Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Krystiana A Krzyśko"'
Autor:
Joanna Krajewska, Piotr Chyży, Krzysztof Durka, Patrycja Wińska, Krystiana A. Krzyśko, Sergiusz Luliński, Agnieszka E. Laudy
Publikováno v:
Molecules, Vol 28, Iss 21, p 7362 (2023)
Over 30 compounds, including para-, meta-, and ortho-phenylenediboronic acids, ortho-substituted phenylboronic acids, benzenetriboronic acids, di- and triboronated thiophenes, and pyridine derivatives were investigated as potential β-lactamase inhib
Externí odkaz:
https://doaj.org/article/f739ebfca5a647fe9e730b5edb321240
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract MMP-9 plays a number of important physiological functions but is also responsible for many pathological processes, including cancer invasion, metastasis, and angiogenesis. It is, therefore, crucial to understand its enzymatic activity, inclu
Externí odkaz:
https://doaj.org/article/31d6a2a981a641369c72f07ab9878909
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Recently, molecular covalent docking has been extensively developed to design new classes of inhibitors that form chemical bonds with their biological targets. This strategy for the design of such inhibitors, in particular boron-based inhibitors, hol
Externí odkaz:
https://doaj.org/article/7489973e0a1e4dc88653f005be97c89c
Autor:
Małgorzata Beręsewicz, Anna Boratyńska-Jasińska, Łukasz Charzewski, Maria Kawalec, Dagmara Kabzińska, Andrzej Kochański, Krystiana A Krzyśko, Barbara Zabłocka
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169999 (2017)
Charcot-Marie-Tooth disease type 2A (CMT2A) is an autosomal dominant axonal peripheral neuropathy caused by mutations in the mitofusin 2 gene (MFN2). Mitofusin 2 is a GTPase protein present in the outer mitochondrial membrane and responsible for regu
Externí odkaz:
https://doaj.org/article/cfaefa1212b744a1b83eca09b8429cd1
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences
Recently, molecular covalent docking has been extensively developed to design new classes of inhibitors that form chemical bonds with their biological targets. This strategy for the design of such inhibitors, in particular boron-based inhibitors, hol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbeb51c260143b1af63bb2776916f34
https://www.frontiersin.org/articles/10.3389/fmolb.2021.633181/full
https://www.frontiersin.org/articles/10.3389/fmolb.2021.633181/full
Autor:
Barbara Zabłocka, Łukasz Charzewski, Krystiana A. Krzyśko, Małgorzata Beręsewicz, Andrzej Kochański
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Charcot-Marie-Tooth disease type 2A (CMT2A) is an autosomal dominant neuropathy caused by mutations in the mitofusin 2 gene (MFN2). More than 100 MFN2 gene mutations have been reported so far, with majority located within the GTPase domain encoding r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9d0eac9180183328705be870f39896
http://link.springer.com/article/10.1038/s41598-018-35133-9
http://link.springer.com/article/10.1038/s41598-018-35133-9
Autor:
Krystiana A. Krzyśko, Karolina Stępień, Krzysztof Durka, Stefan Tyski, Sergiusz Luliński, Łukasz Charzewski, Agnieszka E. Laudy, Mateusz Urban
Publikováno v:
European journal of medicinal chemistry. 171
A series of 22 benzosiloxaboroles, silicon analogues of strong antimicrobial agents - benzoxaboroles, have been synthesized and tested against β-lactamases KPC- and pAmpC-producing strains of Gram-negative rods. Comprehensive structural-property rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84b109eb9e2a99f5b6e6168e6245f6b
https://pubmed.ncbi.nlm.nih.gov/30904754
https://pubmed.ncbi.nlm.nih.gov/30904754
Autor:
Anna Boratyńska-Jasińska, Łukasz Charzewski, Barbara Zabłocka, Krystiana A. Krzyśko, Andrzej Kochański, Maria Kawalec, Dagmara Kabzińska, Małgorzata Beręsewicz
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0169999 (2017)
PLoS ONE, Vol 12, Iss 1, p e0169999 (2017)
Charcot-Marie-Tooth disease type 2A (CMT2A) is an autosomal dominant axonal peripheral neuropathy caused by mutations in the mitofusin 2 gene (MFN2). Mitofusin 2 is a GTPase protein present in the outer mitochondrial membrane and responsible for regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e70b6d28664132c06d74035fc64a9c
http://europepmc.org/articles/PMC5226824
http://europepmc.org/articles/PMC5226824
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1758:537-544
Mechanical unfolding of single bacteriorhodopsins from a membrane bilayer is studied using molecular dynamics simulations. The initial conformation of the lipid membrane is determined through all-atom simulations and then its coarse-grained represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ba0608ac049d5a5d12583688ccd67a
https://doi.org/10.1016/j.bbamem.2006.03.028
https://doi.org/10.1016/j.bbamem.2006.03.028
Publikováno v:
Challenges and Advances in Computational Chemistry and Physics ISBN: 9781402053719
Dimerization, and more generally oligomerization, of G protein-coupled receptors (GPCRs) is experimentally proven and possibly all GPCRs act in oligomeric form. The coupling with G protein, phosphorylation by kinase and binding to arrestin what start
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::679ffd2a2a4615c18e9a26b8d895afe5
https://doi.org/10.1007/1-4020-5372-x_11
https://doi.org/10.1007/1-4020-5372-x_11
