Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kristy L. Hentchel"'
Autor:
John P. Lisher, Ho-Ching Tiffany Tsui, Smirla Ramos-Montañez, Kristy L. Hentchel, Julia E. Martin, Jonathan C. Trinidad, Malcolm E. Winkler, David P. Giedroc
Publikováno v:
mSphere, Vol 2, Iss 1 (2017)
ABSTRACT The catalase-negative, facultative anaerobe Streptococcus pneumoniae D39 is naturally resistant to hydrogen peroxide (H2O2) produced endogenously by pyruvate oxidase (SpxB). Here, we investigate the adaptive response to endogenously produced
Externí odkaz:
https://doaj.org/article/9b263744cdb6477bb91a837cfbe40d8f
Publikováno v:
Microbial Cell, Vol 2, Iss 11, Pp 451-453 (2015)
The extensive involvement of the reversible lysine acylation (RLA) system in metabolism has attracted the attention of investigators interested in understanding the fundamentals of prokaryotic and eukaryotic cell function. Research in this area of ce
Externí odkaz:
https://doaj.org/article/a1c0dc49d8b240b1b42fdbb6c06b352f
Publikováno v:
mBio, Vol 6, Iss 4 (2015)
ABSTRACT In Salmonella enterica, the reversible lysine acetylation (RLA) system is comprised of the protein acetyltransferase (Pat) and sirtuin deacetylase (CobB). RLA controls the activities of many proteins, including the acetyl coenzyme A (acetyl-
Externí odkaz:
https://doaj.org/article/e8cb9fced4a7495698ef3197fab45eb2
Autor:
Leila M. Reyes Ruiz, Aretha Fiebig, Kristy L. Hentchel, Patrick D. Curtis, Maureen L. Coleman, Sean Crosson
Bacterial genomes evolve in complex ecosystems and are best understood in this natural context, but replicating such conditions in the lab is challenging. We used transposon sequencing to define the fitness consequences of gene disruption in the bact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981c443c49d8db474031cccd2f84d730
https://europepmc.org/articles/PMC6331620/
https://europepmc.org/articles/PMC6331620/
Publikováno v:
Microbial Cell, Vol 2, Iss 11, Pp 451-453 (2015)
The extensive involvement of the reversible lysine acylation (RLA) system in metabolism has attracted the attention of investigators interested in understanding the fundamentals of prokaryotic and eukaryotic cell function. Research in this area of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96404b2a90874f490ad0aa26f7c25cac
http://microbialcell.com/researcharticles/complex-regulation-of-the-sirtuin-dependent-reversible-lysine-acetylation-system-of-salmonella-enterica/
http://microbialcell.com/researcharticles/complex-regulation-of-the-sirtuin-dependent-reversible-lysine-acetylation-system-of-salmonella-enterica/
Acetylation of small molecules is widespread in nature, and in some cases, cells use this process to detoxify harmful chemicals. Streptomyces species utilize a G cn5 N - a cetyl t ransferase (GNAT), known as Bar, to acetylate and detoxify a self-prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707a1cc225c4126410059275026f87e9
https://europepmc.org/articles/PMC5118915/
https://europepmc.org/articles/PMC5118915/
SUMMARY Acylation of biomolecules (e.g., proteins and small molecules) is a process that occurs in cells of all domains of life and has emerged as a critical mechanism for the control of many aspects of cellular physiology, including chromatin mainte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa93a76219aa87316d0c5880d2144f4
https://europepmc.org/articles/PMC4503791/
https://europepmc.org/articles/PMC4503791/
Publikováno v:
mBio
mBio, Vol 6, Iss 4 (2015)
mBio, Vol 6, Iss 4 (2015)
In Salmonella enterica, the reversible lysine acetylation (RLA) system is comprised of the protein acetyltransferase (Pat) and sirtuin deacetylase (CobB). RLA controls the activities of many proteins, including the acetyl coenzyme A (acetyl-CoA) synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5224e07c0f4db4d8bf91ca5d147ef74
http://europepmc.org/articles/PMC4513076
http://europepmc.org/articles/PMC4513076
Acetyl phosphate (AcP) is a small-molecule metabolite that can act as a phosphoryl group donor for response regulators of two-component systems (TCSs). The serious human respiratory pathogen Streptococcus pneumoniae (pneumococcus) synthesizes AcP by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4a57dc1e677398a57837d2deab6371
https://europepmc.org/articles/PMC3008541/
https://europepmc.org/articles/PMC3008541/