Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kritika Mohan"'
Publikováno v:
Journal of PEARLDENT. 13:39-44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db517379877eeb1f631096f7e4458c68
https://doi.org/10.5958/2229-4457.2022.00005.8
https://doi.org/10.5958/2229-4457.2022.00005.8
Autor:
Nam-Chul Ha, Andrew C.T. Ha, Calvin J. Kuo, Y. Miao, Kanako Yuki, K. Park, David Baker, Claudia Y. Janda, Kenan Christopher Garcia, Jenny Yuan, Mario Vallon, Kritika Mohan, Kevin Jude, J.G. Vilches-Moure, Luke T. Dang
Publikováno v:
Nature structural & molecular biology
To discriminate between closely related members of a protein family that differ at a limited number of spatially distant positions is a challenge for drug discovery. We describe a combined computational design and experimental selection approach for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20c8c58bfe788473b42a6fcc3f63a65
http://europepmc.org/articles/PMC6582999
http://europepmc.org/articles/PMC6582999
Autor:
Leon Su, Robert A. Saxton, Nanda G. Aduri, Cornelius Gati, Kritika Mohan, Lukas T. Henneberg, K. Christopher Garcia, Gita C. Abhiraman, Naotaka Tsutsumi
Publikováno v:
Science
Cryo-EM helps engineer enhanced IL-10 Interleukin-10 (IL-10) binds to the IL-10 receptor (IL-10R), comprising two high-affinity α chains and two low-affinity β chains. Depending on the cellular context of its recognition, IL-10 can either suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfc01fc78ebd5e2db358ad9546ed5da
https://pubmed.ncbi.nlm.nih.gov/33737461
https://pubmed.ncbi.nlm.nih.gov/33737461
Autor:
Maximillian Hafer, Y. Miao, Yu Guo, Kritika Mohan, Kevin Jude, Jorge A. Fallas, Ah Ram Kim, Robert A. Saxton, Jacob Piehler, Kenan Christopher Garcia, Vijay G. Sankaran, Darren P. Baker, George Ueda
Publikováno v:
Science
INTRODUCTION: Receptor dimerization is a fundamental mechanism by which most cytokines and growth factors activate Type-I transmembrane receptors. Although previous studies have shown that ligand-induced topological changes in the extracellular domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a66c8ef6fd3e310bfef011753c071a5
https://doi.org/10.1126/science.aav7532
https://doi.org/10.1126/science.aav7532
Autor:
Gregory A. Weiss, Kritika Mohan
Publikováno v:
ACS chemical biology, vol 11, iss 5
Mohan, K; & Weiss, GA. (2016). Chemically Modifying Viruses for Diverse Applications. ACS CHEMICAL BIOLOGY, 11(5), 1167-1179. doi: 10.1021/acschembio.6b00060. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/94v7n80n
Mohan, K; & Weiss, GA. (2016). Chemically Modifying Viruses for Diverse Applications. ACS CHEMICAL BIOLOGY, 11(5), 1167-1179. doi: 10.1021/acschembio.6b00060. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/94v7n80n
Long fascinating to biologists, viruses offer nanometer-scale benchtops for building molecular-scale devices and materials. Viruses tolerate a wide-range of chemical modifications including reaction conditions, pH values, and temperatures. Recent exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3b16f73cc01f3d392c533851ea7e21
https://escholarship.org/uc/item/94v7n80n
https://escholarship.org/uc/item/94v7n80n
Publikováno v:
Mohan, K; Penner, RM; & Weiss, GA. (2015). Biosensing with Virus Electrode Hybrids.. Current protocols in chemical biology, 7(2), 53-72. doi: 10.1002/9780470559277.ch140213. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8gh2q9dr
Current Protocols in Chemical Biology
Current Protocols in Chemical Biology
Virus electrodes address two major challenges associated with biosensing. First, the surface of the viruses can be readily tailored for specific, high affinity binding to targeted biomarkers. Second, the viruses are entrapped in a conducting polymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b6ad14b9cd5946034851604bf987d2
http://www.escholarship.org/uc/item/8gh2q9dr
http://www.escholarship.org/uc/item/8gh2q9dr
Autor:
Gregory A. Weiss, Kritika Mohan
Publikováno v:
Mohan, K; & Weiss, GA. (2015). Engineering chemically modified viruses for prostate cancer cell recognition. Molecular BioSystems, 11(12), 3264-3272. doi: 10.1039/c5mb00511f. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1ts9x8t6
© The Royal Society of Chemistry 2015. Specific detection of circulating tumor cells and characterization of their aggressiveness could improve cancer diagnostics and treatment. Metastasis results from such tumor cells, and causes the majority of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a281da433be5f4f42a36d846c15650f2
http://www.escholarship.org/uc/item/1ts9x8t6
http://www.escholarship.org/uc/item/1ts9x8t6
Autor:
Gregory A. Weiss, Kritika Mohan
Publikováno v:
Mohan, K; & Weiss, GA. (2014). Dual genetically encoded phage-displayed ligands. Analytical Biochemistry, 453(1), 1-3. doi: 10.1016/j.ab.2014.02.025. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1507g8ps
M13 bacteriophage display presents polypeptides as fusions to phage coat proteins. Such phage-displayed ligands offer useful reagents for biosensors. Here, we report a modified phage propagation protocol for the consistent and robust display of two d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1bf3581e33717850dc1fc8cb4876eda
http://www.escholarship.org/uc/item/1507g8ps
http://www.escholarship.org/uc/item/1507g8ps
Publikováno v:
Journal of the American Chemical Society. 135(20)
The sensitive detection of cancer biomarkers in urine could revolutionize cancer diagnosis and treatment. Such detectors must be inexpensive, easy to interpret, and sensitive. This report describes a bioaffinity matrix of viruses integrated into PEDO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9267cb61328f5a91037491dd22098b
https://pubmed.ncbi.nlm.nih.gov/23614709
https://pubmed.ncbi.nlm.nih.gov/23614709