Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Krystyna M. Wozniak"'
Autor:
Barbara S. Slusher, Michael Polydefkis, Guido Cavaletti, Stuart C. Feinstein, Mary A. Jordan, Leslie Wilson, Christopher DesJardins, Sean Eckley, Krista Condon, Kenichi Nomoto, Bruce A. Littlefield, Brett M. Cook, Sara Semperboni, Eleonora Pozzi, Paola Alberti, Elisa Ballarini, Virginia Rodriguez-Menendez, Valentina A. Carozzi, Ying Liu, Ying Wu, James J. Vornov, Krystyna M. Wozniak
File contains description of supplementary methods used for sciatic nerve immunofluorescence data generation and quantification with Supplementary Fig 1 showing how raw fluorescence intensity values were normalized in order to compare levels of acety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c8fe14a2eaf120d0d4176f58a513a6
https://doi.org/10.1158/0008-5472.22417085
https://doi.org/10.1158/0008-5472.22417085
Autor:
Barbara S. Slusher, Michael Polydefkis, Guido Cavaletti, Stuart C. Feinstein, Mary A. Jordan, Leslie Wilson, Christopher DesJardins, Sean Eckley, Krista Condon, Kenichi Nomoto, Bruce A. Littlefield, Brett M. Cook, Sara Semperboni, Eleonora Pozzi, Paola Alberti, Elisa Ballarini, Virginia Rodriguez-Menendez, Valentina A. Carozzi, Ying Liu, Ying Wu, James J. Vornov, Krystyna M. Wozniak
Chemotherapy-induced peripheral neuropathy (CIPN) is a major cause of disability in cancer survivors. CIPN investigations in preclinical model systems have focused on either behaviors or acute changes in nerve conduction velocity (NCV) and amplitude,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ede1532c2b073e39e9d7c1ef288c76
https://doi.org/10.1158/0008-5472.c.6509738
https://doi.org/10.1158/0008-5472.c.6509738
Autor:
Barbara S. Slusher, Bruce A. Littlefield, Murray J. Towle, Satoru Hosokawa, Kazuhiro Hayakawa, Guido Cavaletti, Valentina Carozzi, Ying Wu, Rena G. Lapidus, Kenichi Nomoto, Krystyna M. Wozniak
Supplementary Figures 1-2 from Comparison of Neuropathy-Inducing Effects of Eribulin Mesylate, Paclitaxel, and Ixabepilone in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642054b413d52e50a1b379ba1a9e2809
https://doi.org/10.1158/0008-5472.22393887.v1
https://doi.org/10.1158/0008-5472.22393887.v1
Autor:
Barbara S. Slusher, Bruce A. Littlefield, Murray J. Towle, Satoru Hosokawa, Kazuhiro Hayakawa, Guido Cavaletti, Valentina Carozzi, Ying Wu, Rena G. Lapidus, Kenichi Nomoto, Krystyna M. Wozniak
Supplementary Figure Legends 1-2 from Comparison of Neuropathy-Inducing Effects of Eribulin Mesylate, Paclitaxel, and Ixabepilone in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6d8421f1334322e0c86943a411f57c
https://doi.org/10.1158/0008-5472.22393890.v1
https://doi.org/10.1158/0008-5472.22393890.v1
Autor:
Barbara S. Slusher, Bruce A. Littlefield, Murray J. Towle, Satoru Hosokawa, Kazuhiro Hayakawa, Guido Cavaletti, Valentina Carozzi, Ying Wu, Rena G. Lapidus, Kenichi Nomoto, Krystyna M. Wozniak
Chemotherapy-induced neurotoxicity is a significant problem associated with successful treatment of many cancers. Tubulin is a well-established target of antineoplastic therapy; however, tubulin-targeting agents, such as paclitaxel and the newer epot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46d939d6015bb8b918391bb568c869ee
https://doi.org/10.1158/0008-5472.c.6503901.v1
https://doi.org/10.1158/0008-5472.c.6503901.v1
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e102936 (2014)
Pyridoxine is used as a supplement for treating conditions such as vitamin deficiency as well as neurological disorders such as depression, epilepsy and autism. A significant neurologic complication of pyridoxine therapy is peripheral neuropathy thou
Externí odkaz:
https://doaj.org/article/e251711e2780449cb86f64a274bfb576
Autor:
Mary Ann Jordan, Duncan A. Proctor, Barbara S. Slusher, Stuart C. Feinstein, Bruce A. Littlefield, Ying Wu, Leslie Wilson, Krystyna M. Wozniak, R. B. Bromberg, Brett M. Cook
Publikováno v:
Neurotoxicity Research. 34:677-692
The reversibility of chemotherapy-induced peripheral neuropathy (CIPN), a disabling and potentially permanent side effect of microtubule-targeting agents (MTAs), is becoming an increasingly important issue as treatment outcomes improve. The molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e756cb0518fbe76748deb1b7c2f5c9a9
https://doi.org/10.1007/s12640-018-9929-8
https://doi.org/10.1007/s12640-018-9929-8
Autor:
James J. Vornov, Ying Wu, Kenichi Nomoto, Larisa Reyderman, Nancy Wong, Christopher DesJardins, Yanke Yu, Bruce A. Littlefield, Krystyna M. Wozniak, W. George Lai, Barbara S. Slusher
Publikováno v:
Cancer Research. 76:3332-3339
Chemotherapy-induced peripheral neuropathy is a dose-limiting side effect of many antineoplastic agents, but the mechanisms underlying the toxicities are unclear. At their MTDs, the microtubule-binding drugs paclitaxel and ixabepilone induce more sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2354bf4cbf0c4beb2e17561324defff3
https://doi.org/10.1158/0008-5472.can-15-2525
https://doi.org/10.1158/0008-5472.can-15-2525
Autor:
Rana Rais, Krystyna M. Wozniak, Niyada Hin, Zora Novakova, Takashi Tsukamoto, Jan Vávra, Camilo Rojas, Barbara S. Slusher, Andrej Jancarik, Jiri Pavlicek, Ying Wu, Pavel Majer, Dana Ferraris, Cyril Barinka, Barbora Havlinova, Jakub Ptacek
Publikováno v:
Journal of Medicinal Chemistry. 59:4539-4550
Inhibition of glutamate carboxypeptidase II (GCPII) is effective in preclinical models of neurological disorders associated with excessive activation of glutamatergic systems. Here we report synthesis, structural characterization, and biological acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b15e3c98cc5e6dc9020bad74e3d7ac
https://doi.org/10.1021/acs.jmedchem.5b01806
https://doi.org/10.1021/acs.jmedchem.5b01806
Autor:
Alessia Chiorazzi, Ying Wu, Rana Rais, Virginia Rodriguez-Menendez, Krystyna M. Wozniak, Michael Polydefkis, Eleonora Pozzi, Annalisa Canta, Mohamed H. Farah, Guido Cavaletti, Cristina Meregalli, Alexandra J. Gadiano, Barbara S. Slusher, Paola Alberti, Laura Monza, G Fumagalli, James J. Vornov, Ying Liu, Claudio Pietra
Publikováno v:
European journal of pharmacology. 840
Chemotherapy-Induced Peripheral Neurotoxicity (CIPN) is often dose-limiting and impacts life quality and survival of cancer patients. Ghrelin agonists have neuroprotectant effects and may have a role in treating or preventing CIPN. We evaluated the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8140c23957893490b36494a7a9c64a32
https://pubmed.ncbi.nlm.nih.gov/30268665
https://pubmed.ncbi.nlm.nih.gov/30268665