Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Kristy S Hwang"'
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0282684 (2023)
Patients with Parkinson's disease undergo a loss of melanized neurons in substantia nigra pars compacta and locus coeruleus. Very few studies have assessed substantia nigra pars compacta and locus coeruleus pathology in Parkinson's disease simultaneo
Externí odkaz:
https://doaj.org/article/5d11491dec514b478ed05c9c74c1dc54
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
IntroductionStriatal dopamine transporter (DAT) imaging using 123I-ioflupane single photon positron emitted computed tomography (SPECT) (DaTScan, GE) identifies 5−20% of newly diagnosed Parkinson’s disease (PD) subjects enrolling in clinical stud
Externí odkaz:
https://doaj.org/article/9833565d720f4f38b70f3ee490440e10
Autor:
Naira Goukasian, Shai Porat, Anna Blanken, David Avila, Dimitar Zlatev, Sona Hurtz, Kristy S. Hwang, Jonathan Pierce, Shantanu H. Joshi, Ellen Woo, Liana G. Apostolova
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 9, Iss 2, Pp 281-293 (2019)
We analyzed structural magnetic resonance imaging data from 58 cognitively normal and 101 mild cognitive impairment subjects. We used a general linear regression model to study the association between cognitive performance with hippocampal atrophy an
Externí odkaz:
https://doaj.org/article/16a7535e09a040218da6b3e464a18cd5
Autor:
Jonathan Grotts, Naira Goukasian, Kristy S. Hwang, Tamineh Romero, Triet M. Do, Jenna R. Groh, Daniel R. Bateman, Liana G. Apostolova
Publikováno v:
BMJ Open, Vol 9, Iss 12 (2019)
Objective To investigate the relationship between amyloid burden and frequency of existing and incidence of new neuropsychiatric symptoms (NPS) in elderly with and without cognitive decline.Methods 275 cognitively normal controls (NC), 100 subjective
Externí odkaz:
https://doaj.org/article/8887216c10f44a21b9a74a0f4fe0ded3
Autor:
Sona Hurtz, Nicole Chow, Amity E. Watson, Johanne H. Somme, Naira Goukasian, Kristy S. Hwang, John Morra, David Elashoff, Sujuan Gao, Ronald C. Petersen, Paul S. Aisen, Paul M. Thompson, Liana G. Apostolova
Publikováno v:
NeuroImage: Clinical, Vol 21, Iss , Pp - (2019)
Background: Imaging techniques used to measure hippocampal atrophy are key to understanding the clinical progression of Alzheimer's disease (AD). Various semi-automated hippocampal segmentation techniques are available and require human expert input
Externí odkaz:
https://doaj.org/article/068a17dcaea0428ba92814974e9bbbe7
Autor:
Shai Porat, Naira Goukasian, Kristy S. Hwang, Theodore Zanto, Triet Do, Jonathan Pierce, Shantanu Joshi, Ellen Woo, Liana G. Apostolova
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 6, Iss 3, Pp 508-517 (2016)
Introduction: We investigated the effect dance experience may have on cortical gray matter thickness and cognitive performance in elderly participants with and without mild cognitive impairment (MCI). Methods: 39 cognitively normal and 48 MCI elderly
Externí odkaz:
https://doaj.org/article/14712ce8b58541d2b8a0f6887e63ada0
Autor:
Tugce Duran, Ellen Woo, Diana Otero, Shannon L. Risacher, Eddie Stage, Apoorva B. Sanjay, Kwangsik Nho, John D. West, Meredith L. Phillips, Naira Goukasian, Kristy S. Hwang, Liana G. Apostolova
Publikováno v:
Brain Imaging Behav
Metacognitive deficits affect Alzheimer’s disease (AD) patient safety and increase caregiver burden. The brain areas that support metacognition are not well understood. 112 participants from the Imaging and Genetic Biomarkers for AD (ImaGene) study
Autor:
Kristy S. Hwang, Andreas S. Lazaris, Jennifer A. Eastman, Edmond Teng, Paul M. Thompson, Karen H. Gylys, Gregory M. Cole, Liana G. Apostolova, Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 1, Iss 2, Pp 187-193 (2015)
Abstract Background Brain‐derived neurotrophic factor (BDNF) plays an important role in Alzheimer's disease (AD) and other neurodegenerative disorders. BDNF function is adversely affected by amyloid beta in AD. BDNF levels in brain and peripheral t
Externí odkaz:
https://doaj.org/article/e31b9276a6ce4b15827daa2eaa632fe4
Autor:
Liana G. Apostolova, Kristy S. Hwang, Omid Kohannim, David Avila, David Elashoff, Clifford R. Jack, Jr., Leslie Shaw, John Q. Trojanowski, Michael W. Weiner, Paul M. Thompson
Publikováno v:
NeuroImage: Clinical, Vol 4, Iss C, Pp 461-472 (2014)
Biomarkers are the only feasible way to detect and monitor presymptomatic Alzheimer's disease (AD). No single biomarker can predict future cognitive decline with an acceptable level of accuracy. In addition to designing powerful multimodal diagnostic
Externí odkaz:
https://doaj.org/article/de8308d678e340a88b432ada4cd2563a
Autor:
Dimitar V. Zlatev, Jonathan Pierce, Anna E. Blanken, Shai Porat, Shantanu H. Joshi, David Avila, Kristy S. Hwang, Liana G. Apostolova, Naira Goukasian, Sona Hurtz, Ellen Woo
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 9, Iss 2, Pp 281-293 (2019)
Dementia and Geriatric Cognitive Disorders EXTRA
Dementia and Geriatric Cognitive Disorders EXTRA
We analyzed structural magnetic resonance imaging data from 58 cognitively normal and 101 mild cognitive impairment subjects. We used a general linear regression model to study the association between cognitive performance with hippocampal atrophy an