Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Krystal Colon"'
Autor:
Jocelyn Rivera-Ortiz, Jessalyn Pla-Tenorio, Myrella L. Cruz, Krystal Colon, Jaileene Perez-Morales, Julio A. Rodriguez, Jorge Martinez-Sicari, Richard J. Noel
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Combination antiretroviral therapy (cART) targets viral replication, but early viral protein production by astrocytes may still occur and contribute to the progression of HIV-1 associated neurocognitive disorders and secondary complications seen in p
Externí odkaz:
https://doaj.org/article/267a0a22d33e47db9920e0cb21afb3f1
Autor:
Jocelyn Rivera, Raymond A Isidro, Raisa Y Loucil-Alicea, Myrella L Cruz, Caroline B Appleyard, Angel A Isidro, Gladys Chompre, Krystal Colon-Rivera, Richard J Noel
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225760 (2019)
Even though HIV-1 replication can be suppressed by combination antiretroviral therapy (cART) inflammatory processes still occur, contributing to comorbidities. Comorbidities are attributed to variety of factors, including HIV-1 mediated inflammation.
Externí odkaz:
https://doaj.org/article/af8cd97087084fe280f6a06a900b636c
Autor:
Ian Frank, Luis J. Montaner, Pablo Tebas, Emmanouil Papasavvas, Karam Mounzer, Roger Keith Reeves, Kyle Kroll, Costin Tomescu, Krystal Colon
Publikováno v:
Eur J Immunol
The potential of immunotherapy strategies utilizing BNAbs such as 3BNC117 and 10-1074 to limit viral replication while also facilitating clearance of HIV infected cells has heightened interest in identifying the predominant NK effector subset(s) capa
Autor:
Costin Tomescu, Krystal Colon, David S. Metzger, David W. Speicher, Mack Taylor, Peter R. Smith, Luis J. Montaner
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 80:234-241
Background HIV-exposed seronegative people who inject drugs (HESN-PWID) have been shown to have increased natural killer (NK) cell and myeloid activation when compared with control donors. Methods We investigated potential mechanisms maintaining NK a
Autor:
Dana Brown, Tiffany Dominique, Dwight L. Evans, Cécile Denis, Knashawn H. Morales, Debora Dunbar, Ian Frank, Yi-Chien Ku, Peter R. Smith, Serguei Spitsin, Krystal Colon-Rivera, Menvekeh Daramay, Paul Crits-Christoph, Angus Culhane, Danielle Fiore, Chelsea D. Voytek, David S. Metzger, Michael B. Blank, Steven D. Douglas, Luis J. Montaner
Publikováno v:
AIDS and Behavior
Using a mobile research facility, we enrolled 141 opioid users from a neighborhood of Philadelphia, an urban epicenter of the opioid epidemic. Nearly all (95.6%) met DSM-5 criteria for severe opioid use disorder. The prevalence of HIV infection (8.5%
Autor:
Livio Azzoni, Krystal Colon, Mack Taylor, Luis J. Montaner, Peter R. Smith, Costin Tomescu, David S. Metzger
Publikováno v:
J Leukoc Biol
Previous literature suggests that acute opioid use results in the functional impairment of the immune response, thereby decreasing resistance to viral infection. Here, we assessed if innate and adaptive immune responses are compromised ex vivo in per
Autor:
Gabriel Borges-Vélez, Krystal Colon, Loyda M. Meléndez, Lester J. Rosario-Rodríguez, Karla Negron
Publikováno v:
Journal of Neuroimmune Pharmacology. 13:345-354
HIV-associated neurocognitive disorders (HAND) are prevalent despite combined antiretroviral therapy, affecting nearly half of HIV-infected patients worldwide. During HIV infection of macrophages secretion of the lysosomal protein, cathepsin B, is in
Autor:
Angel A. Isidro, Richard J. Noel, Jocelyn Rivera, Caroline B. Appleyard, Krystal Colon-Rivera, Raisa Y. Loucil-Alicea, Raymond A. Isidro, Myrella L Cruz, Gladys Chompre
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0225760 (2019)
PLoS ONE, Vol 14, Iss 11, p e0225760 (2019)
Even though HIV-1 replication can be suppressed by combination antiretroviral therapy (cART) inflammatory processes still occur, contributing to comorbidities. Comorbidities are attributed to variety of factors, including HIV-1 mediated inflammation.
Publikováno v:
Current HIV Research
Mononuclear phagocytes including monocytes and macrophages, are important defense components of innate immunity, but can be detrimental in HIV-1 infection by serving as the principal reservoirs of virus in brain and triggering a strong immune respons
Autor:
Richard J. Noel, Loyda M. Meléndez, Valerie Wojna, Gisela Delgado, Krystal Colon, Vanessa Rivera-Amill, Steven E Massey, Fabián J. Vázquez-Santiago
Objective: HIV-1 variants with different tropisms are associated with various neuropathologies. This study intends to determine if this correlation is determined by unique viral env sequences. We hypothesize that HIV-1 envelope gene sequence changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feeecfed23c3b35a6f44798a4b92c527
https://europepmc.org/articles/PMC4922650/
https://europepmc.org/articles/PMC4922650/