Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Kristy R. Stengel"'
Autor:
Rachel E. Brown, Justin Jacobse, Shruti A. Anant, Koral M. Blunt, Bob Chen, Paige N. Vega, Chase T. Jones, Jennifer M. Pilat, Frank Revetta, Aidan H. Gorby, Kristy R. Stengel, Yash A. Choksi, Kimmo Palin, M. Blanca Piazuelo, Mary Kay Washington, Ken S. Lau, Jeremy A. Goettel, Scott W. Hiebert, Sarah P. Short, Christopher S. Williams
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Aberrant epithelial differentiation and regeneration contribute to colon pathologies, including inflammatory bowel disease (IBD) and colitis-associated cancer (CAC). Myeloid translocation gene 16 (MTG16, also known as CBFA2T3) is a transcriptional co
Externí odkaz:
https://doaj.org/article/5d314fb9ae044fb497de866e2b6326f8
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100530- (2021)
Summary: Transcriptional changes happen within minutes; however, RNAi or genetic deletion requires days to weeks before transcription networks can be analyzed. This limitation has made it challenging to distinguish direct from indirect targets of seq
Externí odkaz:
https://doaj.org/article/546831677cc14fa4bd874ec9d3d609e2
Autor:
Mark R. Boothby, Ariel Raybuck, Sung Hoon Cho, Kristy R. Stengel, Volker H. Haase, Scott Hiebert, Jingxin Li
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Accumulating evidence suggests that many immune responses are influenced by local nutrient concentrations in addition to the programming of intermediary metabolism within immune cells. Humoral immunity and germinal centers (GC) are settings in which
Externí odkaz:
https://doaj.org/article/1145f66379824603aee1bae944a95adf
Autor:
Yue Zhao, Qi Liu, Pankaj Acharya, Kristy R. Stengel, Quanhu Sheng, Xiaofan Zhou, Hojoong Kwak, Melissa A. Fischer, James E. Bradner, Stephen A. Strickland, Sanjay R. Mohan, Michael R. Savona, Bryan J. Venters, Ming-Ming Zhou, John T. Lis, Scott W. Hiebert
Publikováno v:
Cell Reports, Vol 16, Iss 7, Pp 2003-2016 (2016)
Bromodomain and extra-terminal domain (BET) family inhibitors offer an approach to treating hematological malignancies. We used precision nuclear run-on transcription sequencing (PRO-seq) to create high-resolution maps of active RNA polymerases acros
Externí odkaz:
https://doaj.org/article/cf9b89b3be554977ab7d018484f46c0c
Autor:
Ari M. Melnick, Hans-Guido Wendel, Olivier Elemento, Wayne Tam, Randy D. Gascoyne, Scott W. Hiebert, Rita Shaknovich, Robert G. Roeder, Chi-Shuen Chu, James W. Young, Sneh Sharma, Edward Holson, Janice E. Kranz, Kristy R. Stengel, David W. Scott, Daisuke Ennishi, Shenqiu Wang, David Poloway, Zhuoning Li, Cem Meydan, Matt Teater, Xabier Agirre, Ashley S. Doane, Ling Wang, Dylan McNally, Sara Parsa, Katerina Hatzi, Hsia-Yuan Ying, Huimin Geng, Ana Ortega-Molina, Yanwen Jiang
Supplementary Figure S1. Crebbp deficiency results in accelerated germinal center derived B-cell lymphoma development in mice. Supplementary Figure S2. Ep300 deficiency results in accelerated germinal center derived B-cell lymphoma development in mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454b834f82e2ea2602f9d0f040226cbc
https://doi.org/10.1158/2159-8290.22531458.v1
https://doi.org/10.1158/2159-8290.22531458.v1
Autor:
Ari M. Melnick, Hans-Guido Wendel, Olivier Elemento, Wayne Tam, Randy D. Gascoyne, Scott W. Hiebert, Rita Shaknovich, Robert G. Roeder, Chi-Shuen Chu, James W. Young, Sneh Sharma, Edward Holson, Janice E. Kranz, Kristy R. Stengel, David W. Scott, Daisuke Ennishi, Shenqiu Wang, David Poloway, Zhuoning Li, Cem Meydan, Matt Teater, Xabier Agirre, Ashley S. Doane, Ling Wang, Dylan McNally, Sara Parsa, Katerina Hatzi, Hsia-Yuan Ying, Huimin Geng, Ana Ortega-Molina, Yanwen Jiang
A list of CREBBP mutations in cohorts 1 and 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170541a36aea2225266b7c0ac1cd81df
https://doi.org/10.1158/2159-8290.22531446
https://doi.org/10.1158/2159-8290.22531446
Autor:
Monica L. Bomber, Jing Wang, Qi Liu, Kelly R. Barnett, Hillary M. Layden, Emily Hodges, Kristy R. Stengel, Scott W. Hiebert
Publikováno v:
Molecular Cell. 83:507-522.e6
Autor:
Maria Pia Arrate, Kelli L. Boyd, Susu Zhang, Haley E. Ramsey, Michael R. Savona, Agnieszka E. Gorska, Yue Zhao, Dalton L. Greenwood, Matthew C. Stubbs, Londa Fuller, Merrida A Childress, Jeffrey C. Rathmell, Phillip Liu, Kristy R. Stengel, Melissa A. Fischer, Scott W. Hiebert
Publikováno v:
Clinical Cancer Research. 27:598-607
Purpose: The BCL2 inhibitor, venetoclax, has transformed clinical care in acute myeloid leukemia (AML). However, subsets of patients do not respond or eventually acquire resistance. Venetoclax-based regimens can lead to considerable marrow suppressio
Autor:
Rachel E. Brown, Justin Jacobse, Shruti A. Anant, Koral M. Blunt, Bob Chen, Paige N. Vega, Chase T. Jones, Jennifer M. Pilat, Frank Revetta, Aidan H. Gorby, Kristy R. Stengel, Yash A. Choksi, Kimmo Palin, M. Blanca Piazuelo, Mary Kay Washington, Ken S. Lau, Jeremy A. Goettel, Scott W. Hiebert, Sarah P. Short, Christopher S. Williams
Publikováno v:
JCI insight. 7(10)
Aberrant epithelial differentiation and regeneration contribute to colon pathologies, including inflammatory bowel disease (iBD) and colitis-associated cancer (CAC). Myeloid translocation gene 16 (MTG16, also known as CBFA2T3) is a transcriptional co
Autor:
Rachel E. Brown, Justin Jacobse, Shruti A. Anant, Koral M. Blunt, Bob Chen, Paige N. Vega, Chase T. Jones, Jennifer M. Pilat, Frank Revetta, Aidan H. Gorby, Kristy R. Stengel, Yash A. Choksi, Kimmo Palin, M. Blanca Piazuelo, M. Kay Washington, Ken S. Lau, Jeremy A. Goettel, Scott W. Hiebert, Sarah P. Short, Christopher S. Williams
Aberrant epithelial differentiation and regeneration contribute to colon pathologies including inflammatory bowel disease (IBD) and colitis-associated cancer (CAC). MTG16 (CBFA2T3) is a transcriptional corepressor expressed in the colonic epithelium.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66ba49eb14941d18f8702c4fd6b947a9
https://doi.org/10.1101/2021.11.03.467178
https://doi.org/10.1101/2021.11.03.467178