Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kristy Parsons"'
Autor:
Alan C-Y Hsu, Kristy Parsons, Ian Barr, Sue Lowther, Deborah Middleton, Philip M Hansbro, Peter A B Wark
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32947 (2012)
Innate antiviral responses in bronchial epithelial cells (BECs) provide the first line of defense against respiratory viral infection and the effectiveness of this response is critically dependent on the type I interferons (IFNs). However the importa
Externí odkaz:
https://doaj.org/article/0eef907b001041e69763837f978366c0
Autor:
Joerg Mattes, Adam Collison, Luke Hatchwell, Jason Girkin, Nathan W. Bartlett, Junyao Li, Simon Phipps, Peter A. B. Wark, Sebastian L. Johnston, Kristy Parsons, Darryl A. Knight, Jie Zhang, Paul S. Foster
Publikováno v:
Thorax
Background Asthma exacerbations represent a significant disease burden and are commonly caused by rhinovirus (RV), which is sensed by Toll-like receptors (TLR) such as TLR7. Some asthmatics have impaired interferon (IFN) responses to RV, but the unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d8f6be50b39794ee5e9fbdcb8b1753
https://doi.org/10.1136/thoraxjnl-2014-205465
https://doi.org/10.1136/thoraxjnl-2014-205465
Autor:
Cristan Herbert, Kristy Parsons, Peter A. B. Wark, Rakesh K. Kumar, Martin P. Bucknall, Helen Rutlidge, Linda Garthwaite, Alexander M. Shadie, Brendan Halliburton
Publikováno v:
Respirology. 20:73-79
Background and objective Exposure to airborne particulate matter (PM) may promote development of childhood asthma and trigger acute exacerbations of existing asthma via injury to airway epithelial cells (AEC). Methods We compared the response of AEC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92e0689b5ea69fa6b3ff8ee48758397e
https://doi.org/10.1111/resp.12381
https://doi.org/10.1111/resp.12381
Publikováno v:
Clinical & Experimental Allergy. 44:91-101
SummaryBackground Rhinoviruses (RV) are the most common acute triggers of asthma, and airway epithelial cells are the primary site of infection. Asthmatic bronchial epithelial cells (BECs) have been found to have impaired innate immune responses to R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad7f14e3b25d8bbb24f024b71c69797
https://doi.org/10.1111/cea.12218
https://doi.org/10.1111/cea.12218
Publikováno v:
Respirology. 18:996-1002
Background and objective Infection is as an important trigger for acute asthma and chronic obstructive pulmonary disease (COPD). The aim of this article was to determine the prevalence and impact of virus and bacterial infections in acute asthma and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d86d2b6f150a2eb3bc354c84d6dd8c7
https://doi.org/10.1111/resp.12099
https://doi.org/10.1111/resp.12099
Publikováno v:
3.2 Airway Cell Biology and Immunopathology.
Asthma is characterised by chronic airway inflammation and increased susceptibility to virus infections, such as Rhinovirus (RV), consequently the airway epithelium is exposed to high levels of oxidative stress. The Mitochondria play a central role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::052b468489fedd05dbe03de45a4c0a6f
https://doi.org/10.1183/13993003.congress-2016.pa3989
https://doi.org/10.1183/13993003.congress-2016.pa3989
Autor:
Paul S. Foster, Peter A. B. Wark, J. Li, Sebastian L. Johnston, Adam Collison, Simon Phipps, Pereira A. De Siqueira, Kristy Parsons, Joerg Mattes, Nathan W. Bartlett, Luke Hatchwell, Jason Girkin
Publikováno v:
Respirology. 19:13-15
Introduction:Some asthmatics display impaired type 1 IFN responses and exaggerated inflammatory responses upon Rhinovirus (RV) infection, however, the molecular basis for these observations remain obscure despite intensive research. Recently, impaire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3665181fd262eceeaeae86549e9f385
https://doi.org/10.1111/resp.12262_2
https://doi.org/10.1111/resp.12262_2
Autor:
Thomas K. Wright, Vanessa M. McDonald, Lisa Wood, Jodie L. Simpson, Kristy Parsons, Peter A. B. Wark, Katherine J. Baines, Peter G. Gibson
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2015 (2015)
Mediators of Inflammation, Vol 2015 (2015)
Background. Innate immune antimicrobial peptides, includingβ-defensin-1, promote the chemotaxis and activation of several immune cells. The role ofβ-defensin-1 in asthma and chronic obstructive pulmonary disease (COPD) remains unclear.Methods. Indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc59751a940f32bd20fc0e9d0d3830e1
Autor:
Philip M. Hansbro, Alan Chen-Yu Hsu, Su-Ling Loo, Peter A. B. Wark, Kristy Parsons, Faezeh Fathi Aghdam
Publikováno v:
Human Respiratory Viral Infections ISBN: 9780429102875
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e41bdde420e8d819879f7bf02e643ee
https://doi.org/10.1201/b16778-3
https://doi.org/10.1201/b16778-3
Publikováno v:
Cytokine. 70:63
Pregnant women are particularly susceptible to influenza and the recent pandemic shows that poor outcomes including death continue to occur. The placenta releases the endogenous retroviral envelope protein syncytin-1, which has been demonstrated to h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe5a89563c73375028eeeddfc37125f5
https://doi.org/10.1016/j.cyto.2014.07.154
https://doi.org/10.1016/j.cyto.2014.07.154