Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Krzysztof, Zwoliński"'
Publikováno v:
Tutoring Gedanensis. 7:14-24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22318f265a34c6c98dc665d18a50d37b
https://doi.org/10.26881/tutg.2022.3.02
https://doi.org/10.26881/tutg.2022.3.02
Autor:
Krzysztof Zwoliński, Julita Eilmes
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 617-622 (2019)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
The first crown ether-capped dibenzotetraaza[14]annulenes (DBTAAs), featuring two macrocyclic binding sites fixed in a face-to-face orientation, were synthesized in satisfactory 26–28% isolated yields. Direct N-alkylation of 1,4,10-trioxa-7,13-diaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a396c3608ea212dbc73b2b61a04cb9e
https://doi.org/10.3762/bjoc.15.57
https://doi.org/10.3762/bjoc.15.57
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-14 (2018)
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases
Background A Multi Criteria Decision Analysis (MCDA) technique was adopted to reveal the preferences of the Appraisal Body of the Polish HTA agency towards orphan drugs (OMPs). Results There were 34 positive and 23 negative HTA recommendations out of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2023888a1a73bacccf174b40095ff5
http://link.springer.com/article/10.1186/s13023-018-0803-9
http://link.springer.com/article/10.1186/s13023-018-0803-9
Autor:
Krzysztof Zwoliński, Julita Eilmes
Publikováno v:
Organic & Biomolecular Chemistry. 16:5508-5516
The first series of discrete multichromophore arrays of dibenzotetraaza[14]annulene (DBTAA), containing flexible bridges, have been synthesized in 40-46% isolated yields. The key asymmetrical intermediates, carrying two distinctly addressable functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981e0626aa6ffe157fbf28564fe56fbd
https://doi.org/10.1039/c8ob01078a
https://doi.org/10.1039/c8ob01078a
Publikováno v:
Organic Chemistry Frontiers. 5:171-178
A macrocyclic precursor featuring highly reactive propargylic moieties was prepared via Williamson etherification in good yields of 54–65%. Organometallic methodology paired with protective metal insertion served as the foundation for better DBTAA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7811f96d018a353e5ec383c7d5a8bb
https://doi.org/10.1039/c7qo00821j
https://doi.org/10.1039/c7qo00821j
Autor:
Michał Matuszewski, Agnieszka B. Olejniczak, Aneta Dąbrowska, Krzysztof Zwoliński, Anna Ignaczak
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 111
Lipophilicity was investigated for 20 2'-deoxyribonucleoside derivatives modified with electron-neutral 1,2-dicarba-closo-dodecaborane, 1,12-dicarba-closo-dodecaborane, 7,8-dicarba-nido-undecaborate anion, and metallacarborane containing Co, Fe, or C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2613474b35db36d463e5cc3d351d6fc8
https://pubmed.ncbi.nlm.nih.gov/28986193
https://pubmed.ncbi.nlm.nih.gov/28986193
Publikováno v:
Orphanet Journal of Rare Diseases
Background The objective of this study was to assess the potential impact of the implementation of multiple-criteria decision analysis (MCDA) on the Polish pricing and reimbursement (P&R) process with regard to orphan drugs. Methods A four step appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516b7b3e99c775fef8a5c6b76bf75a2b
http://europepmc.org/articles/PMC4787054
http://europepmc.org/articles/PMC4787054
Autor:
Krzysztof Zwoliński, Julita Eilmes
The first known homoleptic cofacial dimers, based on covalently linked dibenzotetraaza[14]annulenes, were synthesized in reasonable 35-40% yields, without recourse to high-dilution techniques. Dinuclear zinc(ii) dimer showed strong binding affinity t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf53262f57347b060eeb8b6a4bc64286
https://ruj.uj.edu.pl/xmlui/handle/item/52643
https://ruj.uj.edu.pl/xmlui/handle/item/52643
Autor:
Anna, Adamska, Agnieszka B, Olejniczak, Krzysztof, Zwoliński, Wojciech J, Szczepek, Ewelina, Król, Bogusław, Szewczyk, Grzegorz, Grynkiewicz, Zbigniew J, Leśnikowski
Publikováno v:
Acta poloniae pharmaceutica. 69(6)
Synthesis of novel neuraminidase inhibitor -- carborane ester of oseltamivir carboxylic acid is described, and its physicochemical and spectral characteristics is provided. Surprisingly, carborane analog of oseltamivir is of an order of magnitude les
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::654deffa9c7634009559322d81346a56
https://pubmed.ncbi.nlm.nih.gov/23285684
https://pubmed.ncbi.nlm.nih.gov/23285684
The bis(2-hydroxybenzoyl) derivative of dibenzotetraaza[14]annulene was employed as a substrate for producing new lacunar-type receptors. Alkylation of both phenolic OH groups using aliphatic dibromides and ditosylates efficiently leads to the expect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242a185a182a5a3dbffe7a7de4796c8a
https://ruj.uj.edu.pl/xmlui/handle/item/69410
https://ruj.uj.edu.pl/xmlui/handle/item/69410