Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s)

Autor: Johan Øvrevik, Magne Refsnes, Dominique Lagadic-Gossmann, Jørn A. Holme, Eric Le Ferrec, Bendik Christian Brinchmann, Klara Kukowski, Alena Kubátová, Krisztina Szöke, Arno C. Gutleb, Jan E. Brinchmann, Tonje Skuland, Mia H. Rambøl, Marit Låg, Elisa Moschini, Per E. Schwarze

Publikováno v: Particle and Fibre Toxicology, Vol 15, Iss 1, Pp 1-17 (2018)
Particle and Fibre Toxicology
Particle and Fibre Toxicology, 2018, 15 (1), pp.21. ⟨10.1186/s12989-018-0257-1⟩
Particle and Fibre Toxicology, BioMed Central, 2018, 15 (1), pp.21. ⟨10.1186/s12989-018-0257-1⟩

Background Exposure to traffic-derived particulate matter (PM), such as diesel exhaust particles (DEP), is a leading environmental cause of cardiovascular disease (CVD), and may contribute to endothelial dysfunction and development of atherosclerosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3fbec240e80ef4cdbd1af45ec5ad10
http://link.springer.com/article/10.1186/s12989-018-0257-1

3D Bioprinted hydrogel model incorporating β-tricalcium phosphate for calcified cartilage tissue engineering

Autor: Jakub Jaroszewicz, Marco Costantini, Krisztina Szöke, Marcin Heljak, Ewa Kijeńska, Alicja Kosik-Kozioł, Andrea Barbetta, Jan E. Brinchmann, Wojciech Święszkowski, Anna Mróz, Nadine Frerker, Joanna Idaszek

One promising strategy to reconstruct osteochondral defects relies on 3D bioprinted three-zonal structures comprised of hyaline cartilage, calcified cartilage, and subchondral bone. So far, several studies have pursued the regeneration of either hyal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fd0bb5574c0885b8a85510966fd967
http://hdl.handle.net/11573/1277516

3D bioprinting of BM-MSCs-loaded ECM biomimetic hydrogels for in vitro neocartilage formation

Autor: Marco Costantini, Mariella Dentini, Jakub Jaroszewicz, Wojciech Święszkowski, Joanna Idaszek, Krisztina Szöke, Jan E. Brinchmann, Andrea Barbetta

Publikováno v: Biofabrication. 8(3)

In this work we demonstrate how to print 3D biomimetic hydrogel scaffolds for cartilage tissue engineering with high cell density (>10(7) cells ml(-1)), high cell viability (85 ÷ 90%) and high printing resolution (≈100 μm) through a two coaxial-n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5612f2cda7644400e01292c5295d686
https://pubmed.ncbi.nlm.nih.gov/27431574

Phenotype and Gene Expression of Human Mesenchymal Stem Cells in Alginate Scaffolds

Autor: Krisztina Szöke, Katrine Frønsdal, Jan Egil Melvik, Shivali Duggal, Aboulghassem Shahdadfar, Jan E. Brinchmann

Publikováno v: Tissue Engineering Part A. 15:1763-1773

Human mesenchymal stem cells (MSC) are popular candidates for tissue engineering. MSC are defined by their properties in two-dimensional (2D) culture systems. Cells in 2D are known to differ from their in vivo counterparts in cell shape, proliferatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd7ec7b8329dc5ae1bc5357fbaf19cf
https://doi.org/10.1089/ten.tea.2008.0306

Autologous cell sources in therapeutic vasculogenesis: In vitro and in vivo comparison of endothelial colony-forming cells from peripheral blood and endothelial cells isolated from adipose tissue

Autor: Krisztina Szöke, Jan E. Brinchmann, Esben Østrup, Andreas Reinisch, Finn P. Reinholt

Publikováno v: Cytotherapy. 18(2)

Background aims. Autologous endothelial cells are promising alternative angiogenic cell sources in trials of therapeutic vasculogenesis, in the treatment of vascular diseases and in the field of tissue engineering. A population of endothelial cells (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cb2a636ed627fb5b18c3e90cbfbad1
https://pubmed.ncbi.nlm.nih.gov/26669908