSB-Seq method which uses spike-in double-strand breaks induced by a restr
Externí odkaz:
https://doaj.org/article/1da150c75932433b96bb662db60a6ecc
Autor:
Dorota Matelska, Ivan G. Shabalin, Jagoda Jabłońska, Marcin J. Domagalski, Jan Kutner, Krzysztof Ginalski, Wladek Minor
Publikováno v:
BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-23 (2018)
Abstract Background The family of D-isomer specific 2-hydroxyacid dehydrogenases (2HADHs) contains a wide range of oxidoreductases with various metabolic roles as well as biotechnological applications. Despite a vast amount of biochemical and structu
Externí odkaz:
https://doaj.org/article/6aad9b04fefb49438edca403f440735c
Autor:
Krzysztof Goryca, Maria Kulecka, Agnieszka Paziewska, Michalina Dabrowska, Marta Grzelak, Magdalena Skrzypczak, Krzysztof Ginalski, Andrzej Mroz, Andrzej Rutkowski, Katarzyna Paczkowska, Michal Mikula, Jerzy Ostrowski
Publikováno v:
BMC Genetics, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background Approximately 90% of colorectal cancer (CRC) deaths are caused by tumors ability to migrate into the adjacent tissues and metastase into distant organs. More than 40 genes have been causally linked to the development of CRC but no
Externí odkaz:
https://doaj.org/article/40ddefb9e33f4e40a557348eb4dc65b9
Autor:
Xavier Argemi, Dorota Matelska, Krzysztof Ginalski, Philippe Riegel, Yves Hansmann, Jochen Bloom, Martine Pestel-Caron, Sandrine Dahyot, Jérémie Lebeurre, Gilles Prévost
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-16 (2018)
Abstract Background Coagulase negative staphylococci (CoNS) are commensal bacteria on human skin. Staphylococcus lugdunensis is a unique CoNS which produces various virulence factors and may, like S. aureus, cause severe infections, particularly in h
Externí odkaz:
https://doaj.org/article/d8665cf6b47b4bea8ff5e45169d184d5
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Double-strand breaks (DSBs) result from the attack of both DNA strands by multiple sources, including radiation and chemicals. DSBs can cause the abnormal chromosomal rearrangements associated with cancer. Recent techniques allow the genome-
Externí odkaz:
https://doaj.org/article/b891b4d1e9d6447f9800a4e522a0dfcd
Autor:
Anna Muszewska, Marta M. Stepniewska-Dziubinska, Kamil Steczkiewicz, Julia Pawlowska, Agata Dziedzic, Krzysztof Ginalski
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Fungi are able to switch between different lifestyles in order to adapt to environmental changes. Their ecological strategy is connected to their secretome as fungi obtain nutrients by secreting hydrolytic enzymes to their surrounding and ac
Externí odkaz:
https://doaj.org/article/498056da17074b239799fc19bf436e0c
Autor:
Dorota Matelska, Ivan G. Shabalin, Jagoda Jabłońska, Marcin J. Domagalski, Jan Kutner, Krzysztof Ginalski, Wladek Minor
Publikováno v:
BMC Psychiatry, Vol 19, Iss 1, Pp 1-1 (2019)
Following publication of the original article [1], we have been notified that some important information was omitted by the authors from the Competing interests section. The declaration should read as below.
Externí odkaz:
https://doaj.org/article/029f317c4eac4017b7b8dd676c10fa94
Autor:
Elżbieta Gryz, Urszula Perlińska-Lenart, Katarzyna Gawarecka, Adam Jozwiak, Sebastian Piłsyk, Agata Lipko, Malgorzata Jemiola-Rzeminska, Przemysław Bernat, Anna Muszewska, Kamil Steczkiewicz, Krzysztof Ginalski, Jerzy Długoński, Kazimierz Strzalka, Ewa Swiezewska, Joanna S. Kruszewska
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3043 (2019)
Mono-saturated polyprenols (dolichols) have been found in almost all Eukaryotic cells, however, dolichols containing additional saturated bonds at the ω-end, have been identified in A. fumigatus and A. niger. Here we confirm using an LC-ESI-QTOF-MS
Externí odkaz:
https://doaj.org/article/3fa79cdd680242dda68d5b7e0c8a2ff5