Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kruthika Iyer"'
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Arenaviruses belonging to the Arenaviridae family, genus mammarenavirus, are enveloped, single-stranded RNA viruses primarily found in rodent species, that cause severe hemorrhagic fever in humans. With high mortality rates and limited treatment opti
Externí odkaz:
https://doaj.org/article/09b11ff05ea54225800fdda10b105462
Autor:
Ali R. Keramati, Ming-Huei Chen, Benjamin A. T. Rodriguez, Lisa R. Yanek, Arunoday Bhan, Brady J. Gaynor, Kathleen Ryan, Jennifer A. Brody, Xue Zhong, Qiang Wei, NHLBI Trans-Omics for Precision (TOPMed) Consortium, Kai Kammers, Kanika Kanchan, Kruthika Iyer, Madeline H. Kowalski, Achilleas N. Pitsillides, L. Adrienne Cupples, Bingshan Li, Thorsten M. Schlaeger, Alan R. Shuldiner, Jeffrey R. O’Connell, Ingo Ruczinski, Braxton D. Mitchell, Nauder Faraday, Margaret A. Taub, Lewis C. Becker, Joshua P. Lewis, Rasika A. Mathias, Andrew D. Johnson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Platelet aggregation is associated with myocardial infarction and stroke. Here, the authors have conducted a whole genome sequencing association study on platelet aggregation, discovering a locus in RGS18, where enhancer assays suggest an effect on a
Externí odkaz:
https://doaj.org/article/21f176ab19b541d294b9acdf21deb0ae
Autor:
Ali R Keramati, Lisa R Yanek, Kruthika Iyer, Margaret A Taub, Ingo Ruczinski, Diane M Becker, Lewis C Becker, Nauder Faraday, Rasika A Mathias
Publikováno v:
Platelets, Vol 30, Iss 3, Pp 380-386 (2019)
Coronary artery disease (CAD) remains a major cause of mortality and morbidity worldwide. The aggregation of activated platelets on a ruptured atherosclerotic plaque is a critical step in most acute cardiovascular events like myocardial infarction. P
Externí odkaz:
https://doaj.org/article/b790f074c0ea435882fe302444b47ceb
Autor:
Kanika Kanchan, Kruthika Iyer, Lisa R Yanek, Ivan Carcamo-Orive, Margaret A Taub, Claire Malley, Kristin Baldwin, Lewis C Becker, Ulrich Broeckel, Linzhao Cheng, Chad Cowan, Matteo D'Antonio, Kelly A Frazer, Thomas Quertermous, Gustavo Mostoslavsky, George Murphy, Marlene Rabinovitch, Daniel J Rader, Martin H Steinberg, Eric Topol, Wenli Yang, Joshua W Knowles, Cashell E Jaquish, Ingo Ruczinski, Rasika A Mathias
Publikováno v:
Stem Cell Research, Vol 46, Iss , Pp 101803- (2020)
Human induced pluripotent stem cell (hiPSC) lines have previously been generated through the NHLBI sponsored NextGen program at nine individual study sites. Here, we examined the structural integrity of 506 hiPSC lines as determined by copy number va
Externí odkaz:
https://doaj.org/article/67a1f93cf892404e97877984f372295c
Publikováno v:
Cell Stress & Chaperones
Heat shock proteins (HSPs) are a group of cellular proteins that are induced during stress conditions such as heat stress, cold shock, UV irradiation and even pathogenic insult. They are classified into families based on molecular size like HSP27, 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b720b4481d85064ec3cd14b8988d37e7
https://doi.org/10.1007/s12192-021-01223-3
https://doi.org/10.1007/s12192-021-01223-3
Publikováno v:
Virus research.
The Human Immunodeficiency Virus-1 (HIV-1) is known to modulate the host environment for successful replication and propagation like other viruses. The virus utilises its proteins to interact with or modulate host factors and host signalling pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41eb1b6831a71feb5544f5394fb8e54e
https://pubmed.ncbi.nlm.nih.gov/36581045
https://pubmed.ncbi.nlm.nih.gov/36581045
Publikováno v:
Cell Stress Chaperones
Heat shock proteins (HSPs) are a family of cellular proteins involved in a variety of biological functions including chaperone activity. HSPs are classified based on their molecular weight and each family has several isoforms in eukaryotes. HSP40 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7427338fa5f0b80866a4c52c52fe8bac
https://doi.org/10.1007/s12192-020-01185-y
https://doi.org/10.1007/s12192-020-01185-y
Autor:
Rasika Mathias, Kruthika Iyer, Margaret Taub, Lisa Yanek, Diane Becker, Lewis Becker, Dhananjay Vaidya
Publikováno v:
Circulation. 132
Background: Shorter telomere length is associated with an increased risk of coronary artery disease (CAD). A prior genomewide association study (GWAS) on 37,684 European ancestry individuals identified seven loci determining leukocyte telomere length
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49ca4d18c595143dc62fca23bf9fe117
https://doi.org/10.1161/circ.132.suppl_3.16819
https://doi.org/10.1161/circ.132.suppl_3.16819