Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kruttika Bhat"'
Autor:
Ling He, Kruttika Bhat, Sara Duhacheck-Muggy, Angeliki Ioannidis, Le Zhang, Nhan T. Nguyen, Neda A. Moatamed, Frank Pajonk
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 2, Pp 197-209 (2021)
Pro-inflammatory conditions have long been associated with mammary carcinogenesis and breast cancer progression. The underlying mechanisms are incompletely understood but signaling of pro-inflammatory cytokine TNFα through its receptors TNFR1 and TN
Externí odkaz:
https://doaj.org/article/5f3b6de0ed604aa2bc4f1d4989e411f7
Autor:
Sara Duhachek‐Muggy, Kruttika Bhat, Paul Medina, Fei Cheng, Ling He, Claudia Alli, Mohammad Saki, Sree Deepthi Muthukrishnan, Gregoire Ruffenach, Mansoureh Eghbali, Erina Vlashi, Frank Pajonk
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 1, Pp 106-119 (2020)
Abstract The objective of the study was to identify the mechanism of action for a radiation mitigator of the gastrointestinal (GI) acute radiation syndrome (ARS), identified in an unbiased high‐throughput screen. We used mice irradiated with a leth
Externí odkaz:
https://doaj.org/article/91a88a70c1ea425785506c378e541c3e
Autor:
Kruttika Bhat, Kiri Sandler, Sara Duhachek-Muggy, Claudia Alli, Fei Cheng, Neda A. Moatamed, Clara E. Magyar, Lin Du, Gang Li, Susan McCloskey, Erina Vlashi, Frank Pajonk
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-13 (2019)
Abstract Background Cancer is frequently associated with tumor-related anemia, and many chemotherapeutic agents impair hematopoiesis, leading to impaired quality of life for affected patients. The use of erythropoiesis-stimulating agents has come und
Externí odkaz:
https://doaj.org/article/26477644472445e0bf7667812f5edb08
Autor:
Jaydutt V. Vadgama, Marianna Sarkissyan, Jesse Haro, Kruttika Bhat, Kevin T. Kemp, Yahya Elshimali, Mohammad Atefi, Sami Dwabe, Ke Wu, Xianghua Yi, Xiaoting Yu, Yong Wu
Figure S4 Quantification of Western blot analysis (related to Figure 4) (B-G). Data are presented as mean fold increases ({plus minus}SD) in treated groups over basal values from three independent experiments. B, *p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed3798d919d285c92e47b29be5927f4
https://doi.org/10.1158/0008-5472.22418025
https://doi.org/10.1158/0008-5472.22418025
Autor:
Jaydutt V. Vadgama, Marianna Sarkissyan, Jesse Haro, Kruttika Bhat, Kevin T. Kemp, Yahya Elshimali, Mohammad Atefi, Sami Dwabe, Ke Wu, Xianghua Yi, Xiaoting Yu, Yong Wu
Figure S6 The comparison of expression levels of phospho-ERK and phospho-Smad4 between lean and overweight/obesity patients, Related to Figure 7. Staining was analyzed by using a system based on the percentage of positively stained cells and the stai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568aa6ebd0f4172415f3f594e48cd70c
https://doi.org/10.1158/0008-5472.22418019.v1
https://doi.org/10.1158/0008-5472.22418019.v1
Autor:
Jaydutt V. Vadgama, Marianna Sarkissyan, Jesse Haro, Kruttika Bhat, Kevin T. Kemp, Yahya Elshimali, Mohammad Atefi, Sami Dwabe, Ke Wu, Xianghua Yi, Xiaoting Yu, Yong Wu
Obesity increases the risk of distant metastatic recurrence and reduces breast cancer survival. However, the mechanisms behind this pathology and identification of relevant therapeutic targets are poorly defined. Plasma free fatty acids (FFA) levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8fa1b7be342e6abc5cc529b56044ae
https://doi.org/10.1158/0008-5472.c.6510009
https://doi.org/10.1158/0008-5472.c.6510009
Autor:
Jaydutt V. Vadgama, Marianna Sarkissyan, Jesse Haro, Kruttika Bhat, Kevin T. Kemp, Yahya Elshimali, Mohammad Atefi, Sami Dwabe, Ke Wu, Xianghua Yi, Xiaoting Yu, Yong Wu
Figure S1 Quantification of Western blot analysis (related to Figure 1) (A-H). Data are presented as mean fold increases ({plus minus}SD) in treated groups over basal values from three independent experiments. *p < 0.01 versus controls; #p < 0.01 ver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60890bac84cec12a508e8923225c349f
https://doi.org/10.1158/0008-5472.22418034
https://doi.org/10.1158/0008-5472.22418034
Autor:
Jaydutt V. Vadgama, Marianna Sarkissyan, Jesse Haro, Kruttika Bhat, Kevin T. Kemp, Yahya Elshimali, Mohammad Atefi, Sami Dwabe, Ke Wu, Xianghua Yi, Xiaoting Yu, Yong Wu
Figure S3 FFA promotes TGF-beta-induced migration by activating ERK and USP9x, Related to Figure 3. A, BT549 cells were plated in Ibidi culture insert dishes (Madison, WI). Cells were cultured in complete medium to 80% confluence, inserts were remove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70be841a3dfa0f26dbf9bc1ac84bf1ac
https://doi.org/10.1158/0008-5472.22418028.v1
https://doi.org/10.1158/0008-5472.22418028.v1
Publikováno v:
bioRxiv
BackgroundDopamine receptor antagonists are psychotropic drugs that have been originally developed against psychiatric disorders. We recently identified dopamine receptor antagonists as potential anti-cancer agents and some have entered clinical tria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3693e09f1948eba9632e1201058c07e4
https://doi.org/10.1101/2023.01.18.524632
https://doi.org/10.1101/2023.01.18.524632
Autor:
Kruttika Bhat, Le Zhang, Ling He, Neda A. Moatamed, Sara Duhacheck-Muggy, Angeliki Ioannidis, Nhan T. Nguyen, Frank Pajonk
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 2, Pp 197-209 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 2, Pp 197-209 (2021)
Pro-inflammatory conditions have long been associated with mammary carcinogenesis and breast cancer progression. The underlying mechanisms are incompletely understood but signaling of pro-inflammatory cytokine TNFα through its receptors TNFR1 and TN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af59416ef11a1902b82c9c1a083c8797
https://doi.org/10.1016/j.neo.2020.12.007
https://doi.org/10.1016/j.neo.2020.12.007