Can we S ave the rectum by watchful waiting or T rans A nal microsurgery following (chemo) R adiotherapy versus T otal mesorectal excision for early RE ctal C ancer (STAR-TREC study)?: protocol for a multicentre, randomised feasibility study.

Autor: Rombouts AJM; Department of Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands., Al-Najami I; Department of Surgery, Odense University Hospital, Odense, Denmark., Abbott NL; Radiotheraphy Trials Quality Assurance Group, Velindre Cancer Centre, Cardiff, UK., Appelt A; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.; Leeds Cancer Centre, St. James' University Hospital, Leeds, UK., Baatrup G; Department of Surgery, Odense University Hospital, Odense, Denmark., Bach S; Department of Surgery, University Hospitals Birmingham, Birmingham, UK., Bhangu A; Department of Surgery, University Hospitals Birmingham, Birmingham, UK., Garm Spindler KL; Department of Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Gray R; Clinical Trial Services Unit, University of Oxford, Oxford, UK., Handley K; Institue of Applied Health Research, University of Birmingham Clinical Trials Unit, Birmingham, UK., Kaur M; Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK., Kerkhof E; Department of Radiotherapy, Leiden University Medical Center, Leiden, The Netherlands., Kronborg CJ; Department of Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark., Magill L; Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK., Marijnen CAM; Department of Radiotherapy, Leiden University Medical Center, Leiden, The Netherlands., Nagtegaal ID; Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands., Nyvang L; Department of Medical Physics, Aarhus University Hospital, Aarhus, Denmark., Peters FP; Department of Radiotherapy, Leiden University Medical Center, Leiden, The Netherlands., Pfeiffer P; Department of Oncology, Odense University Hospital, Odense, Denmark., Punt C; Department of Medical Oncology, Academic Medical Center, Amsterdam, The Netherlands., Quirke P; Department of Pathology, School of Medicine, University of Leeds, Leeds, UK., Sebag-Montefiore D; Department of Clinical Oncology, Leeds Radiotherapy Research Group, University of Leeds, Leeds, UK., Teo M; Department of Clinical Oncology, Leeds Radiotherapy Research Group, University of Leeds, Leeds, UK.; Department of Clinical Oncology, Leeds Cancer Centre, St James University Hospital, Leeds, UK., West N; Department of Pathology, School of Medicine, University of Leeds, Leeds, UK., de Wilt JHW; Department of Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands.

Publikováno v: BMJ open [BMJ Open] 2017 Dec 28; Vol. 7 (12), pp. e019474. Date of Electronic Publication: 2017 Dec 28.