Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Krystal J Vail"'
Autor:
Krystal J Vail, Bibiana Petri da Silveira, Samantha L Bell, Noah D Cohen, Angela I Bordin, Kristin L Patrick, Robert O Watson
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009888 (2021)
Rhodococcus equi is a major cause of foal pneumonia and an opportunistic pathogen in immunocompromised humans. While alveolar macrophages constitute the primary replicative niche for R. equi, little is known about how intracellular R. equi is sensed
Externí odkaz:
https://doaj.org/article/2ac9b5fc418b491eb0a4f4d8c3eba144
Autor:
Chi G Weindel, Samantha L Bell, Krystal J Vail, Kelsi O West, Kristin L Patrick, Robert O Watson
Publikováno v:
eLife, Vol 9 (2020)
The Parkinson’s disease (PD)-associated gene leucine-rich repeat kinase 2 (LRRK2) has been studied extensively in the brain. However, several studies have established that mutations in LRRK2 confer susceptibility to mycobacterial infection, suggest
Externí odkaz:
https://doaj.org/article/4caa4bf04ba84861995ba7c4bd7c84fd
Autor:
Krystal J. Vail, Rodolfo Madrigal, Kevin Washburn, Juan Romano, John F. Edwards, Raquel Rech, Josue Delgado
Publikováno v:
Journal of the American Veterinary Medical Association. 259:45-48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ae10454bd78eaab357d977b7c87665
https://doi.org/10.2460/javma.259.1.45
https://doi.org/10.2460/javma.259.1.45
The Fragile X Syndrome‐Related Protein, FMRP, Modulates Innate Immune Gene Expression in Macrophages
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f32db3e4d46b0a9ee3f8da3478549f8
https://doi.org/10.1096/fasebj.2022.36.s1.r5210
https://doi.org/10.1096/fasebj.2022.36.s1.r5210
Autor:
Jason Karpac, Baoyu Zhao, Pingwei Li, Chi G Weindel, Cory Mabry, Kristin L. Patrick, Eduardo R. Martinez, Phillip West, Aja K. Coleman, Jordan J VanPortfliet, Krystal J Vail, Xiao Zhao, Robert O. Watson, Samantha L Bell
SUMMARYHuman mutations in mitochondrial-associated genes are associated with inflammatory diseases and susceptibility to infection. However, their mechanistic contributions to immune outcomes remain ill-defined. We discovered that the disease-associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9e2f7252780f4ed937aacbe248e920a
https://doi.org/10.1101/2021.11.18.469014
https://doi.org/10.1101/2021.11.18.469014
Autor:
A.E. Yanchik, Dominique J Wiener, Krystal J Vail, Lauren W. Stranahan, Brian F. Porter, Carolyn E. Arnold, L.M. Richardson
Publikováno v:
J Comp Pathol
Mycobacterial infections in horses are uncommon, but are caused most frequently by Mycobacterium bovis of the Mycobacterium tuberculosis complex or Mycobacterium avium of the M. avium complex. Disease caused by Mycobacterium intracellulare, the secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92dc175dfbf09aedc5cccf8eafdcdf7
https://doi.org/10.1016/j.jcpa.2019.04.001
https://doi.org/10.1016/j.jcpa.2019.04.001
Autor:
Philippa M. Gibbons, Eva Furrow, Raquel R. Rech, Tasha Likavec, Krystal J Vail, Katie M. Minor, Nicole M. Tate
Publikováno v:
Journal of Veterinary Internal Medicine
A 2‐year‐old mixed breed goat was presented for a 1‐day history of anorexia and 1 week of weight loss. Serum biochemistry disclosed severe azotemia. Abdominal ultrasound examination showed decreased renal corticomedullary distinction, poor visu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596e29b921388c633687e1e93af2d59f
https://doi.org/10.1111/jvim.15431
https://doi.org/10.1111/jvim.15431
Autor:
Chi G. Weindel, Eduardo L. Martinez, Xiao Zhao, Cory J. Mabry, Samantha L. Bell, Krystal J. Vail, Aja K. Coleman, Jordyn J. VanPortfliet, Baoyu Zhao, Allison R. Wagner, Sikandar Azam, Haley M. Scott, Pingwei Li, A. Phillip West, Jason Karpac, Kristin L. Patrick, Robert O. Watson
Publikováno v:
Cell. 185:3214-3231.e23
Although mutations in mitochondrial-associated genes are linked to inflammation and susceptibility to infection, their mechanistic contributions to immune outcomes remain ill-defined. We discovered that the disease-associated gain-of-function allele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1c9c6f5595b9edba7b01127d4e15a6
https://doi.org/10.1016/j.cell.2022.06.038
https://doi.org/10.1016/j.cell.2022.06.038
Autor:
Kristin L. Patrick, Allison R Wagner, Robert O. Watson, Krystal J Vail, Haley M. Scott, Kelsi O West, Kaitlin Carter
Pathogen sensing via pattern recognition receptors triggers massive reprogramming of macro-phage gene expression. While the signaling cascades and transcription factors that activate these responses are well-known, the role of post-transcriptional RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cca9f00999165dd60999801fda84f470
https://doi.org/10.1101/2020.12.06.413690
https://doi.org/10.1101/2020.12.06.413690
Autor:
Chi Gidley Weindel, Xiao Zhao, Eduardo Martinez, Samantha L. Bell, Krystal J. Vail, Aja K. Coleman, Jordyn J. VanPortfliet, Cory J. Mabry, Pingwei Li, A. Phillip West, Jason Karpac, Kristin L. Patrick, Robert O. Watson
Publikováno v:
The Journal of Immunology. 208:52.06-52.06
Human genetic variants associated with mitochondrial dysfunction have been linked to chronic inflammatory diseases as well as susceptibility to infection. However, the mechanistic impact that these variants have on the immune system is poorly underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0be09cf2153099729e7d2fbd26eea93
https://doi.org/10.4049/jimmunol.208.supp.52.06
https://doi.org/10.4049/jimmunol.208.supp.52.06