Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Krystyna Michalak"'
Autor:
Paulina Paluchowska, Simeon Lim Rossmann, Erik Lysøe, Marta Janiszewska, Krystyna Michalak, Rasoul Heydarnajad Giglou, Mousa Torabi Giglou, May Bente Brurberg, Jadwiga Śliwka, Zhimin Yin
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Potato virus Y (PVY) is among the economically most damaging viral pathogen in production of potato (Solanum tuberosum) worldwide. The gene Ry sto derived from the wild potato relative Solanum stoloniferum confers extreme resistan
Externí odkaz:
https://doaj.org/article/3766324d2a394899a8416204924c0b57
Autor:
Jadwiga Maniewska, Justyna Gąsiorowska, Żaneta Czyżnikowska, Krystyna Michalak, Berenika M. Szczęśniak-Sięga
Publikováno v:
Membranes, Vol 13, Iss 4, p 416 (2023)
The purpose of the present paper was to assess the ability of five newly designed and synthesized meloxicam analogues to interact with phospholipid bilayers. Calorimetric and fluorescence spectroscopic measurements revealed that, depending on the det
Externí odkaz:
https://doaj.org/article/6bb28e01df17413bb941e599802de13b
Autor:
Anna Palko-Łabuz, Kamila Środa-Pomianek, Olga Wesołowska, Edyta Kostrzewa-Susłow, Anna Uryga, Krystyna Michalak
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 109, Iss , Pp 1511-1522 (2019)
The resistance of cancer cells to a variety of structurally non-related cytotoxic drugs is known as multidrug resistance phenomenon (MDR). In cellular membranes an activity of MDR transporters such as P-glycoprotein (ABCB1) is affected by their lipid
Externí odkaz:
https://doaj.org/article/89f6fd70c04f42ea9682fe3f40bbb270
Publikováno v:
Membranes, Vol 12, Iss 8, p 791 (2022)
The modified 1,2-benzothiazine analogues designed as new drug candidates and discussed in this paper are oxicam derivatives. Oxicams are a class of non-steroidal anti-inflammatory drugs (NSAIDs). Their biological target is cyclooxygenase (COX), a mem
Externí odkaz:
https://doaj.org/article/3d9361d521cc4b3eb6d3ff72edae5a39
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Voltage-gated potassium channel Kv1.3 is an integral membrane protein, which is selectively permeable for potassium ions and is activated upon a change of membrane potential. Channel activation enables transportation of potassium ions down their elec
Externí odkaz:
https://doaj.org/article/00b3951856114dd0807dc85057d5ea47
Publikováno v:
Molecules, Vol 25, Iss 7, p 1654 (2020)
Multidrug resistance (MDR) that occurs in cancer cells constitutes one of the major reasons for chemotherapy failure. The main molecular mechanism of MDR is overexpression of protein transporters from the ATP-binding cassette (ABC) superfamily, such
Externí odkaz:
https://doaj.org/article/ed476e311eee48a7855e962b7b458180
Publikováno v:
Plant Pathology. 71:1335-1343
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8df42ef17a3d5f4057a9fd201b083a25
https://doi.org/10.1111/ppa.13570
https://doi.org/10.1111/ppa.13570
Publikováno v:
Gene. 862:147261
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db4be47c48db0436bbbd4d23b3ded5d7
https://doi.org/10.1016/j.gene.2023.147261
https://doi.org/10.1016/j.gene.2023.147261
Autor:
Tomasz Janeczko, Anna Palko-Łabuz, Krystyna Michalak, Anna Uryga, Kamila Środa-Pomianek, Edyta Kostrzewa-Susłow, Andrzej Poła
Publikováno v:
Human & Experimental Toxicology. 39:262-275
Chalcones are naturally occurring compounds exhibiting biological activity through multiple mechanisms. Flavokawain B is one of chalcones found in kava plant. In our studies, we focused on the anticancer activity of flavokawain B in colorectal cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf66899d6bdd283e818d8cf228223bd9
https://doi.org/10.1177/0960327119882986
https://doi.org/10.1177/0960327119882986
Autor:
Fuliang Xie, Magdalena Pawełkowicz, Baohong Zhang, Zhimin Yin, Renata Lebecka, Zofia Murawska, Krystyna Michalak
Publikováno v:
Virus Research. 260:20-32
The present study demonstrates how different potato virus Y (PVY) strains affect the miRNA balance in tobacco cv. Samsun. The two prevalent strains PVYNTN and PVYN−Wi caused severe and mild veinal necrosis (VN) respectively, and the unique PVYZ-NTN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2674d109e03b720853c6115ee1d3e977
https://doi.org/10.1016/j.virusres.2018.11.002
https://doi.org/10.1016/j.virusres.2018.11.002