Výsledky vyhledávání - "Krisztina B, Gecse"

Akademický článek

Subcutaneous vedolizumab interval extension in inflammatory bowel disease patients: a case series

Autor: Suzanne I. Anjie, Krisztina B. Gecse, Cyriel Y. Ponsioen, Mark Löwenberg, Geert R. D’Haens

Publikováno v: Therapeutic Advances in Gastroenterology, Vol 17 (2024)

Subcutaneous vedolizumab has demonstrated efficacy as a maintenance therapy in inflammatory bowel disease (IBD). However, data on the extension of subcutaneous vedolizumab injection intervals are lacking. Here, we present the first real-world data on

Externí odkaz: https://doaj.org/article/cb95d418daec493d8e013e6398779063

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Akademický článek

Tofacitinib as a maintenance therapy in patients with ulcerative colitis stratified by OCTAVE Sustain baseline Mayo endoscopic subscore

Autor: Scott D. Lee, Jessica R. Allegretti, Flavio Steinwurz, Susan B. Connelly, Nervin Lawendy, Jerome Paulissen, Krisztina B. Gecse

Publikováno v: BMC Gastroenterology, Vol 23, Iss 1, Pp 1-12 (2023)

Abstract Background Tofacitinib is an oral small molecule Janus kinase inhibitor for the treatment of ulcerative colitis. We evaluated tofacitinib efficacy and safety in the 52-week maintenance study, OCTAVE Sustain, by baseline Mayo endoscopic subsc

Externí odkaz: https://doaj.org/article/9411950b9c8d41e883962ad33a442508

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Akademický článek

Short-term anti-TNF therapy with surgical closure versus anti-TNF therapy alone for Crohn's perianal fistulas (PISA-II): long-term outcomes of an international, multicentre patient preference, randomised controlled trialResearch in context

Autor: Elise M. Meima - van Praag, Marte A.J. Becker, Kyra L. van Rijn, Karin A.T.G.M. Wasmann, Jaap Stoker, Geert R.A.M. D'Haens, Cyriel Y. Ponsioen, Krisztina B. Gecse, Marcel G.W. Dijkgraaf, Antonino Spinelli, Silvio Danese, Willem A. Bemelman, Christianne J. Buskens

Publikováno v: EClinicalMedicine, Vol 61, Iss , Pp 102045- (2023)

Summary: Background: The PISA-II trial showed that short-term anti-tumour necrosis factor (anti-TNF) therapy followed by surgical closure induces radiological healing of perianal fistulas in patients with Crohn's disease more frequently than anti-TNF

Externí odkaz: https://doaj.org/article/443912d0f5ce4ab0b569b0daebb28e7d

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Akademický článek

Disc‐like lesions in the intestinal tract after renal transplantation

Autor: Arjan J. Kwakernaak, Rob W. van derPluijm, Neelke C. van der Weerd, Lianne Koens, Wytske M. Westra, Krisztina B. Gecse, Ankie Kleinjan

Publikováno v: Clinical Case Reports, Vol 10, Iss 4, Pp n/a-n/a (2022)

Abstract We report a case of intestinal lesions in a patient with a history of lupus nephritis and renal transplantation. Biopsy revealed an EBV‐driven post‐transplant lymphoproliferative disease (PTLD). An EBV‐driven PTLD is a major complicati

Externí odkaz: https://doaj.org/article/b71db720359f40e28ed8e757629a76bb

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Akademický článek

Knotless seton for perianal fistulas: feasibility and effect on perianal disease activity

Autor: Merel E. Stellingwerf, Michiel T. J. Bak, E. Joline de Groof, Christianne J. Buskens, Charlotte B. H. Molenaar, Krisztina B. Gecse, Willem Nerkens, Tim Horeman, Willem A. Bemelman

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)

Abstract Patients with perianal fistulas are frequently treated by a knotted seton which is well-known for causing complaints. We aimed to assess the feasibility of the knotless SuperSeton and advantages with respect to perianal disease activity. In

Externí odkaz: https://doaj.org/article/3d19677c3f674611a0c9ab11c693dd1a

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Intestinal ultrasound detects an increased diameter and submucosal layer thickness in the appendix of patients with ulcerative colitis compared to healthy controls – a prospective cohort study

Autor: Maud A. Reijntjes, Floris A. E. de Voogd, Willem A. Bemelman, Roel Hompes, Geert d'Haens, Christianne J. Buskens, Krisztina B. Gecse

Publikováno v: Alimentary Pharmacology and Therapeutics, 57(1), 127-135. Wiley-Blackwell

Background: Increasing evidence suggests that appendicectomy as alternative treatment for ulcerative colitis (UC), especially in patients with histopathological appendiceal inflammation. Intestinal ultrasound (IUS) is a non-invasive diagnostic modali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b27873dbbfed40f1a56d4b9b17934f39
http://www.scopus.com/inward/record.url?scp=85141361209&partnerID=8YFLogxK

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Appropriateness of Medical and Surgical Treatments for Chronic Pouchitis Using RAND/UCLA Appropriateness Methodology

Autor: Gaurav Syal, Miles P. Sparrow, Fernando Velayos, Adam S. Cheifetz, Shane Devlin, Peter M. Irving, Gilaad G. Kaplan, Laura E. Raffals, Thomas Ullman, Krisztina B. Gecse, Phillip R. Fleshner, Amy L. Lightner, Corey A. Siegel, Gil Y. Melmed

Publikováno v: Digestive diseases and sciences, 67(10), 4687-4694. Springer New York

Background and Aims: The treatment of chronic pouchitis remains a challenge due to the paucity of high-quality studies. We aimed to provide guidance for clinicians on the appropriateness of medical and surgical treatments in chronic pouchitis. Method

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92217c983c0a8903a7017c785dc7e2c
http://www.scopus.com/inward/record.url?scp=85122854439&partnerID=8YFLogxK

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Akademický článek

Drug persistence and need for dose intensification to adalimumab therapy; the importance of therapeutic drug monitoring in inflammatory bowel diseases

Autor: Lorant Gonczi, Zsuzsanna Kurti, Mariann Rutka, Zsuzsanna Vegh, Klaudia Farkas, Barbara D. Lovasz, Petra A. Golovics, Krisztina B. Gecse, Balazs Szalay, Tamas Molnar, Peter L. Lakatos

Publikováno v: BMC Gastroenterology, Vol 17, Iss 1, Pp 1-7 (2017)

Abstract Background Therapeutic drug monitoring (TDM) aid therapeutic decision making in patients with inflammatory bowel disease (IBD) who lose response to anti-TNF therapy. Our aim was to evaluate the frequency and predictive factors of loss of res

Externí odkaz: https://doaj.org/article/48030799dcbf4f5f9cdd163826762379

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Short-term anti-TNF therapy with surgical closure versus anti-TNF therapy in the treatment of perianal fistulas in Crohn's disease (PISA-II)

Autor: Elise M Meima-van Praag, Kyra L van Rijn, Karin A T G M Wasmann, Harmanna J Snijder, Jaap Stoker, Geert R D'Haens, Krisztina B Gecse, Michael F Gerhards, Jeroen M Jansen, Marcel G W Dijkgraaf, Jarmila D W van der Bilt, Marco W Mundt, Antonino Spinelli, Silvio Danese, Willem A Bemelman, Christianne J Buskens

Publikováno v: The Lancet Gastroenterology and Hepatology, 7(7), 617-626. Elsevier Ltd
Meima-van Praag, E M, van Rijn, K L, Wasmann, K A T G M, Snijder, H J, Stoker, J, D'Haens, G R, Gecse, K B, Gerhards, M F, Jansen, J M, Dijkgraaf, M G W, van der Bilt, J D W, Mundt, M W, Spinelli, A, Danese, S, Bemelman, W A & Buskens, C J 2022, ' Short-term anti-TNF therapy with surgical closure versus anti-TNF therapy in the treatment of perianal fistulas in Crohn's disease (PISA-II) : a patient preference randomised trial ', The Lancet Gastroenterology and Hepatology, vol. 7, no. 7, pp. 617-626 . https://doi.org/10.1016/S2468-1253(22)00088-7

Background: Guidelines on Crohn's perianal fistulas recommend anti-tumour necrosis factor (TNF) treatment and suggest considering surgical closure for patients with surgically amenable disease. However, long-term outcomes following these two strategi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3f8e5b2dc14438623e37d83c4efc8b
http://www.scopus.com/inward/record.url?scp=85129321342&partnerID=8YFLogxK

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