Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Krunoslav Nujić"'
Autor:
Tatjana Kovačević, Krunoslav Nujić, Mario Cindrić, Snježana Dragojević, Adrijana Vinter, Amela Hozić, Milan Mesić
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
The process of identifying the protein targets and off-targets of a biologically active compound is of great importance in modern drug discovery. Various chemical proteomics approaches have been established for this purpose. To compare the different
Externí odkaz:
https://doaj.org/article/0e9e0eecf46f428088a5bbe0540be1c8
Autor:
Ivica Rubelj, Višnja Stepanić, Dubravko Jelić, Nikolina Škrobot Vidaček, Andrea Ćukušić Kalajžić, Milena Ivanković, Krunoslav Nujić, Mario Matijašić, Donatella Verbanac
Publikováno v:
Molecules, Vol 17, Iss 7, Pp 7864-7886 (2012)
In vitro high-throughput screening was carried out in order to detect new activities for old drugs and to select compounds for the drug development process comprising new indications. Tebrophen, a known antiviral drug, was found to inhibit activities
Externí odkaz:
https://doaj.org/article/5064bc1910c4431aa4ef396a57fc5716
Autor:
Darija Stupin Polančec, Krunoslav Nujić, Martina Bosnar, Ines Glojnarić, Nikola Marjanović, Miroslava Dominis-Kramarić, Vesna Eraković Haber
Publikováno v:
International Immunopharmacology. 15:498-504
Recent reports suggest that azithromycin can shift macrophage polarization towards the alternatively activated M2 phenotype. In order to investigate its immunomodulatory activity in vivo, the influence of azithromycin on survival and cytokine product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964ad5c41d448c41386666866e6c0490
https://doi.org/10.1016/j.intimp.2013.02.011
https://doi.org/10.1016/j.intimp.2013.02.011
Autor:
Jasna Padovan, Sulejman Alihodžić, Vesna Eraković Haber, Mario Matijašić, Krunoslav Nujić, Vesna Munic Kos, Snježana Čužić, Goran Kragol, Donatella Verbanac, Boris Mildner
Publikováno v:
Pharmacological Research. 66:332-342
Exceptional therapeutic effects of macrolides in treating various infections and inflammatory conditions can be significantly contributed to their unique pharmacokinetic properties. Macrolides accumulate in cells and tissues, with concentrations usua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38a97f4c24036f96a9e9e8dee21f976
https://doi.org/10.1016/j.phrs.2012.06.001
https://doi.org/10.1016/j.phrs.2012.06.001
Autor:
Vesna Munić, Mila Vrančić, D Stupin Polančec, Daniela Belamarić, V Eraković Haber, Krunoslav Nujić, Michael J. Parnham, Martina Bosnar, T Murati, Mihailo Banjanac
Publikováno v:
British Journal of Pharmacology. 165:1348-1360
BACKGROUND AND PURPOSE Azithromycin has been reported to modify activation of macrophages towards the M2 phenotype. Here, we have sought to identify the mechanisms underlying this modulatory effect of azithromycin on human monocytes, classically acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::483087ac23d543b8bcc29a9834414ac6
https://doi.org/10.1111/j.1476-5381.2011.01576.x
https://doi.org/10.1111/j.1476-5381.2011.01576.x
Publikováno v:
Cellular immunology. 279(1)
Azithromycin and chloroquine have been shown to exhibit anti-inflammatory activities in a number of cellular systems, but the mechanisms of these activities have still not been clarified unequivocally. Since both drugs are cationic, accumulate in aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82581e021aed412a0e4370e71402b3e0
https://pubmed.ncbi.nlm.nih.gov/23099154
https://pubmed.ncbi.nlm.nih.gov/23099154
Autor:
Mario Matijašić, Nikolina Škrobot Vidaček, Krunoslav Nujić, Milena Ivanković, Donatella Verbanac, Višnja Stepanić, Ivica Rubelj, Dubravko Jelić, Andrea Ćukušić Kalajžić
Publikováno v:
Molecules
Volume 17
Issue 7
Pages 7864-7886
Volume 17
Issue 7
Pages 7864-7886
In vitro high-throughput screening was carried out in order to detect new activities for old drugs and to select compounds for the drug development process comprising new indications. Tebrophen, a known antiviral drug, was found to inhibit activities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9183b7c086e1d49665c198b88f30c7a0
Autor:
Mario Hlevnjak, Krunoslav Nujić, Mihailo Banjanac, Daniela Belamarić, Vesna Munic Kos, Slaven Crnković, Vesna Eraković Haber, Mila Vrančić
Publikováno v:
Pharmacological research. 66(4)
Azithromycin is a macrolide antibiotic with well-described anti-inflammatory properties which can be attributed, at least partially, to its action on macrophages. We have previously shown, with 18 different macrolide molecules, that IL-6 and PGE₂ i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e508c2ec702f613971302ec85216c72
https://pubmed.ncbi.nlm.nih.gov/22766077
https://pubmed.ncbi.nlm.nih.gov/22766077
Autor:
Sulejman Alihodžić, Denis Polančec, Marjorie A. Smith, Ivica Malnar, Vesna Eraković Haber, Michael Lee, Krunoslav Nujić, Daniela Belamarić, Linda Tomaskovic, Klaus Schneider
Publikováno v:
European journal of pharmacology. 677(1-3)
In addition to antibacterial activity, some macrolide antibiotics, such as azithromycin and clarithromycin, also exhibit anti- inflammatory properties in vitro and in vivo, although the targets and mechanism(s) of action remain unknown. The aim of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f6d19774f35f9fd6b65e1599c16cd6
https://pubmed.ncbi.nlm.nih.gov/22209877
https://pubmed.ncbi.nlm.nih.gov/22209877
Dipeptidyl peptidase IV is a glycoprotein which removes N-terminal dipeptides from physiologically relevant polypeptides. An homologous series of 6-imino-2-thioxo-5-{; ; [3, 4, 5-tris(methyloxy)phenyl]methyl}; ; -2, 5-dihydro-4(3H)-pyrimidinones has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1de576f2ee36e472f4f203df63b150f
https://www.bib.irb.hr/474331
https://www.bib.irb.hr/474331
