Improved EGFR mutation detection using combined exosomal RNA and circulating tumor DNA in NSCLC patient plasma.

Autor: Krug AK; Exosome Diagnostics GmbH, Martinsried, Germany., Enderle D; Exosome Diagnostics GmbH, Martinsried, Germany., Karlovich C; Clovis Oncology Inc., San Francisco., Priewasser T; Exosome Diagnostics GmbH, Martinsried, Germany., Bentink S; Exosome Diagnostics GmbH, Martinsried, Germany., Spiel A; Exosome Diagnostics GmbH, Martinsried, Germany., Brinkmann K; Exosome Diagnostics GmbH, Martinsried, Germany., Emenegger J; Exosome Diagnostics GmbH, Martinsried, Germany., Grimm DG; Exosome Diagnostics GmbH, Martinsried, Germany., Castellanos-Rizaldos E; Exosome Diagnostics Inc, Waltham., Goldman JW; University of California Los Angeles, Los Angeles., Sequist LV; Massachusetts General Hospital, Boston, USA., Soria JC; Institut Gustave Roussy, Villejuif; University Paris-Sud, Paris, France., Camidge DR; University of Colorado, Denver., Gadgeel SM; Karmanos Cancer Institute, Detroit; Wayne State University, Detroit., Wakelee HA; Stanford University, Stanford, USA., Raponi M; Clovis Oncology Inc., San Francisco., Noerholm M; Exosome Diagnostics GmbH, Martinsried, Germany., Skog J; Exosome Diagnostics Inc, Waltham. Electronic address: johan@exosomedx.com.

Publikováno v: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2018 Mar 01; Vol. 29 (3), pp. 700-706.

Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+).

Autor: Krug AK; Doerenkamp-Zbinden Chair for In Vitro Toxicology and Biomedicine, University of Konstanz, Konstanz D-78457, Germany., Gutbier S; Doerenkamp-Zbinden Chair for In Vitro Toxicology and Biomedicine, University of Konstanz, Konstanz D-78457, Germany., Zhao L; Center for Alternatives to Animal Testing (CAAT-US), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA., Pöltl D; 1] Doerenkamp-Zbinden Chair for In Vitro Toxicology and Biomedicine, University of Konstanz, Konstanz D-78457, Germany [2] Konstanz Research School Chemical Biology, University of Konstanz, Konstanz, Germany., Kullmann C; Doerenkamp-Zbinden Chair for In Vitro Toxicology and Biomedicine, University of Konstanz, Konstanz D-78457, Germany., Ivanova V; 1] Konstanz Research School Chemical Biology, University of Konstanz, Konstanz, Germany [2] Nycomed Chair for Bioinformatics and Information Mining, University of Konstanz, Konstanz D-78457, Germany., Förster S; Doerenkamp-Zbinden Chair for In Vitro Toxicology and Biomedicine, University of Konstanz, Konstanz D-78457, Germany., Jagtap S; Center of Physiology and Pathophysiology, Institute of Neurophysiology, University of Cologne, Cologne D-50931, Germany., Meiser J; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Campus Belval, Esch-Belval L-4362, Luxembourg., Leparc G; Boehringer Ingelheim Pharma GmbH & Co. KG Div. Research, Ingelheim, Germany., Schildknecht S; Doerenkamp-Zbinden Chair for In Vitro Toxicology and Biomedicine, University of Konstanz, Konstanz D-78457, Germany., Adam M; Doerenkamp-Zbinden Chair for In Vitro Toxicology and Biomedicine, University of Konstanz, Konstanz D-78457, Germany., Hiller K; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Campus Belval, Esch-Belval L-4362, Luxembourg., Farhan H; Biotechnology Institute Thurgau at the University of Konstanz, Kreuzlingen CH-8280, Switzerland., Brunner T; Chair of Biochemical Pharmacology, University of Konstanz, Konstanz D-78457, Germany., Hartung T; Center for Alternatives to Animal Testing (CAAT-US), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA., Sachinidis A; Center of Physiology and Pathophysiology, Institute of Neurophysiology, University of Cologne, Cologne D-50931, Germany., Leist M; Doerenkamp-Zbinden Chair for In Vitro Toxicology and Biomedicine, University of Konstanz, Konstanz D-78457, Germany.

Publikováno v: Cell death & disease [Cell Death Dis] 2014 May 08; Vol. 5, pp. e1222. Date of Electronic Publication: 2014 May 08.

Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.

Autor: Krug AK; Department of Biology, University of Konstanz, 78457 Constance, Germany., Kolde R, Gaspar JA, Rempel E, Balmer NV, Meganathan K, Vojnits K, Baquié M, Waldmann T, Ensenat-Waser R, Jagtap S, Evans RM, Julien S, Peterson H, Zagoura D, Kadereit S, Gerhard D, Sotiriadou I, Heke M, Natarajan K, Henry M, Winkler J, Marchan R, Stoppini L, Bosgra S, Westerhout J, Verwei M, Vilo J, Kortenkamp A, Hescheler J, Hothorn L, Bremer S, van Thriel C, Krause KH, Hengstler JG, Rahnenführer J, Leist M, Sachinidis A

Publikováno v: Archives of toxicology [Arch Toxicol] 2013 Jan; Vol. 87 (1), pp. 123-43. Date of Electronic Publication: 2012 Nov 21.