Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Krystsina Kucharava"'
Autor:
Marijana Sekulic-Jablanovic, Vesna Petkovic, Matthew B Wright, Krystsina Kucharava, Nathan Huerzeler, Soledad Levano, Yves Brand, Katharina Leitmeyer, Andrea Glutz, Alexander Bausch, Daniel Bodmer
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188596 (2017)
Various insults cause ototoxicity in mammals by increasing oxidative stress leading to apoptosis of auditory hair cells (HCs). The thiazolidinediones (TZDs; e.g., pioglitazone) and fibrate (e.g., fenofibrate) drugs are used for the treatment of diabe
Externí odkaz:
https://doaj.org/article/0bedfaffde8b473f8375b5afaeb10bd7
Autor:
Nathan Huerzeler, Marijana Sekulic-Jablanovic, Matthew B. Wright, Vesna Petkovic, Krystsina Kucharava, Daniel Bodmer
Publikováno v:
Audiology and Neurotology. 24:65-76
Insulin receptors are expressed on nerve cells in the mammalian brain, but little is known about insulin signaling and the expression of the insulin receptor (IR) and glucose transporters in the cochlea. We performed immunohistochemistry and gene/pro
Autor:
Daniel Guido Fuster, Xunde Xian, Vesna Petkovic, Andrea Glutz, Marijana Sekulic-Jablanovic, Giuseppe Albano, Daniel Bodmer, Yves Brand, Joachim Herz, Krystsina Kucharava
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Kucharava, Krystsina; Brand, Yves; Albano, Giuseppe; Sekulic-Jablanovic, Marijana; Glutz, Andrea; Xian, Xunde; Herz, Joachim; Bodmer, Daniel; Fuster, Daniel G.; Petkovic, Vesna (2020). Sodium-hydrogen exchanger 6 (NHE6) deficiency leads to hearing loss, via reduced endosomal signalling through the BDNF/Trk pathway. Scientific reports, 10(1), p. 3609. Springer Nature 10.1038/s41598-020-60262-5
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Kucharava, Krystsina; Brand, Yves; Albano, Giuseppe; Sekulic-Jablanovic, Marijana; Glutz, Andrea; Xian, Xunde; Herz, Joachim; Bodmer, Daniel; Fuster, Daniel G.; Petkovic, Vesna (2020). Sodium-hydrogen exchanger 6 (NHE6) deficiency leads to hearing loss, via reduced endosomal signalling through the BDNF/Trk pathway. Scientific reports, 10(1), p. 3609. Springer Nature 10.1038/s41598-020-60262-5
Acid-base homeostasis is critical for normal growth, development, and hearing function. The sodium–hydrogen exchanger 6 (NHE6), a protein mainly expressed in early and recycling endosomes, plays an important role in regulating organellar pH. Mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46863d5b6f85e621dc295175ecb1c4a4
Autor:
Marijana Sekulic-Jablanovic, Krystsina Kucharava, Lukas Horvath, Vesna Petkovic, Daniel Bodmer
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 2, Pp 1-14 (2019)
Cell Death and Disease, Vol 10, Iss 2, Pp 1-14 (2019)
Gentamicin is a widely used antibiotic for the treatment of gram-negative bacterial infections; however, its use often results in significant and permanent hearing loss. Hearing loss resulting from hair cell (HC) degeneration affects millions of peop
Autor:
Katharina Leitmeyer, Marijana Sekulic-Jablanovic, Nathan Huerzeler, Matthew Blake Wright, Bausch Alexander, Krystsina Kucharava, Daniel Bodmer, Soledad Levano, Andrea Glutz, Vesna Petkovic, Yves Brand
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0188596 (2017)
PLoS ONE, Vol 12, Iss 11, p e0188596 (2017)
Various insults cause ototoxicity in mammals by increasing oxidative stress leading to apoptosis of auditory hair cells (HCs). The thiazolidinediones (TZDs; e.g., pioglitazone) and fibrate (e.g., fenofibrate) drugs are used for the treatment of diabe