Výsledky vyhledávání - "Krisztian Homicsko"

Akademický článek

Probing the killing potency of tumor-infiltrating lymphocytes on microarrayed colorectal cancer tumoroids

Autor: Devanjali Dutta, L. Francisco Lorenzo-Martín, François Rivest, Nicolas Broguiere, Lucie Tillard, Simone Ragusa, Nathalie Brandenberg, Sylke Höhnel, Damien Saugy, Sylvie Rusakiewicz, Krisztian Homicsko, George Coukos, Matthias P. Lutolf

Publikováno v: npj Precision Oncology, Vol 8, Iss 1, Pp 1-7 (2024)

Abstract Immunotherapy has emerged as a new standard of care for certain cancer patients with specific cellular and molecular makeups. However, there is still an unmet need for ex vivo models able to readily assess the effectiveness of immunotherapeu

Externí odkaz: https://doaj.org/article/500b8010d8694a5e80a921b03b5440e1

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Akademický článek

Nanoplasmonic Single‐Tumoroid Microarray for Real‐Time Secretion Analysis

Autor: Yen‐Cheng Liu, Saeid Ansaryan, Jiayi Tan, Nicolas Broguiere, Luis Francisco Lorenzo‐Martín, Krisztian Homicsko, George Coukos, Matthias P. Lütolf, Hatice Altug

Publikováno v: Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)

Abstract Organoid tumor models have emerged as a powerful tool in the fields of biology and medicine as such 3D structures grown from tumor cells recapitulate better tumor characteristics, making these tumoroids unique for personalized cancer researc

Externí odkaz: https://doaj.org/article/7f3287aaf2f046a1b562b7eb9bc79781

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Akademický článek

Deep and lasting response and acquired resistance to BRAFV600E targeting in a low-grade ovarian cancer patient

Autor: Sandro Anchisi, Anita Wolfer, Bettina Bisig, Edoardo Missiglia, Amine Tiab, Ehab Mohamed Kamel, Olivier Michielin, George Coukos, Krisztian Homicsko

Publikováno v: Cancer Biology & Therapy, Vol 24, Iss 1 (2023)

The treatment of BRAFV600E mutant melanoma has been revolutionized by BRAF inhibitors. Furthermore, the BRAF/MEK combination has shown further improvement in clinical outcomes in advanced and in adjuvant melanoma patients. In low-grade ovarian tumors

Externí odkaz: https://doaj.org/article/3a81ea454bf54dd6b4cd935fc04e1029

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Akademický článek

PD-1-expressing macrophages and CD8 T cells are independent predictors of clinical benefit from PD-1 inhibition in advanced mesothelioma

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)

Background Few tissue biomarkers exist to date that could enrich patient with cancer populations to benefit from immune checkpoint blockade by programmed cell death protein 1/ligand-1 (PD-/L-1) inhibitors. PD-L1 expression has value in this context i

Externí odkaz: https://doaj.org/article/6dd7fca327104b5ea4d8c47266ef755b

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Akademický článek

First communication on the efficacy of combined 177Lutetium-PSMA with immunotherapy outside prostate cancer

Autor: John Prior, Solange Peters, Krisztian Homicsko, Sarah Boughdad, Niklaus Schaefer, Antonia Digklia, Clarisse Dromain, Mounir Trimech, Ana Dolcan

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)

Prostate-specific membrane antigen (PSMA)-targeted radioligand therapy is a validated treatment option for patients with advanced prostate cancer. Although PSMA expression is not limited to prostate tissue, little is known about its relevance to othe

Externí odkaz: https://doaj.org/article/50a540258e4148daa7709fb78b369abc

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Akademický článek

Ovarian cancer with high-level focal ERBB2 amplification responds to trastuzumab and pertuzumab

Autor: Laure Thouvenin, Mélinda Charrier, Sophie Clement, Yann Christinat, Jean-Christophe Tille, Mauro Frigeri, Krisztian Homicsko, Olivier Michielin, Alexandre Bodmer, Pierre O. Chappuis, Thomas A. McKee, Petros Tsantoulis

Publikováno v: Gynecologic Oncology Reports, Vol 37, Iss , Pp 100787- (2021)

Epithelial ovarian cancer (EOC) is usually diagnosed at an advanced stage and significantly contributes to cancer mortality in women. Despite multimodal treatment associating chemotherapy and surgery, most patients ultimately progress and require pal

Externí odkaz: https://doaj.org/article/bba19669ae314c2babf356bc5665ae51

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