Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Krystelle Nganou-Makamdop"'
Publikováno v:
Pathogens and Immunity, Vol 9, Iss 1 (2024)
It is widely acknowledged that HIV infection results in disruption of the gut’s mucosal integrity partly due a profound loss of gastrointestinal CD4+ T cells that are targets of the virus. In addition, systemic inflammation and immune activation th
Externí odkaz:
https://doaj.org/article/5d948931ec8a4ec8ade62933c20a8b4a
Autor:
Boutaina El Kenz, Katja G. Schmidt, Victoria K. Ogungbemi-Alt, Silke Bergmann, Philipp Steininger, Klaus Korn, Bernd Spriewald, Ellen G. Harrer, Krystelle Nganou-Makamdop, Thomas Harrer
Publikováno v:
Viruses, Vol 15, Iss 2, p 567 (2023)
The analysis of T-cell responses in HIV-1-infected controllers may contribute to a better understanding of the protective components of the immune system. Here, we analyzed the HIV-1-specific T-cell response in a 59-year-old HIV-1-infected controller
Externí odkaz:
https://doaj.org/article/1cf176c9fc654103bbae9ff2076fcdc1
Autor:
Natalie Fischhaber, Moritz Schmiedeberg, Sabrina Kübel, Ellen G. Harrer, Thomas Harrer, Krystelle Nganou-Makamdop
Publikováno v:
Vaccines, Vol 11, Iss 2, p 211 (2023)
Despite antiretroviral therapy (ART), immune exhaustion persists in HIV infection and limits T cell responses to HIV or other pathogens. Moreover, HIV infection results in the loss of pre-existing immunity. Here, we investigated the effect of blockin
Externí odkaz:
https://doaj.org/article/e4746f8591a74104821cb67586193048
Autor:
Shida Shangguan, Philip K Ehrenberg, Aviva Geretz, Lauren Yum, Gautam Kundu, Kelly May, Slim Fourati, Krystelle Nganou-Makamdop, LaTonya D Williams, Sheetal Sawant, Eric Lewitus, Punnee Pitisuttithum, Sorachai Nitayaphan, Suwat Chariyalertsak, Supachai Rerks-Ngarm, Morgane Rolland, Daniel C Douek, Peter Gilbert, Georgia D Tomaras, Nelson L Michael, Sandhya Vasan, Rasmi Thomas
Publikováno v:
eLife, Vol 10 (2021)
A gene signature was previously found to be correlated with mosaic adenovirus 26 vaccine protection in simian immunodeficiency virus and simian-human immunodeficiency virus challenge models in non-human primates. In this report, we investigated the p
Externí odkaz:
https://doaj.org/article/81dfbbada87149d49aa3e55c7de54154
Autor:
Katja G. Schmidt, Krystelle Nganou-Makamdop, Matthias Tenbusch, Boutaina El Kenz, Clara Maier, Dennis Lapuente, Klaus Überla, Bernd Spriewald, Silke Bergmann, Ellen G. Harrer, Thomas Harrer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The beta-coronavirus SARS-CoV-2 induces severe disease (COVID-19) mainly in elderly persons with risk factors, whereas the majority of patients experience a mild course of infection. As the circulating common cold coronaviruses OC43 and HKU1 share so
Externí odkaz:
https://doaj.org/article/7fb6cf550ac54962b6c77f2cb6f30987
Autor:
Katja G. Schmidt, Ellen G. Harrer, Koray Tascilar, Sabrina Kübel, Boutaina El Kenz, Fabian Hartmann, David Simon, Georg Schett, Krystelle Nganou-Makamdop, Thomas Harrer
Publikováno v:
Viruses, Vol 14, Iss 3, p 651 (2022)
Only limited data are available regarding the immunogenicity of the BNT162b2 mRNA vaccine in HIV-1+ patients. Therefore, we investigated the humoral immune response after BNT162b2-mRNA vaccination or SARS-CoV-2 infection in HIV-1+ patients on antiret
Externí odkaz:
https://doaj.org/article/9ac5a065b8a14a4da8ffcc68dc223db8
Autor:
Daniel T Claiborne, Eileen P Scully, Christine D Palmer, Jessica L Prince, Gladys N Macharia, Jakub Kopycinski, Clive M Michelo, Howard W Wiener, Rachel Parker, Krystelle Nganou-Makamdop, Daniel Douek, Marcus Altfeld, Jill Gilmour, Matt A Price, Jianming Tang, William Kilembe, Susan A Allen, Eric Hunter
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007981 (2019)
Despite extensive research on the mechanisms of HLA-mediated immune control of HIV-1 pathogenesis, it is clear that much remains to be discovered, as exemplified by protective HLA alleles like HLA-B*81 which are associated with profound protection fr
Externí odkaz:
https://doaj.org/article/3129ca96dec349d19e188585cbaa024d
Autor:
Krystelle Nganou-Makamdop, James M Billingsley, Zachary Yaffe, Gregory O'Connor, Gregory K Tharp, Amy Ransier, Farida Laboune, Rodrigo Matus-Nicodemos, Andrea Lerner, Lavina Gharu, Jennifer M Robertson, Mandy L Ford, Martin Schlapschy, Nadine Kuhn, Alexandra Lensch, Jeffrey Lifson, Martha Nason, Arne Skerra, Gideon Schreiber, Steven E Bosinger, Daniel C Douek
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007246 (2018)
Chronic activation of the immune system in HIV infection is one of the strongest predictors of morbidity and mortality. As such, approaches that reduce immune activation have received considerable interest. Previously, we demonstrated that administra
Externí odkaz:
https://doaj.org/article/222e9d607de04416ad02ccb59781e2f1
Autor:
Krystelle Nganou-Makamdop, Geert-Jan van Gemert, Theo Arens, Cornelus C Hermsen, Robert W Sauerwein
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36508 (2012)
Protection against P. berghei malaria can successfully be induced in mice by immunization with both radiation attenuated sporozoites (RAS) arresting early during liver stage development, or sporozoites combined with chloroquine chemoprophylaxis (CPS)
Externí odkaz:
https://doaj.org/article/49c8d7efdf5249419bf5a4cc3a94627c
Autor:
Katja G. Schmidt, Ellen G. Harrer, Verena Schönau, David Simon, Arnd Kleyer, Philipp Steininger, Klaus Korn, Georg Schett, Carina S. Knobloch, Krystelle Nganou-Makamdop, Thomas Harrer
Publikováno v:
Infection.
Purpose The Ad26.COV2.S vaccine is a replication-incompetent human adenovirus type 26 vector encoding the SARS-CoV-2 spike protein. In a phase 1-2a trial, a single dose of Ad26.COV2.S induced SARS-CoV-2 spike-specific antibodies in ≥ 96% of healthy