Naturally circulating pertactin-deficient strains induce distinct gene expression and inflammatory signatures in human dendritic cells

Autor: Kroes, Michiel M, Miranda-Bedate, Alberto, Hovingh, Elise S, Jacobi, Ronald, Schot, Corrie, Pupo, Elder, Raeven, René H M, van der Ark, Arno A J, van Putten, Jos P M, de Wit, Jelle, Mariman, Rob, Pinelli, Elena

Respiratory infections caused by Bordetella pertussis are reemerging despite high pertussis vaccination coverage. Since the introduction of the acellular pertussis vaccine in the late twentieth century, circulating B. pertussis strains increasingly l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::801a3d4b32a98965ade5f35ad6c156d0
http://hdl.handle.net/10029/625065

Activation of Human NK Cells by Requires Inflammasome Activation in Macrophages

Autor: Kroes, Michiel M, Mariman, Rob, Hijdra, Daniëlle, Hamstra, Hendrik-Jan, van Boxtel, Karlijn J W M, van Putten, Jos P M, de Wit, Jelle, Pinelli, Elena

Pertussis is a highly contagious respiratory infection caused by the bacterium Bordetella pertussis. Humans are the only known natural reservoir of B. pertussis. In mice, macrophages and NK cells have a key role in confining B. pertussis to the respi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::35fe7795a7248bcf76b297c244a8722f
http://hdl.handle.net/10029/623278

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Naturally circulating pertactin-deficient Bordetella pertussis strains induce distinct gene expression and inflammatory signatures in human dendritic cells.

Autor: Kroes MM; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.; Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands., Miranda-Bedate A; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands., Hovingh ES; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands., Jacobi R; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands., Schot C; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands., Pupo E; Institute for Translational Vaccinology (Intravacc), Bilthoven, Netherlands., Raeven RHM; Institute for Translational Vaccinology (Intravacc), Bilthoven, Netherlands., van der Ark AAJ; Institute for Translational Vaccinology (Intravacc), Bilthoven, Netherlands., van Putten JPM; Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands., de Wit J; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands., Mariman R; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands., Pinelli E; Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.

Publikováno v: Emerging microbes & infections [Emerg Microbes Infect] 2021 Dec; Vol. 10 (1), pp. 1358-1368.