Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Krisztina Hegedűs"'
Autor:
Laszlo Ducza, Andrea Gajtko, Krisztina Hegedűs, Erzsébet Bakk, Botond Gaál, Roland Takács, Péter Szücs, Krisztina Holló
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S678-S679 (2023)
Externí odkaz:
https://doaj.org/article/5a82515ad2484ceda7361ede7ad3a5c3
Autor:
László Ducza, Andrea Gajtkó, Krisztina Hegedűs, Erzsébet Bakk, Gréta Kis, Botond Gaál, Roland Takács, Péter Szücs, Klára Matesz, Krisztina Holló
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
ObjectiveIntense inflammation may result in pain, which manifests as spinal central sensitization. There is growing evidence that purinergic signaling plays a pivotal role in the orchestration of pain processing. Over the last decade the ionotropic P
Externí odkaz:
https://doaj.org/article/b375bf0966dd4d4f8fb3f83fe0c63d2b
Autor:
Andrea Xue, István Lénárt, Judit Kincs, Hajnalka Szabó, Andrea Párniczky, István Balogh, Anna Deák, Péter Béla Monostori, Krisztina Hegedűs, Attila J. Szabó, Ildikó Szatmári
Publikováno v:
International Journal of Neonatal Screening, Vol 9, Iss 3, p 47 (2023)
The aim of this study is to evaluate the strategy of the cystic fibrosis newborn screening (CFNBS) programme in Hungary based on the results of the first year of screening. A combined immunoreactive trypsinogen (IRT) and pancreatitis-associated prote
Externí odkaz:
https://doaj.org/article/33e10d86ad0c4f319a9b3710cff1f77c
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
It is now widely accepted that the glial cells of the central nervous system (CNS) are key players in many processes, especially when they are activated via neuron-glia or glia-glia interactions. In turn, many of the glia-derived pro-inflammatory cyt
Externí odkaz:
https://doaj.org/article/061f72718ea14657be7b75a51eb5a18c
Autor:
László Ducza, Péter Szücs, Krisztina Hegedűs, Erzsébet Bakk, Andrea Gajtkó, Ildikó Wéber, Krisztina Holló
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11408 (2021)
Our earlier findings revealed that interleukin-1 receptor type-1 (IL-1R1) was overexpressed in spinal neurons, and IL-1R1-deficient mice showed significant attenuation of thermal and mechanical allodynia during the course of the Complete Freund adjuv
Externí odkaz:
https://doaj.org/article/0972b4475540444a9db62909573ac717
Autor:
Krisztina Holló, László Ducza, Zoltán Hegyi, Klaudia Dócs, Krisztina Hegedűs, Erzsébet Bakk, Ildikó Papp, Gréta Kis, Zoltán Mészár, Zsuzsanna Bardóczi, Miklós Antal
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-18 (2017)
Abstract Background All known biological functions of the pro-inflammatory cytokine interleukin-1β (IL-1β) are mediated by type 1 interleukin receptor (IL-1R1). IL-1β–IL-1R1 signaling modulates various neuronal functions including spinal pain pr
Externí odkaz:
https://doaj.org/article/5f71ac961e414590af363aec6a5d67fa
Autor:
Szabolcs Takáts, Gábor Glatz, Győző Szenci, Attila Boda, Gábor V Horváth, Krisztina Hegedűs, Attila L Kovács, Gábor Juhász
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007359 (2018)
The autophagosomal SNARE Syntaxin17 (Syx17) forms a complex with Snap29 and Vamp7/8 to promote autophagosome-lysosome fusion via multiple interactions with the tethering complex HOPS. Here we demonstrate that, unexpectedly, one more SNARE (Ykt6) is a
Externí odkaz:
https://doaj.org/article/c105dfdd5fc140ab8e0168a0b60d600b
Autor:
Péter Lőrincz, Zsolt Lakatos, Ágnes Varga, Tamás Maruzs, Zsófia Simon-Vecsei, Zsuzsanna Darula, Péter Benkő, Gábor Csordás, Mónika Lippai, István Andó, Krisztina Hegedűs, Katalin F Medzihradszky, Szabolcs Takáts, Gábor Juhász
Publikováno v:
eLife, Vol 5 (2016)
Yeast studies identified two heterohexameric tethering complexes, which consist of 4 shared (Vps11, Vps16, Vps18 and Vps33) and 2 specific subunits: Vps3 and Vps8 (CORVET) versus Vps39 and Vps41 (HOPS). CORVET is an early and HOPS is a late endosomal
Externí odkaz:
https://doaj.org/article/5a643aec519e4f7a88ef63b7bf95f7a0
Publikováno v:
PLoS Genetics, Vol 9, Iss 8, p e1003664 (2013)
Autophagy, a lysosomal self-degradation and recycling pathway, plays dual roles in tumorigenesis. Autophagy deficiency predisposes to cancer, at least in part, through accumulation of the selective autophagy cargo p62, leading to activation of antiox
Externí odkaz:
https://doaj.org/article/49fdca3cba7e4c62b9d51cc4efbe9b30
Publikováno v:
Virus research. 312
The discovery and description of a pararetroviroid associated with carnation stunt was one of the most outstanding achievements gained by the research team directed by Ricardo Flores, as it opened up a whole new world in plant virology and quickly le