The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo

Autor: Dennis James W, Krizus Aldis, Johnston Wendy L

Publikováno v: BMC Biology, Vol 4, Iss 1, p 35 (2006)

Abstract Background Fertilization restores the diploid state and begins the process by which the single-cell oocyte is converted into a polarized, multicellular organism. In the nematode, Caenorhabditis elegans, two of the earliest events following f

Externí odkaz: https://doaj.org/article/2caf8a076ca54b06b68f74cdb9d21d1a

Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans

Autor: Suneil K. Kalia, Omar M. A. El-Agnaf, Jarlath Byrne Rodgers, Aldis Krizus, Minesh Kapadia, Darren M O'Hara, Kazuko Fujisawa, Lorraine V. Kalia, Krystal Menezes, Joseph G. Culotti, Kevin S Chen, William S. Ryu, Susan Ping, Naomi P. Visanji, Hien Chau, Grishma Pawar, Satoshi Suo, Nour K. Majbour, Seiya Ishikura, Andres M. Lozano, Scott Spangler, Nhat Tran, Anna Cranston, Alix M. B. Lacoste, Shahin Khodaei, Connie Marras

Publikováno v: Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-25 (2021)

Background Parkinson’s disease is a disabling neurodegenerative movement disorder characterized by dopaminergic neuron loss induced by α-synuclein oligomers. There is an urgent need for disease-modifying therapies for Parkinson’s disease, but dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87a11cbb70df9392264f3dcb3df5afd
https://doi.org/10.1186/s13024-021-00497-6

Ship Noise Level Analysis Based on the International Regulations

Autor: Arnis Krizus, Rauls Klaucans, Deniss Kreisberg

Publikováno v: Transport and Aerospace Engineering; Vol 7, No 1 (2019): Transport and Aerospace Engineering; 41-48
Transport and Aerospace Engineering, Vol 7, Iss 1, Pp 41-48 (2019)

The target of analyse was to determine the exposure levels to the staff on the vessel and ensure adequate measures are in place to minimize the exposure when necessary. Noise levels through the vessel will be compared to the noise code detailed in se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ce9b0e3d2d8119f339f452ef35670d
https://doi.org/10.2478/tae-2019-0005

C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility.

Autor: Johnston, Wendy L.¹, Krizus, Aldis¹, Ramani, Arun K.², Dunham, Wade¹, Ji Young Youn¹, Fraser, Andrew G.^3,4, Gingras, Anne-Claude^1,3, Dennis, James W.^1,3 dennis@lunenfeld.ca

Publikováno v: BMC Biology. 7/17/2017, Vol. 15, p1-19. 19p.

Additional file 6: of C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility

Autor: Johnston, Wendy, Krizus, Aldis, Ramani, Arun, Dunham, Wade, Youn, Ji, Fraser, Andrew, Anne-Claude Gingras, Dennis, James

SUP-46 and GNA-1. (A) GNA-1 protein is increased in sup-46 mutants. Images show examples of gna-1::gfp-tagged wildtype and sup-46 mutants, with the gonad region used to quantify GNA-1::GFP traced by the white line. The graph on the right provides qua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291fe3c008489f00229c7e6cdb5580fb