Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Krisztina Futosi"'
Autor:
Krisztina Futosi, Boglárka Bajza, Dorottya Deli, András Erdélyi, Simon Tusnády, Attila Mócsai
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Tyrosine kinases are crucial signaling components of diverse biological processes and are major therapeutic targets in various malignancies and immune-mediated disorders. A critical step of development of novel tyrosine kinase inhibitors is the trans
Externí odkaz:
https://doaj.org/article/f86c2c0ba1da448a8cfb486b12c0a640
Autor:
Tamás Németh, Krisztina Futosi, Marcell Szabó, Petra Aradi, Takashi Saito, Attila Mócsai, Zoltán Jakus
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Activating Fcγ receptors associated with Fc receptor γ-chain (FcRγ) are critical for mediating neutrophil effector functions in immune complex-mediated autoimmune diseases. FcRγ contains ITAM tyrosines and the in vivo role of these tyrosines has
Externí odkaz:
https://doaj.org/article/018aa1ec71b545fd9813b6d095273d55
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Neutrophils play an important role in antimicrobial host defence but can also contribute to non-infectious inflammatory processes. Here the authors show that adaptor protein CARD9 expressed in neutrophils is involved in the development of sterile aut
Externí odkaz:
https://doaj.org/article/94c8db3bf3c744779c35e4047064e4a3
Autor:
Tamás Németh, Krisztina Futosi, Kata Szilveszter, Olivér Vilinovszki, Levente Kiss-Pápai, Attila Mócsai
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Autoantibody production and autoantibody-mediated inflammation are hallmarks of a number of autoimmune diseases. The K/BxN serum-transfer arthritis is one of the most widely used models of the effector phase of autoantibody-induced pathology. Several
Externí odkaz:
https://doaj.org/article/e78286af00874d5d8ec39239254839ad
Autor:
Attila Varga, Pál Gyulavári, Zoltán Greff, Krisztina Futosi, Tamás Németh, Laura Simon-Szabó, Krisztina Kerekes, Csaba Szántai-Kis, Diána Brauswetter, Márton Kokas, Gábor Borbély, Anna Erdei, Attila Mócsai, György Kéri, Tibor Vántus
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144792 (2015)
Externí odkaz:
https://doaj.org/article/55ac64e255ec4adb9ce3d6c16ecbc5c2
Autor:
Attila Varga, Pál Gyulavári, Zoltán Greff, Krisztina Futosi, Tamás Németh, Laura Simon-Szabó, Krisztina Kerekes, Csaba Szántai-Kis, Diána Brauswetter, Márton Kokas, Gábor Borbély, Anna Erdei, Attila Mócsai, György Kéri, Tibor Vántus
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124234 (2015)
Emerging evidence suggests that the vascular endothelial growth factor receptor 2 (VEGFR2) and protein kinase D1 (PKD1) signaling axis plays a critical role in normal and pathological angiogenesis and inflammation related processes. Despite all effor
Externí odkaz:
https://doaj.org/article/e59f67d585014cf3805d900a5d2cab4d
Autor:
Péter K Jani, Erika Kajdácsi, Márton Megyeri, József Dobó, Zoltán Doleschall, Krisztina Futosi, Csaba I Tímár, Attila Mócsai, Veronika Makó, Péter Gál, László Cervenak
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87104 (2014)
Microbial infection urges prompt intervention by the immune system. The complement cascade and neutrophil granulocytes are the predominant contributors to this immediate anti-microbial action. We have previously shown that mannan-binding lectin-assoc
Externí odkaz:
https://doaj.org/article/5dd880daea6345e4b28f9bd651d6ceb8
Autor:
Krisztina Futosi, Tamás Németh, Ádám I. Horváth, Clare L. Abram, Simon Tusnády, Clifford A. Lowell, Zsuzsanna Helyes, Attila Mócsai
Publikováno v:
Journal of Experimental Medicine. 220
Autoinflammatory diseases include a number of monogenic systemic inflammatory diseases, as well as acquired autoinflammatory diseases such as gout. Here, we show that the myeloid Src-family kinases Hck, Fgr, and Lyn are critical for experimental mode
Autor:
Marcell Szabó, Zoltán Jakus, Krisztina Futosi, Takashi Saito, Attila Mócsai, Petra Aradi, Tamás Németh
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Activating Fcγ receptors associated with Fc receptor γ-chain (FcRγ) are critical for mediating neutrophil effector functions in immune complex-mediated autoimmune diseases. FcRγ contains ITAM tyrosines and the in vivo role of these tyrosines has
Autor:
Krisztina Futosi, Attila Mócsai
Publikováno v:
Immunological Reviews. 273:121-139
Neutrophils play a critical role in antimicrobial host defense, but their improper activation also contributes to inflammation-induced tissue damage. Therefore, understanding neutrophil biology is important for the understanding, diagnosis, and thera