Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Krzysztof, Sładek"'
Autor:
Agnieszka Gawlewicz-Mroczka, Marek Przybyszowski, Grażyna Bochenek, Maria Mroczka, Krzysztof Sładek
Publikováno v:
Respiratory Medicine Case Reports, Vol 52, Iss , Pp 102136- (2024)
Dupilumab is a monoclonal antibody that has recently been introduced for the treatment of asthma. It has the potential to significantly alter the progression and severity of T2 -dependent diseases, including severe asthma. However, dupilumab can caus
Externí odkaz:
https://doaj.org/article/4d2f34a5bf454071a25e07c60d218007
Autor:
Agnieszka Olszanecka, Wiktoria Wojciechowska, Agnieszka Bednarek, Piotr Kusak, Barbara Wizner, Michał Terlecki, Katarzyna Stolarz-Skrzypek, Marek Klocek, Tomasz Drożdż, Krzysztof Sładek, Monika Bociąga-Jasik, Aleksander Garlicki, Krzysztof Rewiuk, Andrzej Matyja, Maciej Małecki, Wojciech Sydor, Marcin Krzanowski, Tomasz Grodzicki, Marek Rajzer
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundIt is a well-known fact that COVID-19 affects the cardiovascular system by exacerbating heart failure in patients with preexisting conditions. However, there is a poor insight into the cardiovascular involvement and sequelae in patients wit
Externí odkaz:
https://doaj.org/article/fe5198507fe740bd83daa2c2d5dc3f31
Autor:
Katarzyna Górska, Marta Maskey-Warzęchowska, Małgorzata Barnaś, Adam Białas, Adam Barczyk, Hanna Jagielska-Len, Ewa Jassem, Aleksander Kania, Katarzyna Lewandowska, Sebastian Majewski, Magdalena M. Martusewicz-Boros, Wojciech J. Piotrowski, Alicja Siemińska, Krzysztof Sładek, Małgorzata Sobiecka, Marzena Trzaska-Sobczak, Witold Tomkowski, Beata Żołnowska, Rafał Krenke
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 13 (2022)
Background: Pirfenidone and nintedanib are considered as the standard of care in idiopathic pulmonary fibrosis (IPF), but there is no consensus as to which of these two agents should be regarded as first-line treatment. Objective: To provide real-wor
Externí odkaz:
https://doaj.org/article/f292078d43f34b2ea0136d89cf7f4dc6
Autor:
Milena Paw, Dawid Wnuk, Bogdan Jakieła, Grażyna Bochenek, Krzysztof Sładek, Zbigniew Madeja, Marta Michalik
Publikováno v:
BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background The asthma-related airway wall remodeling is associated i.a. with a damage of bronchial epithelium and subepithelial fibrosis. Functional interactions between human bronchial epithelial cells and human bronchial fibroblasts are kn
Externí odkaz:
https://doaj.org/article/3ba120c1d64f48538ea8958adce8ef8c
Autor:
Paweł Nastałek, Kamil Polok, Natalia Celejewska-Wójcik, Aleksander Kania, Krzysztof Sładek, Piotr Małczak, Piotr Major
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract To evaluate association between bariatric surgery and changes in obstructive sleep apnea (OSA) severity and sleep architecture was as well as to asses continuous positive airway pressure (CPAP) effectiveness and compliance. We enrolled patie
Externí odkaz:
https://doaj.org/article/e35fe50f6b4144b1b8f9e43233125a93
Autor:
Dawid Wnuk, Milena Paw, Karolina Ryczek, Grażyna Bochenek, Krzysztof Sładek, Zbigniew Madeja, Marta Michalik
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Airway remodelling with subepithelial fibrosis, which abolishes the physiological functions of the bronchial wall, is a major issue in bronchial asthma. Human bronchial fibroblasts (HBFs) derived from patients diagnosed with asthma display i
Externí odkaz:
https://doaj.org/article/4e8d04ff46cd4efcaa6314b15934e936
Autor:
Sebastian Majewski, Adam J. Białas, Małgorzata Buchczyk, Paweł Gomółka, Katarzyna Górska, Hanna Jagielska-Len, Agnieszka Jarzemska, Ewa Jassem, Dariusz Jastrzębski, Aleksander Kania, Marek Koprowski, Rafał Krenke, Jan Kuś, Katarzyna Lewandowska, Magdalena M. Martusewicz-Boros, Kazimierz Roszkowski-Śliż, Alicja Siemińska, Krzysztof Sładek, Małgorzata Sobiecka, Karolina Szewczyk, Małgorzata Tomczak, Witold Tomkowski, Elżbieta Wiatr, Dariusz Ziora, Beata Żołnowska, Wojciech J. Piotrowski
Publikováno v:
BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Pirfenidone is an antifibrotic agent approved for the treatment of idiopathic pulmonary fibrosis (IPF). The drug is available for Polish patients with IPF since 2017. The PolExPIR study aimed to describe the real-world data (RWD)
Externí odkaz:
https://doaj.org/article/819a0c653b2745e99c064475c66a7334
Autor:
Anet Kivihall, Alar Aab, Jerzy Soja, Krzysztof Sładek, Marek Sanak, Alan Altraja, Bogdan Jakiela, Grazyna Bochenek, Ana Rebane
Publikováno v:
Clinical and Translational Allergy, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract Background The role of miRNAs in the pathogenesis and determining the phenotypes of asthma is not fully elucidated. miR-146a has been previously shown to suppress inflammatory responses in different cells. In this study, we investigated the
Externí odkaz:
https://doaj.org/article/7ce597ff346b4234a90e6252ce5c383d
Autor:
Aleksander Kania, Paweł Nastałek, Natalia Celejewska-Wójcik, Krzysztof Sładek, Marcin Kosobudzki, Alicja Bortkiewicz, Jadwiga Siedlecka
Publikováno v:
International Journal of Occupational Medicine and Environmental Health, Vol 32, Iss 5, Pp 735-745 (2019)
Road accidents are among the main fatalities worldwide and drowsy driving is a significant cause of road deaths where drivers are at fault. There are well known diseases which impair sensory and cognitive functions and can cause sleepiness during dri
Externí odkaz:
https://doaj.org/article/3dd07166e3934b419605dfee77fa1b66
Autor:
Iwona Gilowska, Edyta Majorczyk, Łukasz Kasper, Katarzyna Bogacz, Jan Szczegielniak, Marta Kasper, Jacek Kaczmarski, Aleksandra Skomudek, Marcin Czerwinski, Krzysztof Sładek
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-7 (2019)
Abstract Background Major symptoms of chronic obstructive pulmonary disease (COPD) are chronic bronchitis and emphysema leading from lung tissue destruction, that is an effect of an imbalance between metalloproteinases (MMPs) and their tissue inhibit
Externí odkaz:
https://doaj.org/article/56f26f1dd2f4443f961c6d625bea1da8