Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Krystin M. Samms"'
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101073- (2022)
Summary: Epithelial tissues sustain barrier function by removing and replacing aberrant or unfit cells. Here, we describe approaches to evaluate epithelial restorative capacity after inducing cell loss in zebrafish larvae. We provide details to quant
Externí odkaz:
https://doaj.org/article/1213ff88a5084842b1bf32807eb5f8b4
Autor:
Courtney K. Brock, Stephen T. Wallin, Oscar E. Ruiz, Krystin M. Samms, Amrita Mandal, Elizabeth A. Sumner, George T. Eisenhoffer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Damaged epithelial tissues are known to compensate for cell death through compensatory cell divisions to maintain epithelial integrity. Here, the authors show in living epithelia that dying cells stimulate adjacent stem cells to divide through caspas
Externí odkaz:
https://doaj.org/article/36038ed7967345729d64f073b9d12a1c
Autor:
Sebastian Wurster, Oscar E. Ruiz, Krystin M. Samms, Alexander M. Tatara, Nathaniel D. Albert, Philip H. Kahan, Anh Trinh Nguyen, Antonios G. Mikos, Dimitrios P. Kontoyiannis, George T. Eisenhoffer
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108896- (2021)
Summary: Severe and often fatal opportunistic fungal infections arise frequently following mucosal damage caused by trauma or cytotoxic chemotherapy. Interaction of fungal pathogens with epithelial cells that comprise mucosae is a key early event ass
Externí odkaz:
https://doaj.org/article/090b8750f4e64706818b17aa866b5303
Autor:
Alexander M. Tatara, Philip H. Kahan, Sebastian Wurster, Oscar E. Ruiz, Antonios G. Mikos, Dimitrios P. Kontoyiannis, Anh Trinh Nguyen, Nathaniel D. Albert, George T. Eisenhoffer, Krystin M. Samms
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108896-(2021)
Severe, often fatal, opportunistic fungal infections frequently arise following mucosal damage caused by trauma or cytotoxic chemotherapy. Interaction of fungal pathogens with epithelial cells that comprise mucosa is a key early event associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87d7790085b6c916465ee37b7fc69b2
https://pubmed.ncbi.nlm.nih.gov/33761358
https://pubmed.ncbi.nlm.nih.gov/33761358
Autor:
Oscar E. Ruiz, Elizabeth A. Sumner, Courtney K. Brock, Stephen T. Wallin, Amrita Mandal, George T. Eisenhoffer, Krystin M. Samms
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Epithelial tissues require the removal and replacement of damaged cells to sustain a functional barrier. Dying cells provide instructive cues that can influence surrounding cells to proliferate, but how these signals are transmitted to their healthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c2356028c041cd5d95ac34152ef29f
https://doi.org/10.1038/s41467-019-09010-6
https://doi.org/10.1038/s41467-019-09010-6
Autor:
Antonios G. Mikos, Alexander M. Tatara, Oscar E. Ruiz, Nathaniel D. Albert, Anh Kim Nguyen, George T. Eisenhoffer, Philip H. Kahan, Krystin M. Samms, Dimitrios P. Kontoyiannis, Sebastian Wurster
Publikováno v:
Open Forum Infectious Diseases
Background Efficient animal models are needed in order to investigate fungal pathogenicity and antifungal therapy in the context of epithelial injury, e.g., due to anticancer chemotherapy. Using a Gal4 enhancer trap (GET) zebrafish line facilitating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2664592dc82fab2e7b83a030e593e784
https://doi.org/10.1093/ofid/ofz360.2285
https://doi.org/10.1093/ofid/ofz360.2285