On the validity of reference tissue models for analysing (R)-[11C]PK11195 studies in traumatic brain injury

Autor: Boellaard, Ronald, Folkersma, Hedy, Kropholler, Marc A., Luurtsema, Gert, Vandertop, W.Peter, Lammertsma, Adriaan A., Van Berckel, Bart N N

Publikováno v: Journal of Cerebral Blood Flow and Metabolism, 27(SUPPL. 1). Nature Publishing Group
Journal of cerebral blood flow and metabolism, 27(SUPPL. 1), PO02-04U. Nature Publishing Group
Boellaard, R, Folkersma, H, Kropholler, M A, Luurtsema, G, Vandertop, W P, Lammertsma, A A & Van Berckel, B N N 2007, ' On the validity of reference tissue models for analysing (R)-[11C]PK11195 studies in traumatic brain injury ', Journal of Cerebral Blood Flow and Metabolism, vol. 27, no. SUPPL. 1 .

Introduction: Activated microglia in the brain can be imaged in vivo using (R)-[11C]PK11195 and PET. In theory, this activation can be quantified using a reference tissue approach, provided that an appropriate reference tissue is available. The purpo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3b17f8f23d275a647e2688959a41f0c1
https://research.vumc.nl/en/publications/461fef30-e71a-47aa-848b-757b66748f5a

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Microglial activation in Alzheimer's disease: an (R)-[¹¹C]PK11195 positron emission tomography study

Autor: Schuitemaker, Alie^1,2 ASchuitemaker@zuwehofpoort.nl, Kropholler, Marc A.², Boellaard, Ronald², van der Flier, Wiesje M.^1,3, Kloet, Reina W.², van der Doef, Thalia F.^2,4, Knol, Dirk L.³, Windhorst, Albert D.², Luurtsema, Gert², Barkhof, Frederik⁵, Jonker, Cees¹, Lammertsma, Adriaan A.², Scheltens, Philip¹, van Berckel, Bart N.M.²

Publikováno v: Neurobiology of Aging. Jan2013, Vol. 34 Issue 1, p128-136. 9p.

Evaluation of methods for generating parametric (R)-[¹¹C]PK11195 binding images.

Autor: Schuitemaker, Alie, Van Berckel, Bart N. M., Kropholler, Marc A., Kloet, Reina W., Jonker, Cees, Scheltens, Philip, Lammertsma, Adriaan A., Boellaard, Ronald

Publikováno v: Journal of Cerebral Blood Flow & Metabolism; Sep2007, Vol. 27 Issue 9, p1603-1615, 13p, 1 Black and White Photograph, 4 Charts, 5 Graphs