Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Krisztina Mekli"'
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background The immune response to infections could be largely driven by the individual’s genes, especially in the major histocompatibility complex (MHC) region. Varicella-zoster virus (VZV) is a highly communicable pathogen. In addition to
Externí odkaz:
https://doaj.org/article/6b476f9c17204f02a3bfc4e521be6ed6
Autor:
Krisztina Mekli, Artitaya Lophatananon, Rachel Cant, Alistair Burns, Curtis B. Dobson, Ruth F. Itzhaki, Kenneth R. Muir
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
The causes that trigger the onset of dementia are still unknown. Recently there has been an increasing interest in the possible role of infectious agents in the brain in the pathogenesis of this condition. Amongst the viruses, members of the Herpesvi
Externí odkaz:
https://doaj.org/article/dfc1f8623b164551895b8f9e67ed3d06
Autor:
Nicholas J. W. Rattray, Drupad K. Trivedi, Yun Xu, Tarani Chandola, Caroline H. Johnson, Alan D. Marshall, Krisztina Mekli, Zahra Rattray, Gindo Tampubolon, Bram Vanhoutte, Iain R. White, Frederick C. W. Wu, Neil Pendleton, James Nazroo, Royston Goodacre
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Risk of age-related chronic disorders and decrease in resilience is associated with ageing. Here the authors analyse the human blood metabolome and identify metabolites associated with frailty.
Externí odkaz:
https://doaj.org/article/f8a8be46f83b45fc975dd3c54a72ffd7
Autor:
Artitaya Lophatananon, Kenneth Muir, Rachel Cant, Krisztina Mekli, Curtis Dobson, Ruth Itzhaki
Publikováno v:
BMJ Open, Vol 11, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/b4430a0f2d414372bd14261d19047264
Autor:
Krisztina Mekli, Adam Stevens, Alan D Marshall, Thalida E Arpawong, Drystan F Phillips, Gindo Tampubolon, Jinkook Lee, Carol A Prescott, James Y Nazroo, Neil Pendleton
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207824 (2018)
The concept of frailty has been used in the clinical and research field for more than two decades. It is usually described as a clinical state of heightened vulnerability to poor resolution of homeostasis after a stressor event, which thereby increas
Externí odkaz:
https://doaj.org/article/bb1dd059987f4b4883c9fe164803fad2
Autor:
Thalida E Arpawong, Neil Pendleton, Krisztina Mekli, John J McArdle, Margaret Gatz, Chris Armoskus, James A Knowles, Carol A Prescott
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182448 (2017)
Verbal memory is typically studied using immediate recall (IR) and delayed recall (DR) scores, although DR is dependent on IR capability. Separating these components may be useful for deciphering the genetic variation in age-related memory abilities.
Externí odkaz:
https://doaj.org/article/357bc7457afc436da6be016febdc04fb
Autor:
Cemsel Bafligil, Deborah J. Thompson, Artitaya Lophatananon, Neil A.J. Ryan, Miriam J. Smith, Joe Dennis, Krisztina Mekli, Tracy A. O’Mara, D. Gareth Evans, Emma J. Crosbie
Publikováno v:
Genetics in Medicine. 24:1847-1856
Single-nucleotide variations (SNVs) (formerly single-nucleotide polymorphism [SNV]) influence genetic predisposition to endometrial cancer. We hypothesized that a polygenic risk score (PRS) comprising multiple SNVs may improve endometrial cancer risk
Background The immune response to infections could be largely driven by the individuals genes, especially in the major histocompatibility complex (MHC) region. Varicella-zoster virus (VZV) is a highly communicable pathogen. In addition to infection,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d595cb00c5d7341a84cb99ea78d3605
https://doi.org/10.1101/2022.07.29.22278202
https://doi.org/10.1101/2022.07.29.22278202
Autor:
Drystan Phillips, Carol A. Prescott, Jinkook Lee, Thalida Em Arpawong, Krisztina Mekli, Margaret Gatz
Publikováno v:
Aging Ment Health
We evaluated whether the effects of recent stressful life events (SLEs) and early childhood adversities (ECAs) on depressive symptoms are consistent between men and women and across older age, and whether there was evidence for: stress sensitization,
Autor:
Ainhoa Azqueta, Miriam Cabrita, Calogero Casa, Andrea Damiani, Sakis Dalianis, Krasimir Filipov, Giorgos Giotis, Lars Gustaffson, Pavlos Kranas, Dimosthenis Kyriazis, Rostislav Kostadinov, Artitaya Lophatananon, Chris Orton, Borja Liobell Crespo, George Marinos, George Manias, Shwetambara Malwade, Nikolay Mehandjiev, Krisztina Mekli, Kenneth Muir, Anna Nanou, Petia Nikolova, Marzena Nieroda, Harm Op den Akker, Anastasios Pantazidis, Aristodemos Pnevmatikakis, Usman Rashid, Shabbir Syed-Abdul, Tanja Tomson, Usman Wajid, Nerea Aguado Lopez, Eshita Dhar, Te-Min Ke
This deliverable summarizes the work that has been done in the score of Task 2.1 (“State of the art and requirement analysis”) until M12. This is the second version of a series of deliverables of this task, whose main objective is to specify the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720f39ab5c9b67f9d55668863a3a2fa3