Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Krystal K Lum"'
Autor:
Zachory M Park, Abigail J Sporer, Katherine Kraft, Krystal K Lum, Edith Blackman, Ethan Belnap, Christopher M Yellman, Mark D Rose
Publikováno v:
PLoS Genetics, Vol 19, Iss 8, p e1010896 (2023)
KAR4, the yeast homolog of the mammalian mRNA N6A-methyltransferase complex component METTL14, is required for two disparate developmental programs in Saccharomyces cerevisiae: mating and meiosis. To understand KAR4's role in yeast mating and meiosis
Externí odkaz:
https://doaj.org/article/04a060d5f391487a8c1f925cbf8232fc
Autor:
Alexander M Price, Robert T Steinbock, Richard Lauman, Matthew Charman, Katharina E Hayer, Namrata Kumar, Edwin Halko, Krystal K Lum, Monica Wei, Angus C Wilson, Benjamin A Garcia, Daniel P Depledge, Matthew D Weitzman
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010797 (2022)
Adenovirus is a common human pathogen that relies on host cell processes for transcription and processing of viral RNA and protein production. Although adenoviral promoters, splice junctions, and polyadenylation sites have been characterized using lo
Externí odkaz:
https://doaj.org/article/eaab36792be84a51a07f2ccdca52cc19
Autor:
Joseph M. Dybas, Krystal K. Lum, Katarzyna Kulej, Emigdio D. Reyes, Richard Lauman, Matthew Charman, Caitlin E. Purman, Robert T. Steinbock, Nicholas Grams, Alexander M. Price, Lydia Mendoza, Benjamin A. Garcia, Matthew D. Weitzman
Publikováno v:
mSystems, Vol 6, Iss 4 (2021)
ABSTRACT Viral infections are associated with extensive remodeling of the cellular proteome. Viruses encode gene products that manipulate host proteins to redirect cellular processes or subvert antiviral immune responses. Adenovirus (AdV) encodes pro
Externí odkaz:
https://doaj.org/article/8263a46ee7ba41df86e9a00e6d03a9fc
Autor:
Matthew Charman, Nicholas Grams, Namrata Kumar, Edwin Halko, Joseph M. Dybas, Amber Abbott, Krystal K. Lum, Daniel Blumenthal, Elene Tsopurashvili, Matthew D. Weitzman
Publikováno v:
Nature. 616:332-338
Autor:
Bokai Song, Xinlei Sheng, Joshua L. Justice, Krystal K. Lum, Peter J. Metzger, Katelyn C. Cook, James C. Kostas, Ileana M. Cristea
Publikováno v:
Science Advances. 9
Communication between infected cells and cells in the surrounding tissue is a determinant of viral spread. However, it remains unclear how cells in close or distant proximity to an infected cell respond to primary or secondary infections. We establis
Publikováno v:
mSystems. 7(3)
Human cells identify invading pathogens and activate immune signaling pathways through a wide array of pattern recognition receptors, including DNA sensors. The interferon-inducible protein 16 (IFI16) is a nuclear DNA sensor that recognizes double-st
Publikováno v:
Mol Cell Proteomics
The cyclic GMP-AMP synthase (cGAS) protein is a pattern-recognition receptor of the mammalian innate immune system that is recognized as a main cytosolic sensor of pathogenic or damaged DNA. cGAS DNA binding initiates catalytic production of the seco
Autor:
Matthew Charman, Richard Lauman, Joseph M Dybas, Nicholas Grams, Alexander M. Price, Caitlin E. Purman, Matthew D. Weitzman, Emigdio D. Reyes, Robert T Steinbock, Benjamin A. Garcia, Krystal K Lum, Katarzyna Kulej, Lydia Mendoza
Publikováno v:
mSystems, Vol 6, Iss 4 (2021)
Viral infections are associated with extensive remodeling of the cellular proteome. Viruses encode gene products that manipulate host proteins to redirect cellular processes or subvert antiviral immune responses. Adenovirus (AdV) encodes proteins fro
Publikováno v:
mSystems, Vol 6, Iss 3 (2021)
mSystems
mSystems
DNA sensors are critical components of innate immunity that enable cells to recognize infection by pathogens with DNA genomes. The interferon-inducible protein X (IFIX), a member of the PYHIN protein family, is a DNA sensor capable of promoting immun
Publikováno v:
Molecular & Cellular Proteomics. 18:S92-S113
Huntington's disease (HD) is a monogenic disorder, driven by the expansion of a trinucleotide (CAG) repeat within the huntingtin (Htt) gene and culminating in neuronal degeneration in the brain, predominantly in the striatum and cortex. Histone deace