Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Krisztina Moricz"'
Autor:
Klára Szentmihályi, Szilvia Klébert, Krisztina Móricz, Antal Balázs Szenes-Nagy, Zoltán May, Eszter Bódis, Miklós Mohai, László Trif, Mirella Mirankó, Tivadar Feczkó, Zoltán Károly
Publikováno v:
Applied Sciences, Vol 14, Iss 20, p 9605 (2024)
Levocetirizine dihydrochloride is an effective antiallergenic drug applied mostly orally; however, developing a topical formulation for localized treatment could be beneficial. To achieve this, a modified formulation technique is necessary to enhance
Externí odkaz:
https://doaj.org/article/a8b4a9558459434c8cc8439afa2a2674
Autor:
Gabor Gigler, Patricia Machado, Istvan Gacsalyi, Ferenc A. Antoni, Katalin Megyeri, Krisztina Moricz
Publikováno v:
European Journal of Pharmacology. 834:118-125
This study examined the potential of the selective extra-synaptic α5-GABAA receptor inhibitor S44819 (Egis-13529) to improve cognitive performance in preclinical models of vascular cognitive impairment (VCI). Chronic hypoperfusion of the brain in mi
Autor:
Ferenc A. Antoni, Szabolcs Udvari, Katalin Megyeri, Ágnes Pataki, Istvan Gacsalyi, Balázs Mihalik, Krisztina Moricz, Gabor Gigler, Adrienn Pálvölgyi
Publikováno v:
Neuropharmacology. 128:408-415
Gamma-amino butyric acid (GABA) is an abundant neurotransmitter in the CNS. GABAergic interneurons orchestrate pyramidal neurons in the cerebral cortex, and thus control learning and memory. Ionotropic receptors for GABA (GABAAR) are heteropentameric
Autor:
Janos Wellmann, István Ling, Jeremy J. Lambert, Ferenc A. Antoni, József Haller, Krisztina Moricz, József Barkóczy, Katalin Nagy, Gábor Szénási, Gabor Gigler, Istvan Gacsalyi, Michael Spedding
Publikováno v:
Neuropharmacology. 125:30-38
Previous work has shown that S44819 is a novel GABAA receptor (GABAAR) antagonist, which is selective for extrasynaptic GABAARs incorporating the α5 subunit (α5-GABAARs). The present study reports on the preclinical neuropsychopharmacological profi
Autor:
Gábor Szénási, Anikó Kovács, Laszlo G. Harsing, Krisztina Moricz, Mihály Albert, Angéla Benedek
Publikováno v:
European Journal of Pharmacology. 644:154-159
The effects of brain ischemia and reperfusion on smooth muscle function in remote cerebral and peripheral arteries are hardly known. Maximum vasoconstrictions (Emax) caused by 120 mmol/l KCl and 5-HT in endothelium-denuded ring preparations were meas
Autor:
Gabor Gigler, Miklos Vegh, Szabolcs Kertesz, József Barkóczy, Annamária Simó, Angéla Benedek, Márta Ágoston, Geza Szabo, Marko Bernadett Martonne, Gábor Szénási, Istvan Gacsalyi, Gábor Kapus, Éva Matucz, Laszlo G. Harsing, György Lévay, Krisztina Moricz, Mihály Albert
Publikováno v:
British Journal of Pharmacology. 152:151-160
Background and purpose: Blockade of AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors is a good treatment option for a variety of central nervous system disorders. The present study evaluated the neuroprotective and anticonvulsan
Publikováno v:
Brain Research Bulletin. 46:519-528
The aim of this work was to study the effects of benzalkonium chloride (BAC) treatment on the small intestine and its functioning in rats surgically prepared with Thiry-Vella intestinal loop. The loops were treated with either BAC, which ablated much
Autor:
József Haller, Szabolcs Kertesz, Laszlo G. Harsing, Ferenc A. Antoni, Gábor Szénási, József Barkóczy, Judit Bíró, Istvan Gacsalyi, Krisztina Moricz, Gabor Gigler, György Lévay, Katalin Pallagi, Péter Varga, Katalin Nagy, Michael Spedding
Publikováno v:
Neuropharmacology. 64
Classical antipsychotics, e.g. haloperidol, chlorpromazine, are potent at controlling the positive symptoms of schizophrenia but frequently elicit extrapyramidal motor side-effects. The introduction of atypical antipsychotics such as risperidone, ola
Autor:
Éva Matucz, Krisztina Moricz, Gábor Szénási, József Barkóczy, Angéla Benedek, György Lévay, Laszlo G. Harsing, Gabor Gigler
Publikováno v:
Brain research. 1123(1)
EGIS-8332 and GYKI 53405 are selective, non-competitive AMPA (2-amino-3[3-hydroxy-5-methyl-4-isoxazolyl] propionic acid) antagonists that effectively protected against tissue injury caused by global and focal cerebral ischemia in laboratory animals.
Autor:
Gábor Szénási, Péter Mátyus, Laszlo G. Harsing, Gabor Gigler, Angéla Benedek, Mihály Albert, Zsolt Juranyi, György Lévay, Krisztina Moricz
Publikováno v:
Brain research. 1116(1)
2,3,5-Triphenyltetrazolium chloride (TTC) staining measures tissue viability used to evaluate infarct size. The goal of this study was to compare viability of neuronal tissue during the early phases of ischemia-reperfusion assessed either by perfusio