Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Krisztian Stadler"'
Autor:
Elizabeth R. M. Zunica, Christopher L. Axelrod, Eunhan Cho, Guillaume Spielmann, Gangarao Davuluri, Stephanie J. Alexopoulos, Martina Beretta, Kyle L. Hoehn, Wagner S. Dantas, Krisztian Stadler, William T. King, Kathryn Pergola, Brian A. Irving, Ingeborg M. Langohr, Shengping Yang, Charles L. Hoppel, L. Anne Gilmore, John P. Kirwan
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-20 (2021)
Abstract Background Enhanced metabolic plasticity and diversification of energy production is a hallmark of highly proliferative breast cancers. This contributes to poor pharmacotherapy efficacy, recurrence, and metastases. We have previously identif
Externí odkaz:
https://doaj.org/article/73646908050a40a890022b3871277182
Autor:
Allison McCrimmon, Sydney Corbin, Bindesh Shrestha, Gregory Roman, Suraj Dhungana, Krisztian Stadler
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102520- (2022)
While it is generally accepted that oxidative stress impacts the diabetic kidney and contributes to pathogenesis, there is a substantial lack of knowledge about the molecular entity and anatomic location of a variety of reactive species. Here we prov
Externí odkaz:
https://doaj.org/article/8126f0383b694fe98b6d4fda2ad2057d
Autor:
Allison McCrimmon, Kerin M. Cahill, Claudia Kruger, Margaret E. Mangelli, Emily Bouffard, Timothy Dobroski, Kelly N. Michanczyk, Susan J. Burke, Robert C. Noland, Daria V. Ilatovskaya, Krisztian Stadler
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
The importance of healthy mitochondrial function is implicated in the prevention of chronic kidney disease (CKD) and diabetic kidney disease (DKD). Sex differences also play important roles in DKD. Our previous studies revealed that mitochondrial sub
Externí odkaz:
https://doaj.org/article/e2721d6acb4b423b88604d734887d262
Autor:
Nahla Issa, Gabriel Lachance, Kerstin Bellmann, Mathieu Laplante, Krisztian Stadler, André Marette
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2321-2328 (2018)
NADPH oxidase (NOX) enzymes are one of the major superoxide-generating systems in cells. NOX-generated superoxide has been suggested to promote insulin resistance in the liver. However, the role of NOX enzymes in mediating metabolic dysfunction in ot
Externí odkaz:
https://doaj.org/article/0f8d758903b346999214d1b9b62f74d0
Autor:
Christopher L Axelrod, William T King, Gangarao Davuluri, Robert C Noland, Jacob Hall, Michaela Hull, Wagner S Dantas, Elizabeth RM Zunica, Stephanie J Alexopoulos, Kyle L Hoehn, Ingeborg Langohr, Krisztian Stadler, Haylee Doyle, Eva Schmidt, Stephan Nieuwoudt, Kelly Fitzgerald, Kathryn Pergola, Hisashi Fujioka, Jacob T Mey, Ciaran Fealy, Anny Mulya, Robbie Beyl, Charles L Hoppel, John P Kirwan
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 7, Pp n/a-n/a (2020)
Abstract Obesity is a leading cause of preventable death worldwide. Despite this, current strategies for the treatment of obesity remain ineffective at achieving long‐term weight control. This is due, in part, to difficulties in identifying tolerab
Externí odkaz:
https://doaj.org/article/61fe5cb6b2dd4631b169f643148abc19
Autor:
Mark Domondon, Iuliia Polina, Anna B. Nikiforova, Regina F. Sultanova, Claudia Kruger, Valeriia Y. Vasileva, Mikhail V. Fomin, Gyda C. Beeson, Anna-Liisa Nieminen, Nancy Smythe, Eduardo N. Maldonado, Krisztian Stadler, Daria V. Ilatovskaya
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
Salt-sensitive (SS) hypertension is accompanied with an early onset of proteinuria, which results from the loss of glomerular podocytes. Here, we hypothesized that glomerular damage in the SS hypertension occurs in part due to mitochondria dysfunctio
Externí odkaz:
https://doaj.org/article/193ff7df453c485fad4d08bf45381923
Autor:
Susan J. Burke, Heidi M. Batdorf, David H. Burk, Thomas M. Martin, Tamra Mendoza, Krisztian Stadler, Wateen Alami, Michael D. Karlstad, Matthew J. Robson, Randy D. Blakely, Randall L. Mynatt, J. Jason Collier
Publikováno v:
Molecular Metabolism, Vol 14, Iss , Pp 95-107 (2018)
Objective: Pancreatic tissue, and islets in particular, are enriched in expression of the interleukin-1 receptor type I (IL-1R). Because of this enrichment, islet β-cells are exquisitely sensitive to the IL-1R ligands IL-1α and IL-1β, suggesting t
Externí odkaz:
https://doaj.org/article/3e446786db4e433f84a292436eed3c59
Autor:
Claudia Kruger, Susan J. Burke, J. Jason Collier, Trang-Tiffany Nguyen, J. Michael Salbaum, Krisztian Stadler
Publikováno v:
Redox Biology, Vol 16, Iss , Pp 248-254 (2018)
Early podocyte loss is characteristic of chronic kidney diseases (CKD) in obesity and diabetes. Since treatments for hyperglycemia and hypertension do not prevent podocyte loss, there must be additional factors causing podocyte depletion. The role of
Externí odkaz:
https://doaj.org/article/eb10cfc04cfe4dc7afdbca22e77061fe
Autor:
Qin Wang, Haiying Qi, Yiming Wu, Liping Yu, Rihab Bouchareb, Shuyu Li, Emelie Lassén, Gabriella Casalena, Krisztian Stadler, Kerstin Ebefors, Zhengzi Yi, Shaolin Shi, Fadi Salem, Ronald Gordon, Lu Lu, Robert W. Williams, Jeremy Duffield, Weijia Zhang, Yuval Itan, Erwin Böttinger, Ilse Daehn
Publikováno v:
Nature Metabolism. 5:607-625
Autor:
Denisha R. Spires, Ryan S. Schibalski, Regina F. Sultanova, Mark Domondon, Daria Lysikova, Krisztian Stadler, Daria Ilatovskaya
Publikováno v:
The FASEB Journal. 36