Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Krushna, Sonar"'
Autor:
Yuval Gurfinkel, Nicole Polain, Krushna Sonar, Penelope Nice, Ricardo L. Mancera, Sarah Lyn Rea
Publikováno v:
Neurobiology of Disease, Vol 174, Iss , Pp 105859- (2022)
Mutations in the Tank-binding kinase 1 (TBK1) gene were identified in 2015 in individuals with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). They account for ∼3–4% of cases. To date, over 100 distinct mutations
Externí odkaz:
https://doaj.org/article/224b6571ec0e4e29976a4da442979b09
Autor:
Krushna Sonar, Ricardo L. Mancera
Publikováno v:
The Journal of Physical Chemistry B. 126:7916-7933
Intrinsically disordered peptides, such as amyloid β42 (Aβ42), lack a well-defined structure in solution. Aβ42 can undergo abnormal aggregation and amyloidogenesis in the brain, forming fibrillar plaques, a hallmark of Alzheimer's disease. The ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308cca6f99f8fecdca8810b4564e850a
https://doi.org/10.1021/acs.jpcb.2c04743
https://doi.org/10.1021/acs.jpcb.2c04743
Publikováno v:
Molecules, Vol 23, Iss 9, p 2142 (2018)
Human islet amyloid polypeptide (hIAPP) is a naturally occurring, intrinsically disordered protein whose abnormal aggregation into amyloid fibrils is a pathological feature in type 2 diabetes, and its cross-aggregation with amyloid beta has been link
Externí odkaz:
https://doaj.org/article/880d0fc357b34ebfa8c864bdc8e72e49
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics. 1869(4)
The β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8362301cc2a0a0cfe898bd333869f0bf
https://pubmed.ncbi.nlm.nih.gov/33453412
https://pubmed.ncbi.nlm.nih.gov/33453412
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-6 (2018)
Scientific Reports
Scientific Reports
TryTransDB is a web-based resource that stores transport protein data which can be retrieved using a standalone BLAST tool. We have attempted to create an integrated database that can be a one-stop shop for the researchers working with transport prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6951d8e7e9bfa95de78e8a58722cb65d
http://link.springer.com/article/10.1038/s41598-018-22706-x
http://link.springer.com/article/10.1038/s41598-018-22706-x
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1869:140605
The β2-adrenergic receptor (β2AR) is a member of the G protein-coupled receptor (GPCR) family that is an important drug target for asthma and COPD. Clinical studies coupled with biochemical data have identified a critical receptor variant, Thr164Il
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a491cff23ce0b508fc7d99fa314465b4
https://doi.org/10.1016/j.bbapap.2021.140605
https://doi.org/10.1016/j.bbapap.2021.140605
Publikováno v:
Molecules, Vol 23, Iss 9, p 2142 (2018)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
© 2018 by the authors. Human islet amyloid polypeptide (hIAPP) is a naturally occurring, intrinsically disordered protein whose abnormal aggregation into amyloid fibrils is a pathological feature in type 2 diabetes, and its cross-aggregation with am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6f8759c87fa92d2098cbc6f9eaa23d
http://www.mdpi.com/1420-3049/23/9/2142
http://www.mdpi.com/1420-3049/23/9/2142
Publikováno v:
Methods in cell biology. 142
G protein-coupled receptors (GPCRs) are an important class of drug targets owing to their physiological role. A large number of clinically relevant single nucleotide polymorphisms (SNPs) have been observed in GPCRs that are linked to disease suscepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::133a5535e18d97021f6de1aa372c70f3
https://pubmed.ncbi.nlm.nih.gov/28964336
https://pubmed.ncbi.nlm.nih.gov/28964336
G protein-coupled receptors (GPCRs) are an important class of drug targets owing to their physiological role. A large number of clinically relevant single nucleotide polymorphisms (SNPs) have been observed in GPCRs that are linked to disease suscepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f242375f9b516e6e0e281e46a894c98e
https://doi.org/10.1016/bs.mcb.2017.07.013
https://doi.org/10.1016/bs.mcb.2017.07.013
