Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Krystyna Konopka"'
Publikováno v:
Pathogens, Vol 10, Iss 12, p 1599 (2021)
Fusion of lipid-enveloped viruses with the cellular plasma membrane or the endosome membrane is mediated by viral envelope proteins that undergo large conformational changes following binding to receptors. The HIV-1 fusion protein gp41 undergoes a tr
Externí odkaz:
https://doaj.org/article/5ce1bc201f68413a89199261f0885c0f
Autor:
Nejat Düzgüneş, Krystyna Konopka
Publikováno v:
Pharmaceutics, Vol 11, Iss 6, p 255 (2019)
Predictions made soon after the introduction of human immunodeficiency virus type-1 (HIV-1) protease inhibitors about potentially eradicating the cellular reservoirs of HIV-1 in infected individuals were too optimistic. The ability of the HIV-1 genom
Externí odkaz:
https://doaj.org/article/a82cf1b4b5754f7ba2732a2f22e18a46
Autor:
Krystyna Konopka, Nejat Düzgüneş
Publikováno v:
Medical Research Archives. 8
Lipid-enveloped viruses, including HIV-1 and SARS-CoV-2, infect their host cells by fusion either directly with the plasma membrane or with the endosome membrane following endocytosis. Biophysical insights into the conformational changes of viral fus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b22eb5f1ee5aae3f534de1df108aae22
https://doi.org/10.18103/mra.v8i9.2244
https://doi.org/10.18103/mra.v8i9.2244
Autor:
Krystyna Konopka, Jadwiga Mielcarek, Tomasz Goslinski, Piotr Gierlich, Wojciech Szczolko, Paulina Skupin-Mrugalska, Nejat Düzgüneş
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 353:445-457
Three 2-(morpholin-4-yl)ethoxy-substituted phthalocyanines with zinc(II) or magnesium(II) ion in the core were subjected to optical and photochemical studies, and their photodynamic activity against oral cancer cell lines was evaluated. Phthalocyanin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0812daa240799a2d1c02b0401d15fc65
https://doi.org/10.1016/j.jphotochem.2017.12.005
https://doi.org/10.1016/j.jphotochem.2017.12.005
Autor:
Stefan Jurga, Dariusz T. Mlynarczyk, Lukasz Popenda, Wojciech Szczolko, Lukasz Sobotta, Tomasz Goslinski, Magdalena Stolarska, Jadwiga Mielcarek, Nejat Düzgüneş, Krystyna Konopka, Jaroslaw Piskorz
Publikováno v:
Bioorganic chemistry. 96
An important subgroup within the porphyrazine (Pz) family constitutes seco-porphyrazines, in the chemical structure of which one pyrrole unit is opened in the oxidative process. So far, there are only limited data on N-seco- and C-seco-Pzs. Here, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c210d025aee0b2c71c92ba97307b71ed
https://pubmed.ncbi.nlm.nih.gov/32044518
https://pubmed.ncbi.nlm.nih.gov/32044518
Autor:
Krystyna Konopka, Nejat Düzgüneş
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 11, Iss 6, p 255 (2019)
Pharmaceutics, Vol 11, Iss 6, p 255 (2019)
Predictions made soon after the introduction of human immunodeficiency virus type-1 (HIV-1) protease inhibitors about potentially eradicating the cellular reservoirs of HIV-1 in infected individuals were too optimistic. The ability of the HIV-1 genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7cb7c2135c92daba2e2a78399f9e2e0
http://europepmc.org/articles/PMC6631149
http://europepmc.org/articles/PMC6631149
Publikováno v:
Methods in Molecular Biology ISBN: 9781493989218
Suicide gene therapy induced by the Herpes Simplex Virus thymidine kinase/ganciclovir (HSV-tk/GCV) system has been utilized to successfully treat various cancers. We describe TransfeX-mediated transfection of pCMV.Luc into HeLa cervical carcinoma and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1018f8352fd98f24c6131be806e969d
https://doi.org/10.1007/978-1-4939-8922-5_14
https://doi.org/10.1007/978-1-4939-8922-5_14
Autor:
Krystyna Konopka, Paulina Skupin-Mrugalska, Jaroslaw Piskorz, Jadwiga Mielcarek, Tomasz Goslinski, Nejat Düzgüneş
Publikováno v:
Therapeutic delivery. 9(11)
The photodynamic reaction involves the light-induced generation of an excited state in a photosensitizer molecule (PS), which then results in the formation of reactive oxygen species in the presence of oxygen, or a direct modification of a cellular m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5e67c9bd825990f10bd07192a03fae
https://pubmed.ncbi.nlm.nih.gov/30444459
https://pubmed.ncbi.nlm.nih.gov/30444459
Autor:
Jaroslaw Piskorz, Krystyna Konopka, Jadwiga Mielcarek, Dariusz T. Mlynarczyk, Nejat Düzgüneş, Wojciech Szczolko
Publikováno v:
Journal of inorganic biochemistry. 184
Photodynamic therapy of cancer comprises the activation of photosensitizer molecules delivered to cancer cells, to generate reactive oxygen species that mediate cytotoxicity. In this study, previously synthesized dendritic magnesium tribenzoporphyraz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948f16a62947169086b6f82125de4937
https://pubmed.ncbi.nlm.nih.gov/29679798
https://pubmed.ncbi.nlm.nih.gov/29679798
Autor:
Tomasz Goslinski, Paulina Skupin-Mrugalska, Marek Murias, Tomasz Koczorowski, Anna Teubert, Nejat Düzgüneş, Jadwiga Mielcarek, Malgorzata Kucinska, Jolanta Dlugaszewska, Wojciech Szczolko, Krystyna Konopka
Publikováno v:
Journal of inorganic biochemistry. 172
Photodynamic therapy involves the use of a photosensitizer that is irradiated with visible light in the presence of oxygen, resulting in the formation of reactive oxygen species. A novel phthalocyanine derivative, the quaternary iodide salt of magnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db3024ab4cf7f28115e921b98b11d5d
https://pubmed.ncbi.nlm.nih.gov/28433834
https://pubmed.ncbi.nlm.nih.gov/28433834