Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kristy L. Berry"'
Autor:
Adam B. Keeton, Xi Chen, Jacob Valiyaveettil, Chung-Hui Huang, Tyler E. Mattox, Khalda Fadlalla, Jeremy B. Foote, Donald J. Buchsbaum, Kristy L. Berry, Elmar Nurmemmedov, Ivan Babic, Vadim Gaponenko, Gregory Gorman, Lori Coward, Yulia Y. Maxuitenko, Forrest T. Smith, Gary A. Piazza
Publikováno v:
Cancer Research. 83:1658-1658
RAS is a critically important oncogenic protein that is mutated in approximately 1/3 of cancers resulting in aberrant activation of downstream signaling, which drives malignant transformation. Current molecular targeted therapeutics, and several in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c575ee184de91e1d147ec5071319885
https://doi.org/10.1158/1538-7445.am2023-1658
https://doi.org/10.1158/1538-7445.am2023-1658
Autor:
Adam B. Keeton, Rebecca Barber, Antonio Ward, Ileana V. Aragon, Alla Musiyenko, Joel Andrews, Wito Richter, Annelise M. Wilhite, Steve McClellan, Kevin Lee, Gary A. Piazza, Luciana Madeira da Silva, Jennifer Scalici, Elaine Gavin, Kristy L. Berry, Xi Chen
Publikováno v:
Cancer Research. 81:1213-1213
Objective: A leading theory for ovarian carcinogenesis proposes that the inflammation associated with incessant ovulation is a driver of oncogenesis. Consistent with this theory, epidemiological studies have shown that nonsteroidal anti-inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffb0460fddc46028d6d5cb7dca57bc4f
https://doi.org/10.1158/1538-7445.am2021-1213
https://doi.org/10.1158/1538-7445.am2021-1213
Autor:
Veronica Ramirez-Alcantara, Michael R. Boyd, Bing Zhu, Xi Chen, Kristy L. Berry, Antonio Ward, Tyler E. Mattox, Jacob Valiyaveettil, Adam B. Keeton, Gary A. Piazza, Yulia Maxuitenko
Publikováno v:
Cancer Research. 79:345-345
Oncogenic mutations in RAS genes result in an intracellular elevation of active RAS and increased cellular propagation through downstream signaling pathways responsible for tumor cell growth and survival. Mutations in KRAS drive over 90% of pancreati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f4b205b4bce128c24952a9563a60ca0
https://doi.org/10.1158/1538-7445.am2019-345
https://doi.org/10.1158/1538-7445.am2019-345
Autor:
Luciana Madeira da Silva, Tyler E. Mattox, Adam B. Keeton, Gary A. Piazza, Harry S. Cooper, Margie L. Clapper, Kristy L. Berry, Yulia Maxuitenko, Kevin A.W. Lee, Wen-Chi L. Chang, Bing Zhu, Michael R. Boyd, Xi Chen, Jacob Valiyaveettil, Veronica Ramirez-Alcantara, Antonio Ward
Publikováno v:
Cancer Research. 79:3864-3864
Over 90% of colorectal cancers harbor mutations in β-catenin or pathway components (e.g. APC) that stabilize β-catenin, causing nuclear translocation and constitutive Tcf-mediated transcription of genes encoding proteins essential for the prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aba0e13d34e17d31255a92a041bbe47
https://doi.org/10.1158/1538-7445.am2019-3864
https://doi.org/10.1158/1538-7445.am2019-3864
Autor:
Michael J. Roberts, Andrew D. Penman, Richard D. May, Kristy L. Berry, Murray Stackhouse, Yulia Maxuitenko, Robert J. Rooney, Tommie A. Gamble, Michael S. Koratich
Publikováno v:
Cancer Research. 74:3730-3730
The procedure to identify and develop an anti-cancer drug first involves testing drug candidates in cell lines followed by human tumor xenograft models, usually selected based upon the histotype of the cell lines in which the drug showed optimal acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e0b587017f7461a47b82183cfbc3be5
https://doi.org/10.1158/1538-7445.am2014-3730
https://doi.org/10.1158/1538-7445.am2014-3730
Autor:
Andrew D. Penman, Joseph F. Murphy, Michael J. Roberts, Murray Stackhouse, Richard D. May, Kristy L. Berry, Tommie A. Gamble, Michael S. Koratich, Robert J. Rooney, Yulia Maxuitenko
Publikováno v:
Cancer Research. 73:2778-2778
Traditionally, drug development has relied upon testing cancer drug candidates in cell lines. Active drugs are then tested in human tumor xenograft models, usually selected based upon the cell lines in which the drug showed activity. The majority of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d2b9dd0c9f1f2ee5e19e47e87e892e0
https://doi.org/10.1158/1538-7445.am2013-2778
https://doi.org/10.1158/1538-7445.am2013-2778
Autor:
Robert J. Rooney, Tommie A. Gamble, Andrew D. Penman, Kristy L. Berry, Richard D. May, Michael S. Koratich, Michael J. Roberts, William R. Waud, Murray Stackhouse, Yulia Maxuitenko, Meredith S. Plaxco
Publikováno v:
Cancer Research. 71:3943-3943
The total mRNA for each sample of 51 human tumor cell lines representative of 16 different tissues of origin was split into 3 replicates, and analyzed against the entire human genome using standard Affx WT procedures. Approximately 50% of the samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea79b75be5d55afa4e8cba2c1e70d78f
https://doi.org/10.1158/1538-7445.am2011-3943
https://doi.org/10.1158/1538-7445.am2011-3943
Autor:
Murray Stackhouse, Meredith S. Plaxco, Michael J. Roberts, Kristy L. Berry, Andrew D. Penman, Richard D. May, Yulia Maxuitenko, Robert J. Rooney, Tommie A. Gamble, William R. Waud, Michael S. Koratich
Publikováno v:
Cancer Research. 71:4418-4418
The NCI recently performed microarray expression analysis on its 60-panel of human tumor cell lines. This revealed important information, with some cell lines shown to be from a different tissue of origin than originally believed. Traditionally, pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb22d39e4b6af1285a62e230552009c5
https://doi.org/10.1158/1538-7445.am2011-4418
https://doi.org/10.1158/1538-7445.am2011-4418
Autor:
Ling Zhai, Zhican Qu, Ali Zamani, Rongbao Li, Murray A. Stackhouse, Yulia Maxuitenko, Kristy L. Berry, Michael J. Roberts
Publikováno v:
Cancer Research. 71:3114-3114
Tumor growth is not determined solely by the tumor cells but is governed by interactions between tumor cells and host stromal cells, including endothelial cell activation and fibroblastic stroma response. Tumor stroma profoundly influences many steps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7084382571565e49336812d9eacee9b0
https://doi.org/10.1158/1538-7445.am2011-3114
https://doi.org/10.1158/1538-7445.am2011-3114
Autor:
Wenyan Lu, Cuihong Lin, Yonghe Li, Ling Zhai, Traci Bethea, Kristy L. Berry, Zhican Qu, William R. Waud
Publikováno v:
FEBS Letters. (19):3120-3125
Mesd is a specialized chaperone for Wnt co-receptor low-density lipoprotein receptor-related protein-5 (LRP5) and LRP6, which contain four β-propeller/epidermal growth factor modules, named E1 to E4 from N- to C-terminal, in their extracellular doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4c31cdc2aa40c9655cc5382adf8d10